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您的检索式：作者名="SumioWatanabe"
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| 1 | Safety of immediate endoscopic sphincterotomy in acutesuppurative cholangitis caused by choledocholithiasis显示文摘AIM: To examine the safety of immediate endoscopic sphincterotomy(EST) in patients with acute suppurative cholangitis(ASC) caused by choledocholithiasis, as compared with elective EST.METHODS: Patients with ASC due to choledocholithiasis were allocated to two groups: Those who underwent EST immediately and those who underwent EBD followed by EST 1 wk later because they were under anticoagulant therapy, had a coagulopathy(international normalized ratio > 1.3, partial thromboplastin time greater than twice that of control), or had a platelet count < 50000 × 103/μL. One of four trainees [200-400 cases of endoscopic retrograde cholangiopancreatography(ERCP)] supervised by a specialist(> 10000 cases of ERCP) performed the procedures. The success and complication rates associated with EST in each group were examined.RESULTS: Of the 87 patients with ASC, 59 were in the immediate EST group and 28 in the elective EST group. EST was successful in all patients in both groups. There were no complications associated with EST in either group of patients, although white blood cell count, C-reactiveprotein, total bilirubin, and serum concentrations of liver enzymes just before EST were significantly higher in the immediate EST group than in the elective EST group.CONCLUSION: Immediate EST can be as safe as elective EST for patients with ASC associated with choledocholithiasis provided they are not under anticoagulant therapy, or do not have a coagulopathy or a platelet count < 50000 × 103/μL. Moreover, the procedure was safely performed by a trainee under the supervision of an experienced specialist. | Tomoyasu Ito Jin Kan Sai Hironao Okubo Hiroaki Saito Shigeto Ishii Ryo Kanazawa Ko Tomishima SumioWatanabe Shuichiro Shiina | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，3： | 10 |
| 2 | Attenuation of gastric mucosal inflammation induced by aspirin through activation of A_(2A) adenosine receptor in rats显示文摘瞄准:决定特定的腺苷 A (2A ) 受体收缩筋(ATL-146e ) 是否能改善在老鼠的导致阿司匹林的胃的粘膜损害,和还原剂 neutrophil 累积和支持 inflammatory cytokines.METHODS 的生产:胃的损害被阿司匹林(200 mg/kg ) 和 HCl 的口头的管饲法生产(0.15 mol/L, 8.0 mL/kg ) 。4-{3-[6-Amino-9-(5-ethylcarbamoyl-3,4-dihydroxy-tetrahydro-furan-2-yl )-9H- purin-2-yl ]-prop-2-ynyl}-cyclohexanecarboxylic 酸甲基酉旨(ATL-146e, 2.5-5 mug/kg, IP ) 被注射在阿司匹林的管理前的 30 min。在胃粘膜的织物 myeloperoxidase (军邮局) 集中作为嗜中性的渗入的一个索引被测量。肿瘤坏死 factor-alpha (TNF-alpha ) 和 interleukin-1beta (IL-1beta ) 的胃的粘膜集中被 ELISA 决定。另外,我们在织物上检验了 ATL-146e 的效果前列腺素E-2(PGE2 ) 生产和胃的 secretion.RESULTS:阿司匹林的胃内管理在老鼠胃粘膜导致了多重出血性的侵蚀。在控制老鼠的胃的侵蚀(溃疡索引) 的全部的长度是 29.8+/-7.75 公里并且与 5.0 g/kg ATL-146e (P<0.01 ) 在预告的处理以后被归结为 3.8+/-1.42 公里。军邮局和支持 inflammatory cytokines 的胃的内容都在阿司匹林的管理以后被增加并且由 ATL-146e 归结为将近正常的层次。胃的粘膜 PGE2 集中没被 ATL-146e.CONCLUSION 的腹膜内注射影响:特定的腺苷 A (2A ) 受体收缩筋, ATL-146e,有势力反溃疡效果大概由它的反煽动性的性质调停了。 | MasaruOdashima MichiroOtaka MarioJin KogaKomatsu IsaoWada YouheiHorikawa TamotsuMatsuhashi NatsumiHatakeyama JinkoOyake ReinaOhba SumioWatanabe Joel Linden | 2006 | World Journal of Gastroenterology2006，12，4： | 5 |
| 3 | Non‐alcoholic steatohepatitis and hepatocellular carcinoma: Lessons from hepatocyte‐specific phosphatase and tensin homolog (PTEN)‐deficient mice显示文摘 | SumioWatanabe YasuoHorie EiKataoka WataruSato TakahiroDohmen ShigetoshiOhshima TakashiGoto AkiraSuzuki | 2007 | Journal of Gastroenterology and Hepatology2007，，： | 1 |
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