|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Clinicopathologic factors influencing the accuracy of EUS for superficial esophageal carcinoma显示文摘AIM:To identify clinicopathologic factors influencing the accuracy of a high-frequency catheter probe endoscopic ultrasonography(EUS)for superficial esophageal carcinomas(SECs).METHODS:A total of 126 patients with endoscopically suspected SEC,who underwent EUS and curative treatment at Pusan National University Hospital during2005-2013,were enrolled.We reviewed the medical records of the 126 patients and compared EUS findings with histopathologic results according to clinicopathologic factors.RESULTS:A total of 114 lesions in 113 patients were included in the final analysis.The EUS assessment of tumor invasion depth was accurate in 78.9%(90/114)patients.Accuracy did not differ according to histologic type,tumor differentiation,tumor location,or macroscopic shape.However,accuracy significantly decreased for tumors≥3 cm in size(P=0.002).Overestimation and underestimation of the invasion depth occurred for 11(9.6%)and 13 lesions(11.4%),respectively.In multivariate analyses,tumor size≥3 cm was the only factor significantly associated with EUS accuracy(P=0.031),and was specifically associated with the underestimation of invasion depth.CONCLUSION:EUS using a high-frequency catheter probe generally provides highly accurate assessments of SEC invasion depth,but its accuracy decreases for tumors≥3 cm. | Jung Im Jung Gwang Ha Kim Hoseok I Do Youn Park Tae Kyun Kim Young Hwa Cho Yong Wan Sung Mun Ki Choi Bong Eun Lee Geun Am Song | 2014 | World Journal of Gastroenterology2014，20，20： | 9 |
| 2 | Bilateral primary breast lymphoma显示文摘 | Jung Im Yi Byung Joo Chae Ja Seong Bae Bong Joo Kang Ahwon Lee Byung Joo Song Sang Seol Jung | 2010 | Chinese Medical Journal2010，，11： | 5 |
| 3 | Human mesenchymal stem cells derived from umbilical cord and bone marrow exert immunomodulatory effects in different mechanisms显示文摘BACKGROUND Mesenchymal stem cells(MSCs)are an attractive tool to treat graft-versus-host disease because of their unique immunoregulatory properties.Although human bone marrow-derived MSCs(BM-MSCs)were the most widely used MSCs in cell therapy until recently,MSCs derived from human umbilical cords(UC-MSCs)have gained popularity as cell therapy material for their ethical and noninvasive collection.AIM To investigate the difference in mechanisms of the immunosuppressive effects of UC-MSCs and BM-MSCs.METHODS To analyze soluble factors expressed by MSCs,such as indolamine 2,3-dioxygenase,cyclooxygenase-2,prostaglandin E2 and interleukin(IL)-6,inflammatory environments in vitro were reconstituted with combinations of interferon-gamma(IFN-γ),tumor necrosis factor alpha and IL-1βor with IFN-γalone.Activated T cells were cocultured with MSCs treated with indomethacin and/or anti-IL-10.To assess the ability of MSCs to inhibit T helper 17 cells and induce regulatory T cells,induced T helper 17 cells were cocultured with MSCs treated with indomethacin or anti-IL-10.Xenogeneic graft-versus-host disease was induced in NOG mice(NOD/Shi-scid/IL-2Rγnull)and UC-MSCs or BM-MSCs were treated as cell therapies.RESULTS Our data demonstrated that BM-MSCs and UC-MSCs shared similar phenotypic characteristics and immunomodulation abilities.BM-MSCs expressed more indolamine 2,3-dioxygenase after cytokine stimulation with different combinations of IFN-γ,tumor necrosis factor alpha-αand IL-1βor IFN-γalone.UC-MSCs expressed more prostaglandin E2,IL-6,programmed death-ligand 1 and 2 in the in vitro inflammatory