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您的检索式：作者名="Song Rae Kim"
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| 1 | Engineering of hollow polymeric nanosphere-supported imidazolium-based ionic liquids with enhanced antimicrobial activities显示文摘The design of stable,efficient and processable bactericidal materials represents a significant challenge for combating multidrugresistant bacteria in a variety of engineering fields.Herein,we report a facile strategy for the preparation of hollow polymeric nanosphere(HPN)-supported imidazolium-based ionic liquids(denoted as HPN-ILs)with superior antimicrobial activities.HPNILs were tailored by moderate Friedel−Crafts polymerization followed by the sequential covalent bonding of imidazole and bromoalkene.The resultant HPN-ILs have uniform hollow spherical morphology,an adequate surface area,and excellent physicochemical stability.Furthermore,they are highly active against both Gram-positive and Gram-negative bacteria and exhibit typical time/dosage-dependent antibacterial activities.The rational combination of porous HPNs and antibacterial ILs to generate an all-in-one entity may open new avenues for the design and fabrication of efficient bacteriostatic agents.Moreover,HPN-ILs have good biocompatibility and can also be loaded onto diverse matrices,and thus could extend their practical bactericidal application in the potential biomedical-active field. | Yu Zhang Shuwei Li Yixin Xu Xinyun Shi Mingxin Zhang Yingning Huang Ying Liang Yaqiong Chen Wanli Ji Jung Rae Kim Wenliang Song Deng-Guang Yu Il Kim | 2022 | Nano Research2022，15，6： | 1 |
| 2 | Palliative Treatment of Unresectable Esophagogastric Junction Tumors: Balloon Dilation Combined with Chemotherapy and/or Radiation Therapy and Metallic Stent Placement显示文摘 | Jin Hyoung Kim Ho-Young Song Ji Hoon Shin Tae Won Kim Kyung Rae Kim Sung-Bae Kim Seung-Il Park Jong Hoon Kim Eugene Choi | 2008 | Journal of Vascular and Interventional Radiology2008，，6： | 1 |
| 3 | Protective Effect of Brassica napus L.Hydrosols against Inflammation Response in RAW 264.7 Cells显示文摘Objective:To demonstrate the anti-inflammatory activity of Brassica napus L.hydrosols(BNH)in lipopolysaccharide(LPS)-stimulated RAW 264.7 cells.Methods:Composition analysis of BNH was conducted via gas chromatography-mass spectrometry after BNH were extracted.The nitric oxide(NO)production was measured using the Griess assay.Prostaglandin E2(PGE2)production was evaluated with enzyme-linked immunosorbent assay.The effects of BNH on LPS-induced pro-inflammatory enzymes including inducible nitric oxide synthase(iNOS)and cyclooxygenase-2(COX-2)were evaluated using Western blot analysis.Furthermore,phosphorylation of nuclear factor-kappa B(N F-k B)and nuclear translocation of N F-k B p65 were evaluated with Western blot analysis and immunofluorescence staining,respectively.Results:Compared with LPS-stimulated cells,BNH markedly decreased the generation of NO and PGE_(2)in LPS-stimulated RAW 264.7 cells(P<0.01 or P<0.05).Moreover,BNH inhibited protein levels of iNOS and COX-2(P<0.01).Phosphorylation of NF-k B and nuclear translocation of NF-k B p65 was significantly inhibited by BNH(P<0.01 or P<0.05).Conclusion:The anti-inflammatory activities of BNH were mediated via blockage of the N F-k B signaling pathways in LPS-stimulated RAW 264.7 cells. | Su-Hyeon Cho Song Rae Kim Myeong Seon Jeong Miri Choi SeonJu Park Kil-Nam Kim | 2021 | Chinese Journal of Integrative Medicine2021，27，4： | 0 |
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