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| 1 | Intracolonic injection ofglycerol: a model for abdominal pain in irritable bowel syndrome 显示文摘 | Louvel D Delvaux M Staumont G | 1996 | Gastroenterology1996，110，2： | 1 |
| 2 | Intracolonic injection of glycerol: a model for abdominal pain in irritable bowel syndrome显示文摘 | Louvel D Delvaux M Staumont G | 1996 | Gastroenterology1996，10，2： | 1 |
| 3 | Successful autologous bone marrow transplantation in intravascular lymphonatosis显示文摘 | Rose C Staumont D Jouet JP | 1999 | Br J Haematol1999，105，1： | 1 |
| 4 | Activation of the D prostanoid receptor 1 regulates immune and skin allergic responses显示文摘 | Angeli V Staumont D Charbonnier AS | 2004 | J Immunol2004，172，6： | 1 |
| 5 | Intracolonic injection of glycerol: a model for abdominal pain in irritable bowel syndrom 显示文摘 | Louvel D Delvaux M Staumont G | 1996 | Gastroenterology1996，110，2： | 1 |
| 6 | Sennosides and human colonic motility显示文摘 | Staumont O Frexinos J Fioramonti J | 1988 | Pharmacology1988，36，1： | 1 |
| 7 | Intracolonic injection of glycerol: a moder for abdominal pain in irritable bowel syndrcme显示文摘 | Lonvel D Delvanx M Staumont G | 1996 | Gextroenterology1996，110，2： | 1 |
| 8 | 显示文摘 | Louvel D Delvaux M Staumont G | 1996 | Gastroenterology1996，110，： | 1 |
| 9 | Intracolonic injection of glycerol: a model for abdominal pain in irritable bowel syndrome?显示文摘 | Louvel D Delvaux M Staumont G | 1996 | Gastroenterology1996，110，2： | 1 |
| 10 | Intracolonic iniection of glycerol: a model for abdomi nal pain in irritable bowel syndrome 显示文摘 | Louvel D Delvaux M Staumont G Camman F Fioramonti J Bueno L | 1996 | Gastroenterology1996，110，： | 1 |
| 11 | Effects of sennosides on colonic myoelectrical activity in man显示文摘 | Jacques Frexinos MD Ghislain Staumont MD Jean Fioramonti DS Lionel Bueno DS | 1989 | Digestive Diseases and Sciences1989，，2： | 1 |
| 12 | Inhibition of the colornc motor re-sponse to eating by pinaverium bromide in irritable bowel syndrom pa-tients显示文摘 | Fioramonti J Frexinos J Staumont G | 1988 | Fundam Clin Pharmocol1988，21，1： | 1 |
| 13 | Effects of sennosides on colonic myoelectrical activity in man显示文摘 | Jacques Frexinos Ghislain Staumont Jean Fioramonti Lionel Bueno | 1989 | Digestive Diseases and Sciences1989，，： | 1 |
| 14 | Differdncesbetween jejunal myoelectric activity after a meal and duting phase 2of migrateng motor complex in healthy humans显示文摘 | Staumont G Delvaux M Fioramonti J de al | 1992 | Dig Dis Sci1992，37，： | 1 |
| 15 | Successful autologous bone marrow transplantation in intravascular lymphonatosis显示文摘 | Staumont D Jouet JP | 1999 | Br J Haematol1999，105，1： | 1 |
| 16 | Intracolonic injection of glycerol; a model for abdominal pain in irritable bowel syndrome? 显示文摘 | Louvel D Delvaux M Staumont G | 1996 | Gastroenlerology1996，110，2： | 1 |
| 17 | Intracolonic injection of glycerol:a model for abdominal pain in irritable bowel syndrome显示文摘 | Louvel D Delvaux M Staumont G | | Gastroenterology0，110，35： | 1 |
| 18 | Elaboration and validation of Crohn's disease anoperineal lesions consensual definitions显示文摘AIM To establish consensual definitions of anoperineal lesions of Crohn's(APLOC) disease and assess interobserver agreement on their diagnosis between experts.METHODS A database of digitally recorded pictures of APLOC was examined by a coordinating group who selected two series of 20 pictures illustrating the various aspects of APLOC. A reading group comprised: eight experts from the Société Nationale Fran?aise de Colo Proctologie group of study and research in proctology and one academic dermatologist. All members of the coordinating and reading groups participated in dedicated meetings. The coordinating group initially conducted a literature review to analyse verbatim descriptions used to evaluate APLOC. The study included two phases: establishment of consensual definitions using a formal consensus method and later assessment of interobserver agreement on the diagnosis of APLOC using photos of APLOC, a standardised questionnaire and Fleiss' s kappa test or descriptive statistics.RESULTS Terms used in literature to evaluate visible APLOC did not include precise definitions or reference to definitions. Most of the expert reports on the first set of photos agreed with the main diagnosis but their verbatim reporting contained substantial variation. The definitions of ulceration(entity, depth, extension), anal skin tags(entity, inflammatory activity, ulcerated aspect), fistula(complexity, quality of drainage, inflammatory activity of external openings), perianal skin lesions(abscess, papules, edema, erythema) and anoperineal scars were validated. For fistulae, they decided to follow the American Gastroenterology Association's guidelines definitions. The diagnosis of ulceration(κ = 0.70), fistulae(κ = 0.75), inflammatory activity of external fistula openings(86.6% agreement), a b s c e s s e s( 8 4. 6 % a g r e e m e n t) a n d e r y t h e m a(100% agreement) achieved a substantial degree of interobserver reproducibility. CONCLUSION This study constructed consensual definitions of APLOC and their characteristics and showed that experts have a fair level of interobserver agreement when using most of the definitions. | Clémence Horaist Vincent de Parades Laurent Abramowitz Paul Benfredj Guillaume Bonnaud Dominique Bouchard Nadia Fathallah Agnès Sénéjoux Laurent Siproudhis Ghislain Staumont Manuelle Viguier Philippe Marteau | 2017 | World Journal of Gastroenterology2017，23，29： | 0 |
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