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| 1 | Magnetic resonance imaging features of extremity sarcomas of uncertain differentiation显示文摘 | NAIR L | 2007 | Clin Radiol2007,62,10: | 1 |
| 2 | Effect of cosolvent organic molecules on the adsorption and structural properties of soft - templated ordered mesoporous alumina 显示文摘 | Stacy M G Mietek J | 2012 | Journal of Colloid and Interface Science2012,367,: | 1 |
| 3 | Electrosteric stabilization of concentrated cement suspensions imparted by a strong anionic polyelectrolyte and a non-ionic polymer显示文摘 | Stacy G Bike Victor C Li | 2006 | Cement and Concrete Research2006,36,: | 1 |
| 4 | Serological profiling of Crohn’s disease and ulcerative colitis patients reveals anti-microbial antibody signatures显示文摘BACKGROUND The healthcare burden of inflammatory bowel disease(IBD)is rising globally and there are limited non-invasive biomarkers for accurate and early diagnosis.AIM To understand the important role that intestinal microbiota play in IBD pathogenesis and identify anti-microbial antibody signatures that benefit clinical management of IBD patients.METHODS We performed serological profiling of 100 Crohn’s disease(CD)patients,100 ulcerative colitis(UC)patients and 100 healthy controls against 1173 bacterial and 397 viral proteins from 50 bacteria and 33 viruses on protein microarrays.The study subjects were randomly divided into discovery(n=150)and validation(n=150)sets.Statistical analysis was performed using R packages.RESULTS Anti-bacterial antibody responses showed greater differential prevalence among the three subject groups than anti-viral antibody responses.We identified novel antibodies against the antigens of Bacteroidetes vulgatus(BVU_0562)and Streptococcus pneumoniae(SP_1992)showing higher prevalence in CD patients relative to healthy controls.We also identified antibodies against the antigen of Streptococcus pyogenes(SPy_2009)showing higher prevalence in healthy controls relative to UC patients.Using these novel antibodies,we built biomarker panels with area under the curve(AUC)of 0.81,0.87,and 0.82 distinguishing CD vs control,UC vs control,and CD vs UC,respectively.Subgroup analysis revealed that penetrating CD behavior,colonic CD location,CD patients with a history of surgery,and extensive UC exhibited highest antibody prevalence among all patients.We demonstrated that autoantibodies and anti-microbial antibodies in CD patients had minimal correlation.CONCLUSION We have identified antibody signatures for CD and UC using a comprehensive analysis of antimicrobial antibody response in IBD.These antibodies and the source microorganisms of their target antigens improve our understanding of the role of specific microorganisms in IBD pathogenesis and,after future validation,should aid early and accurate diagnosis of IBD. | Mahasish Shome Lusheng Song Stacy Williams Yunro Chung Vel Murugan Jin G Park William Faubion Shabana F Pasha Jonathan A Leighton Joshua LaBaer Ji Qiu | 2022 | World Journal of Gastroenterology2022,28,30: | 1 |
| 5 | Arecibo radar mapping of the lunar poles: A search for ice deposits显示文摘 | STACY N J S CAMPBELL D B FORD P G | 1997 | Science1997,276,: | 1 |
| 6 | Making energy conservation pay through automation 显示文摘 | FUNK G L HONSTON B F STACY G D | 1978 | Chemical Engineering Process1978,74,5: | 1 |
| 7 | Prices,incentives and choice of management form显示文摘 | Sirmans C F Turnbull Geoffrey K | 1999 | Regional Science and Urban Economics1999,29,2: | 1 |
| 8 | Allelopathic effects ofvolatile cineole on two weedy plant species显示文摘 | JOANNE G R STACY N A FRANCK E D | 2000 | Journal of ChemicalEcology2000,26,1: | 1 |
| 9 | Bariatric surgery for type 2 diabetes:Weighing the impact for obese patients显示文摘 | SANGEETA R K PATRICK G STACY B | 2010 | Cleve Clin J Med2010,77,7: | 1 |
| 10 | Prices, incentives and choice of management显示文摘 | G Stacy Sirmans C F Sirmans Geoffrey K Turnbull | 1999 | Regional Science & Urban Economics1999,29,2: | 1 |
| 11 | A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients 显示文摘 | Daniel J S Richard M G Stacy D J | 2001 | N Engl Med2001,345,15: | 1 |
| 12 | Novel tricyclic poly (ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity:design,synthesis,and X-ray cocrystal structure显示文摘 | Stacie S Koch C Lars H Thoresen J G | 2002 | J Med Chem2002,45,23: | 1 |
| 13 | Making energy conservation pay through automation显示文摘 | Funk G L Honston B F Stacy G D | 1978 | Chemical Engineering Progress1978,74,5: | 1 |
| 14 | Is HbA(1c) affected by glycemic instability?显示文摘 | DERR R GARRETT E STACY G A | 2003 | Diabetes Care2003,26,10: | 1 |
| 15 | Optimization Saves Ener- gy at Polysar Steam and Power Plant显示文摘 | Laspisa R L Stacy G Sochan H M | 1978 | Oil and Gas Journal1978,76,25: | 1 |
| 16 | Investigating Sponsorship Effeetiveness: Do Less Familiar Brands Have an Advantage over more Familiar Brands in Single and Multiple Sponsorship Arrangement显示文摘 | STACY L G JUDITH A G F | 2005 | Journal of Brand Management2005,13,1: | 1 |
| 17 | Cause-related Marketing (CRM) 显示文摘 | STACY L G JUDITH A G F | 2007 | Journal of Advertising2007,36,4: | 1 |
| 18 | Ultractructural study of sercetory granules in the corpus luteum of sheep during the estrous cycle显示文摘 | Gemmell R T Stacy B D Thorburn G D | 1974 | Biol Reprod1974,11,4: | 1 |
| 19 | Radar mapping of the lunar poles:A search for ice deposits显示文摘 | Stacy N J Campbell D B Ford P G | 1997 | Science1997,276,: | 1 |
| 20 | The synthesis of DL-, -diethylcysteine and DL--ethyl-/3-methylcys- teine显示文摘 | Vigneaud V Stacy G W Todd D | 1948 | J Biol Chem1948,176,: | 1 |