|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Antidepressant-like effect of active fraction of Polyrhachisvicina Roger in a rat depression model显示文摘OBJECTIVE: To investigate the antidepressant-likeeffect of active fraction of Polyrhachis vicina Roger(AFPR) in a rat depression model, and to elucidate the underlying mechanism.METHODS: AFPR was extracted with ethanol followed by petroleum ether. Its antidepressant-like effect was investigated in mice by tail suspension test(TST), forced swimming test(FST) and open field test(OPT). A repeated dose of reserpine(0.5 mg/kg, daily for 14 d) was used to establish a rat depression model. Fluoxetine was used as positive control agent. The effect of AFPR on reserpine-induced ptosis, hypothermia and akinesia, the levels of monoamines and their metabolites, and the activity of monoamine oxidase(MAO) in hippocampus and prefrontal cortex were determined.RESULTS: Administration of AFPR by gavage at 160 and 320 mg/kg significantly reduced the duration of immobility in the FST and TST, and did not affect locomotor activity in the OPT. In the reserpine-induced depression model, AFPR attenuated anhedonia, demonstrated by reversing hypothermia, akinesia and sucrose consumption. AFPR significantly increased the concentration of monoamines, including dopamine, serotonin, noradrenaline and acetylcholine.CONCLUSION: AFPR normalized the metabolism rates of noradrenaline, serotonin and dopamine,and the activity of MAO, which were altered by chronic reserpine exposure. The findings suggest that modulation of the monoaminergic neurotransmitter system likely underlies the antidepressant-like effect of AFPR. | Wei Guining Chu Shifeng Su Qibiao Su Hua Lin Meiyu He Fei Lu Wenjie Lu Guoshou Huang Zhoufeng Tan Xiao Lin Xiao Zeng Xianbiao Wei Baowei Chen Naihong | 2018 | Journal of Traditional Chinese Medicine2018,38,1: | 4 |
| 2 | Genomic evidence of lung carcinogenesis associated with coal smoke in Xuanwei area, China显示文摘Xuanwei area, in southwestern China,harbors the highest female lung cancer rate in the country(Supplementary Table 1) [1]. Epidemiological studies have shown that lung cancer incidence in Xuanwei area is associated with the use of different types of local coal for household cooking and heating [2]. The genomic landscape of Xuanwei female adenocarcinoma(XWFA), the most distinctive feature of lung cancer in Xuanwei, has yet to be elucidated systematically. Here,we provide the fundamental resource of genomic datasets for further exploration of XWFA molecular mechanisms and development of targetable therapy. | Honglei Zhang Chao Liu Li Li Xu Feng Qing Wang Jihua Li Shaobin Xu Shuting Wang Qianlu Yang Zhenghai Shen Jinhua Su Xiaosan Su Ruifen Sun Xuhong Zhou Junliang Wang Yongchun Zhou Baowei Jiao Wanbao Ding Xianbao Cao Yue Wang Yunchao Huang Lianhua Ye | 2021 | National Science Review2021,8,12: | 2 |
| 3 | The performance of polyamide nano?ltration membrane for long-term operation inan integrated membrane seawater pretreatment system显示文摘 | Yuefei Song Baowei Su XueliGao | 2012 | Desalination2012,296,: | 1 |
| 4 | Study on seawater manofiltration softening technology for offshore oilfleld water and polymer flooding 显示文摘 | Su Baowei Don aowei Gao Xueli | 2012 | Desalination2012,297,3: | 1 |
| 5 | Plasma vaspin concentrations are decreased in acute coronary syndrome, but unchanged in patients without coronary lesions显示文摘 | Baowei Zhang Wenhui Peng Hailing Li Yuyan Lu Jianhui Zhuang Ke Wang Yang Su Yawei Xu | 2013 | Clinical Biochemistry2013,,: | 1 |
| 6 | The performance of polyamide nanofiltration membrane for long-term operation in an integrated membrane seawater pretreatment system显示文摘 | Yuefei Song Baowei Su Xueli Gao Congjie Gao | 2012 | Desalination2012,,: | 1 |
| 7 | Robust adaptive beamforming via virtual array transformation显示文摘 | Su Baowei Wang Yongliang Zhou Liangzhu | 2005 | IEEE AP S International Symposium on Antennas and Propagation2005,1,7: | 1 |
| 8 | Effect of N_(2)and Ar on CO_(2)conversion with segmented micro-plasma reactor显示文摘The increase of CO_(2)concentration in the atmosphere has brought serious greenhouse effects and environmental problems,so it is urgent to solve the problem of excessive CO_(2)concentration.The carbon capture,utilization,and storage technology refer to the use of CO_(2)as a C_(1)resource to generate new economic benefits in a new production process.In this work,the influence of adding different proportions of N_(2)and Ar to the CO_(2)gas on the discharge characteristics and reaction performance was investigated with a newly designed dielectric barrier discharge(DBD)micro-plasma segmented electrode reactor and optical emission spectroscopy.The results indicated that the discharge current value increased when the added N_(2)content was less than 50%,and decreased when the N_(2)content exceeded 50%under the condition of constant input power.The number and the current value of mixed gas micro-discharges showed a decreasing trend with the increase of Ar content.In the discharge system,the dielectric capacitance(C_(d))and the gas gap capacitance(C_(g))showed opposite trends with the increase of N_(2)and Ar content.The dielectric capacitance decreased and the gas gap capacitance increased as the N_(2)content increased,while the trend was just the opposite as the Ar content increased.In addition,adding a small amount of N_(2)and Ar was conducive to the conversion of CO_(2),but when the N_(2)and Ar content exceeded 50%,the amount of CO_(2)converted will be reduced. | Baowei Wang Xiaoyan Li Xiaoxi Wang Huijuan Su Bo Zhang | 2021 | Waste Disposal and Sustainable Energy2021,3,4: | 0 |