environment.Cyclooxygenase-2 and IL-10 were key factors in the immunomodulatory mechanisms of both MSCs.In addition,UC-MSCs inhibited more T helper 17 cells and induced more regulatory T cells than BM-MSCs.UC-MSCs and BM-MSCs exhibited similar effects on attenuating graft-versus-host disease.CONCLUSION UC-MSCs and BM-MSCs exert similar immunosuppressive effects with different mechanisms involved.These findings suggest that UC-MSCs have distinct immunoregulatory functions and may substitute BM-MBSCs in the field of cell therapy. | Yunejin Song Jung-Yeon Lim Taekyu Lim Keon-Il Im Nayoun Kim Young-Sun Nam Young-Woo Jeon Jong Chul Shin Hyun Sun Ko In Yang Park Seok-Goo Cho | 2020 | World Journal of Stem Cells2020，12，9： | 4 |
| 4 | Self-assembled nanocomplex between polymerized phenylboronic acid and doxorubicin for efficient tumor-targeted chemotherapy显示文摘 | Junseok LEE Jinhwan KIM Yeong Mi LEE Dongsik PARK Sooseok IM Eun Ho SONG Hansoo PARK Won Jong KIM | 2017 | Acta Pharmacologica Sinica2017，38，6： | 3 |
| 5 | Comparison of endoscopic ultrasonography and conventional endoscopy for prediction of depth of tumor invasion in early gastric cancer显示文摘 | J. Choi S. Kim J. Im J. Kim H. Jung I. Song | 2010 | Endoscopy2010，，09： | 3 |
| 6 | Identification of optimal molecular size of modified Aloe polysaecharides with maximum immunomodulatory activity 显示文摘 | IM S A OH S T SONG S | 2005 | Int Immunopharmaeol2005，5，2： | 1 |
| 7 | Potentially unstable intertrochanteric fractures 显示文摘 | Im G I Shin Y W Song Y J | 2005 | J Orthop Trauma2005，19，1： | 1 |
| 8 | Mediastinal tuberculous lymphadenitis : CT manifestations 显示文摘 | Im JG Song KS Kang HS | 1987 | Radiology1987，164，1： | 1 |
| 9 | Potentially unstable intertrochanteric fractures显示文摘 | Im G I Shin Y W Song Y J | 2005 | J Orthop Trauma2005，19，1： | 1 |
| 10 | Does strategic planning enhance or impede innovation and firm performance显示文摘 | SONG M IM S BIJ H | 2011 | Journal of Product Innovation Management2011，28，4： | 1 |
| 11 | Phenotypic and population differences in the association between CILP and lumbar disc disease显示文摘 | Virtanen IM Song YQ Cheung KM | 2007 | J Med Genet2007，44，4： | 1 |
| 12 | Mediastinal tuberculous lym- phadenitis:CT manifestations显示文摘 | Im JG Song KS Kang HS | 1987 | Radiology1987，164，1： | 1 |
| 13 | Localized amyloidosis of therespiratory system:CT features显示文摘 | Kim HY Im JG Song KS | 1999 | J Comput Assist Tomogr1999，23，： | 1 |
| 14 | Mediastinal tuberculous lymphadenitis:CT manifestations显示文摘 | Im J G Song K S Kang H S | 1987 | Radiology1987，164，1： | 1 |
| 15 | Fractures to the posterior wall of the acetabulum managed with screws alone显示文摘 | Im G I Shin Y W Song Y J | 2005 | J Trauma2005，58，2： | 1 |
| 16 | Cooperation-based dynamic spectrum leasing via multi-winner auction of multiple bands显示文摘 | Lira H Song M Im G | 2013 | IEEE Transactions on Communications2013，61，4： | 1 |
| 17 | Magnolol reduces UVB-induced photodamage by regulating matrix metalloproteinase activity 显示文摘 | Im AR Song JH Lee MY | 2015 | Environ Toxicol Pharmacol2015，39，1： | 1 |
| 18 | Fractures to the posterior wall of the ac- etabulum managed with screws alone显示文摘 | Im GZ Shin YW Song YJ | 2005 | J Trauma2005，58，2： | 1 |
| 19 | Formaldehyde adsorption and physical characteristics of hydrothermal reacted panel with porous materials 显示文摘 | Im D H Chu Y S Song H | 2009 | Journal of the Korean Ceramic Society2009，46，6： | 1 |
| 20 | Potentially unstable intertrochanteric fractures 显示文摘 | Im GI Shin YW Song YJ | 2005 | J Orthop Trauma2005，1，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员