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| 1 | Improved hemostasis with major hepatic resection in the current surgical era显示文摘Background: Major hepatic resection, predominantly performed for oncologic intent, is a complex procedure with the potential for severe intraoperative hemorrhage. The current surgical era has the ability to improve hemostasis throughout the performance of major hepatic resections which decreases blood transfusions and the detrimental effects associated with transfusion. We evaluated hemostasis and outcomes in the current surgical era of performing hepatic resections. Methods: Utilizing the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) database all major hepatic resections performed between 2012 and 2016 were analyzed in regards to hemostasis. Hemostasis was evaluated by the need for and magnitude of blood transfusions. Additional perioperative variables (including operative time, length of hospital stay, and mortality rates) were analyzed to assess for outcomes with hemostasis. The NSQIP results were compared to previous publications involving major hepatic resections to detect improvement in hemostasis and outcomes in the current surgical era. Results: A total of 22777 major hepatic resections met the inclusion criteria for analysis in the NSQIP database. An additional 21198 cases were compiled within the selected publications for comparative analysis. The transfusion rate in the current surgical era was 13.3% versus 38.7% in the previous era ( P = 0.0001). When a transfusion was required in the current surgical era there was a two-fold reduction in the number of units transfused (1.5 U vs. 3.8 U, P = 0.0001). Statistically significant improvements in operative time and length of hospital stay were presented within the current surgical era ( P = 0.0001). When a transfusion was required there was an increased relative risk score of 7 for mortality (4.9% vs. 0.7%, P = 0.0001), however, improvement in mortality rates did not reach statistical significance across surgical eras (1.3% vs. 4.0%, P = 0.0001). Conclusions: The conduction of major hepatic resection in the current surgical era is more hemostatic. Correlated with improved hemostasis are better outcomes for both clinical and financial endpoints. These findings should encourage continued and increased performance of major hepatic resections. | Christopher W Mangieri Matthew A Strode Bradley C Bandera | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，5： | 3 |
| 2 | Supercritical fluid chromatography of Ginkgolide A,B,C and J and bilobalide显示文摘 | Strode T B Taylor L T Van Beek T A | 1996 | J Chromatogr A1996，738，： | 2 |
| 3 | Supercritieal fluid chromatography of ginkgolides A, B, C, and J and bilobalide显示文摘 | J Thomposon B Strode III Larry T Taylor Teris A Van Beek | 1996 | J Chromatogr A1996，738，： | 1 |
| 4 | The Anopheles gambiae detoxification chip: a highly specific microarray to study metabolic- based insecticide resistance in malaria vectors显示文摘 | DAVID J P STRODE C VONTAS J | 2005 | Proc Natl Acad Sci USA2005，，： | 1 |
| 5 | Genomic analysis of detoxification genes in the mosquito Aedes aegypti 显示文摘 | STRODE C WONDJI C S DAVID J P | 2008 | In- sect Biochem Mol Biol2008，38，1： | 1 |
| 6 | Fundamental studies of thermal- structural effects on orbiting trusses 显示文摘 | MAHANEY J STRODE K B | 1982 | AIAA Paper1982，82，2： | 1 |
| 7 | The Anopheles gambiae detoxification chip:A highly specific microarray to study metabolic-based insecticide in malaria vectors 显示文摘 | DAVID J P STRODE C VONTAS J | 2005 | Proc Natl Acad Sci USA2005，102，11： | 1 |
| 8 | Supercritieal fluid chromatography of ginkgolides A,B,C and J and bilobalide 显示文摘 | Strode Ⅲ Hompson B Taylor LT | 1996 | Journal of Chromatography A1996，738，： | 1 |
| 9 | Adapting multiple-family Group treatment for barin and spinal cord injury intervention development and preliminary outcomes显示文摘 | Rodgers ML Strode AD Noretl DM | 2007 | America Joural of Physical Medicine and Rehabilitation2007，86，6： | 1 |
| 10 | The Anopheles gambiae detoxification chip : a highly specific microarray to study metabolic-based insecticide in malaria vectors 显示文摘 | David JP Strode C Vontas J | 2005 | Proc Natl Acad Sci USA2005，102，11： | 1 |
| 11 | Adapting multiple- family group treatment for brain and spinal cord injury interven- tion development and preliminary outcomes显示文摘 | Rodgers ML Strode AD Norell DM | 2007 | American Journal of Physical Medicine and Rehabilitation2007，86，6： | 1 |
| 12 | Technical and clinical progress in telemedicine显示文摘 | Strode SW Gustke S Allen A | 1999 | JAMA1999，281，12： | 1 |
| 13 | Feasibility of lovastatin analysis by packed column supercritical fluid chromatography with ultraviolet detection显示文摘 | Strode J T B Taylor L T HOWARD A L | 1999 | J Pharm Biomed Anal1999，20，： | 1 |
| 14 | The Anopheles gambiae de- toxification chip: a highly specific microarray to study metabolic- based insecticide resistance in malaria vectors 显示文摘 | David JP Strode C Vontas J | 2005 | Proc Natl Acad Sci U S A2005，102，11： | 1 |
| 15 | Genomie analysis of de toxification genes in the mosquito Aedes aegypti 显示文摘 | Strode C Wondji C S David J P | 2008 | Insect Biochemistry and Molecular Biology2008，38，1： | 1 |
| 16 | Differential expression of the detoxificatin genes in the different life stages of the ma laria vector Anopheles gambiae显示文摘 | Strode C Steen K Ortelli F | 2006 | Insect Molecular Biology2006，15，： | 1 |
| 17 | Preimplantation diagnosis to create ' saviour siblings': a critical discussion of the current and future legal frameworks in South Africa 显示文摘 | Strode A Soni S | 2011 | S Afr Med J2011，102，1： | 1 |
| 18 | Supercriticalfluid chromatography of ginkgolides A,B,C and J and bilobalide显示文摘 | StrodeⅢ Larry T Taylor | 1996 | Journal of Chromatography A1996，738，2： | 1 |
| 19 | Institutional Im- provement in Weight Loss after Laparoscopic Sleeve Gastreetomy 显示文摘 | Mangieri CW Strode MA Sherman WE | 2016 | Am Surg2016，82，5： | 1 |
| 20 | Cross-induction of detnx- itcation genes by environmental xenobiotics and insecticides in the mosquito Aedes aegypti: impact on larval tolerance to chemical in- secticides 显示文摘 | Poupardin R Reynaud S Strode C | 2008 | Insect Biochem Mol Biol2008，38，5： | 1 |
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