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| 1 | Nat Microbiol:已结首次构建出小鼠肠道微生物组数据库显示文摘小鼠模型通常被广泛用于药理学和医学研究。我们都知道小鼠肠道中的微生物群落通常会对研究结果产生明显的影响,然而目前研究者们并没有获取到关于小鼠肠道中栖息细菌群落的详细信息。近日刊登在国际杂志Nature Microbiology上的一篇研究报告中。德国慕尼黑理工大学的研究者通过研究首次收集到了小鼠肠道中的多种细菌群落。同时研究者还对其进行了分裂、特性分析。最后得到了100种细菌,其中还包括15种迄今为止未知的细菌群落。 | Lu, Qiulun Yao, Yufeng Hu, Zhenkun Hu, Changqing Song, Qixue Ye, Jian Xu, Chengqi Wang, Annabel Z. Chen, Qiuyun Wang, Qing Kenneth | 2016 | 现代生物医学进展2016，16，32： | 13 |
| 2 | 3D-printed models improve surgical planning for correction of severe postburn ankle contracture with an external fixator显示文摘Gradual distraction with an external fixator is a widely used treatment for severe postburn ankle contracture(SPAC).However,application of external fixators is complex,and conventional two-dimensional(2D)imaging-based surgical planning is not particularly helpful due to a lack of spatial geometry.The purpose of this study was to evaluate the surgical planning process for this procedure with patient-specific three-dimension-printed models(3DPMs).In this study,patients coming from two centers were divided into two cohorts(3DPM group vs.control group)depending on whether a 3DPM was used for preoperative surgical planning.Operation duration,improvement in metatarsal-tibial angle(MTA),range of motion(ROM),the American Orthopedic Foot and Ankle Society(AOFAS)scores,complications,and patient-reported satisfaction were compared between two groups.The 3DPM group had significantly shorter operation duration than the control group((2.0±0.3)h vs.(3.2±0.3)h,P<0.01).MTA,ROM,and AOFAS scores between the two groups showed no significant differences pre-operation,after the removal of the external fixator,or at follow-up.Plantigrade feet were achieved and gait was substantially improved in all patients at the final follow-up.Pin-tract infections occurred in two patients(one in each group)during distraction and were treated with wound care and oral antibiotics.Patients in the 3DPM group reported higher satisfaction than those in the control group,owing to better patient-surgeon communication.Surgical planning using patient-specific 3DPMs significantly reduced operation duration and increased patient satisfaction,while providing similar improvements in ankle movement and function compared to traditional surgical planning for the correction of SPAC with external fixators. | Youbai CHEN Zehao NIU Weiqian JIANG Ran TAO Yonghong LEI Lingli GUO Kexue ZHANG Wensen XIA Baoqiang SONG Luyu HUANG Qixu ZHANG Yan HAN | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，10： | 3 |
| 3 | Tracking Your Browser with High-Performance Browser Fingerprint Recognition Model显示文摘As the cyber security has attracted great attention in recent years,and with all kinds of tools’(such as Network Agent,VPN and so on)help,traditional methods of tracking users like log analysis and cookie have been not that effective.Especially for some privacy sensitive users who changed their browser configuration frequently to hide themselves.The Browser Fingerprinting technology proposed by Electronic Frontier Foundation(EFF)gives a new approach of tracking users,and then our team designed an enhanced fingerprint dealing solution based on browser fingerprinting technology.Our enhanced solution plays well in recognizing the similar fingerprints,but it is not that efficient.Nowadays we improve the algorithm and propose a high-performance,efficient Browser Fingerprint Recognition Model.Our new model reforms the fingerprint items set by EFF and propose a Fingerprint Tracking Algorithm(FTA)to deal with collected data.It can associate users with some browser configuration changes in different periods of time quickly and precisely.Through testing with the experimental website built on the public network,we prove the high-performance and efficiency of our algorithm with a 20%time-consuming decrease than ever. | Wei Jiang Xiaoxi Wang Xinfang Song Qixu Liu Xiaofeng Liu | 2020 | China Communications2020，17，3： | 2 |
