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| 1 | Antioxidant enriched enteral nutrition and oxidative stress after major gastrointestinal tract surgery显示文摘AIM: To investigate the effects of an enteral supple-ment containing antioxidants on circulating levels of antioxidants and indicators of oxidative stress after major gastrointestinal surgery.METHODS: Twenty-one patients undergoing major upper gastrointestinal tract surgery were randomised in a single centre, open label study on the effect of postoperative enteral nutrition supplementedwith antioxidants. The effect on circulating levels of antioxidants and indicators of oxidative stress, such as F2-isoprostane, was studied. RESULTS: The antioxidant enteral supplement showed no adverse effects and was well tolerated. After surgery a decrease in the circulating levels of antioxidant parameters was observed. Only selenium and glutamine levels were restored to pre-operative values one week after surgery. F2-isoprostane increased in the first three postoperative days only in the antioxidant supplemented group. Lipopolysaccharide binding protein (LBP) levels decreased faster in the antioxidant group after surgery.CONCLUSION: Despite lower antioxidant levels there was no increase in the circulating markers of oxidative stress on the first day after major abdominal surgery. The rise in F2-isoprostane in patients receiving the antioxidant supplement may be related to the conversion of antioxidants to oxidants which raises questions on antioxidant supplementation. Module AOX restored the postoperative decrease in selenium levels. The rapid decrease in LBP levels in the antioxidant group suggests a possible protective effect on gut wall integrity. Further studies are needed on the role of oxidative stress on outcome and the use of antioxidants in patients undergoing major abdominal surgery. | Mireille FM van Stijn Gerdien C Ligthart-Melis Petra G Boelens Peter G Scheffer Tom Teerlink Jos WR Twisk Alexander PJ Houdijk Paul AM van Leeuwen | 2008 | World Journal of Gastroenterology2008，14，45： | 4 |
| 2 | Systematic review of cystic duct closure techniques in relation to prevention of bile duct leakage after laparoscopic cholecystectomy显示文摘AIM To study the effect of different techniques of cystic duct closure on bile leakage after laparoscopic cholecystectomy(LC) for biliary disease.METHODS A systematic search of MEDLINE, Cochrane and EMBASE was performed. Rate of cystic duct leakage(CDL) was the primary outcome. Risk of bias was evaluated. Odds ratios were analyzed for comparison of techniques and pooled event rates for non-comparative analyses. Pooled event rates were compared for each of included techniques.RESULTS Out of 1491 articles, 38 studies were included. A total of 47491 patients were included, of which 38683(81.5%)underwent cystic duct closure with non-locking(metal)clips. All studies were of low-moderate methodological quality. Only two studies reported separate data on uncomplicated and complicated gallbladder disease. For overall CDL, an odds ratio of 0.4(95%CI: 0.06-2.48)was found for harmonic energy vs clip closure and an odds ratio of 0.17(95%CI: 0.03-0.93) for locking vs non-locking clips. Pooled CDL rate was around 1% for harmonic energy and metal clips, and 0% for locking clips and ligatures. CONCLUSION Based on available evidence it is not possible to either recommend or discourage any of the techniques for cystic duct closure during LC with respects to CDL,although data point out a slight preference for locking clips and ligatures vs other techniques. No separate recommendation can be made for complicated gallbladder disease. | Aafke H van Dijk Stijn van Roessel Philip R de Reuver Djamila Boerma Marja A Boermeester Sandra C Donkervoort | 2018 | World Journal of Gastrointestinal Surgery2018，10，6： | 3 |
| 3 | Natural resource abundance and economic growth revisited显示文摘 | JEAN-PHILIPPE C STIJNS | 2005 | Resources Policy2005，，30： | 1 |
| 4 | Estimating the impact of water pricing on water use efficiency in semi-ar- id cropping system:an application of probabilistically con- strained nonparametric efficiency analysis 显示文摘 | PRAKASHAN C V STIJN S GUIDO V H | 2013 | Water Re- sources Management2013，27，1： | 1 |
| 5 | Prediction of Dose Escalation for Rheumatoid Arthritis Patients under Infliximab Treatment显示文摘 | Stijn V L Bert V C Jeroen M Bart W | 2006 | Engineering Applications of Artificial Intelligence2006，19，7： | 1 |
| 6 | Photography, public pedagogy and the politics of place-making in post-industrial areas显示文摘 | Maarten L Gillian C Stijn O | 2012 | Social and Cultural Geography2012，13，7： | 1 |
| 7 | Enterprise performance and management turnover in the czech republic显示文摘 | STIJN C SIMEON D | 1999 | European Economic Review1999，43，46： | 1 |
| 8 | Usefulness of Contrast-Enhanced Ultrasound for Detection of Carotid Plaque Ulceration in Patients With Symptomatic Carotid Atherosclerosis显示文摘 | Ten Kate Gerrit L van Dijk Anouk C van den Oord Stijn CH | 2013 | Am J Cardiol2013，112，2： | 1 |
| 9 | Natural Resource Abundance and Economic Growth Re- visited显示文摘 | Stijns J C | 2005 | Resources Policy2005，，30： | 1 |
| 10 | Natural Resource Abundance and Economic Growth Revisited显示文摘 | Stijns Jean-Philippe C | 2005 | Resources Policy2005，30，： | 1 |
| 11 | Transmission of bulk power显示文摘 | Stijn C Ronnie B | 2009 | IEEE Industrial Electronics Magazine2009，3，3： | 1 |
| 12 | Natural resource abundance and economic growth revisited显示文摘 | Stijns J C | 2005 | Resources Policy2005，30，2： | 1 |
| 13 | Natural Resource Abundance and Human Capital Accumulation 显示文摘 | STIJNS J-P C | 2006 | World Development2006，34，6： | 1 |
| 14 | Nature Resource Abundance and Economic Growth Revisited 显示文摘 | Jean--Philippe C Stijns | 2005 | Resource Policy2005，30，2： | 1 |
| 15 | Natural resource abundance and economit: growth revisited显示文摘 | Stijns J C | 2005 | Resources Policy2005，30，： | 1 |
| 16 | Risk management in developing countries 显示文摘 | STIJN C | 1993 | World Bank - Technical Papers1993，，： | 1 |
| 17 | Natural Resource Abundance and Economic Growth显示文摘 | Stijns Jean-Philippe C | 2005 | Resources Policy2005，，30： | 1 |
| 18 | Natural Resource Abundance and Economic Growth revisited显示文摘 | Stijns J-P C | 2005 | Resources Policy2005，30，2： | 1 |
| 19 | Electronic Fin- ance: A New Approach to Financial Sector Development? 显示文摘 | Stijn Claessens Thomas C Glaessner Daniela Klingebiel | 2002 | 2002，，： | 1 |
| 20 | Natural resource abundance and economic growth revisited 显示文摘 | Stijns J P C | 2005 | Resources Policy2005，30，2： | 1 |
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