| 4 | Water utilization of typical plant communities in desert steppe,China显示文摘Water is a limiting factor in the restoration and construction of desert steppe.Exploring plant water sources is necessary to understand soil-plant interactions and species coexistence;however,water sources of major plant communities within the desert steppe of Ningxia Hui Autonomous Region,China remain poorly understood.In this study,we analyzed the water uptake of plants in four typical communities:Agropyron mongolicum Keng.;Sophora alopecuroids Linn.;Stipa breviflora Griseb.,and Achnatherum splendens(Trin.)Nevski communities.Stable isotopesδD andδ^(18)O in the xylem of plant and soil water at different soil depths were analyzed.An IsoSource model was used to determine the soil depths from which plants obtained water.Results showed that A.mongolicum community obtained water predominantly from 0–20 and 40–80 cm depth,S.alopecuroids community from 0–20 cm depth,S.breviflora community from 0–40 cm depth,and A.splendens community from 0–20 and 80–140 cm depths.S.alopecuroides had a wider range of soil depths for water extraction,i.e.,utilizing different water sources depending on habitat,and the plasticity of its water uptake pattern determined its role in different communities.Water source of plants relayed heavily on the distribution of their roots.Competition for soil water exists between different plant life forms in the sierozem habitat(A.mongolicum,S.alopecuroids,and S.breviflora communities),and in the sandy soil habitat(A.splendens community).The use of soil water by A.splendens community is more spatially differentiated,and shrubs and herbs can coexist stably.Under the pattern of extended drought period in the future,sierozem habitat may be more favorable for the formation of a dominant monoculture community type of perennial fibrous plants.In aeolian sandy soil habitat,A.splendens had a strong competitive advantage,and the growth of shallow-rooted plants was easily suppressed. | CHEN Juan WANG Xing SONG Naiping WANG Qixue WU Xudong | 2022 | Journal of Arid Land2022，14，9： | 1 |
| 5 | Selective Carbon-Carbon Bond Amination with Redox-Active Aminating Reagents:A Direct Approach to Anilines显示文摘The structure of Montelukast-derivatives(12)in Table 2 and the structure of its product 25 in page s24 are wrong,and they should be Montelukast-derivatives(12)methyl(R,E)-2-(1-(1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate and methyl(R,E)-2-(1-(3-(2-aminophenyl)-1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)thio)-methyl)cyclopropyl)acetate(25). | Xu Qiu Yachong Wang Lingyu Su Rui Jin Song Song Qixue qin Junhua Li Baoning Zong Ning Jiao | 2023 | Chinese Journal of Chemistry2023，41，18： | 0 |
| 6 | Selective Carbon-Carbon Bond Amination with Redox-Active Aminating Reagents:A Direct Approach to Anilines显示文摘Amines are among the most fundamental motifs in chemical synthesis,and the introduction of amine building blocks via selective C-C bond cleavage allows the construction of nitrogen compounds from simple hydrocarbons through direct skeleton modification.Herein,we report a novel method for the preparation of anilines from alkylarenes via Schmidt-type rearrangement using redox-active amination reagents,which are easily prepared from hydroxylamine.Primary amines and secondary amines were prepared from corresponding alkylarenes or benzyl alcohols under mild conditions.Good compatibility and valuable applications of the transformation were also displayed. | Xu Qiu Yachong Wang Lingyu Su Rui Jin Song Song Qixue Qin Junhua Li Baoning Zong Ning Jiao | 2021 | Chinese Journal of Chemistry2021，39，11： | 0 |
| 7 | Nitromethane-Enabled Fluorination of Styrenes and Arenes显示文摘The electrophilic fluorination of unsaturated compounds provides a reliable approach to the generation of organofluorides,which are used widely in agrochemicals,pharmaceuticals,and other materials.Numerous active electrophilic fluorine reagents,such as the fluorine molecule(F_(2))or xenon difluoride(XeF_(2)),have been applied in fluorination.However,these reagents suffer from their hazardous,toxic,corrosive,and poor selective properties,and the relatively weak electrophilicity of Selectfluor or N-fluorobenzenesulfonimide(NFSI)usually limits their broad applications.Herein,we disclose nitromethane(MeNO_(2))as an efficient activator of Selectfluor and NFSI,as well as a stabilizer of carbocations.Therefore,the fluoro-azidation,fluoroamination,fluoroesterification of styrenes,and C–H fluorination of(hetero)arenes were well realized just by the facilitation of MeNO_(2).The mild reaction conditions and practicability made our current method a versatile protocol for accessing organofluorides. | Weijin Wang Tongyu Huo Xinyi Zhao Qixue Qin Yujie Liang Song Song Guosheng Liu Ning Jiao | 2020 | CCS Chemistry2020，2，6： | 0 |
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