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| 1 | The Right to a Healthy Life or the Right to Die Polluted?: The Emergence of a Human Right to a Healthy Environ- ment Under International Law显示文摘 | SUMUDU A | 2002 | Tulane Environmental Law Journal2002,,16: | 1 |
| 2 | The total number of lymph nodes harvested is associated with better survival in stages II and III colorectal cancer显示文摘 | Pramodh Chitral Chandrasinghe Dileepa Senajith Ediriweera Janaki Hewavisenthi Sumudu Kumarage Kemal Ismail Deen | 2014 | Indian Journal of Gastroenterology2014,,3: | 1 |
| 3 | Duodenum-preserving local excision of a gastrointestinal stromal tumor显示文摘BACKGROUND:Duodenal gastrointestinal stromal tumors (GISTs) are rare. Because of the complex anatomy of the duodenum, the methods of resection of these tumors are controversial and diverse. METHODS:We report a case of a duodenal GIST in the anterolateral wall of the second part of the duodenum, which was successfully managed by local excision. The surgery was facilitated by preoperative mapping with Indian ink and navigation by endoscopy to assess the adequacy of resection and to avoid injury to the ampulla. RESULT:Reconstruction was successful with a duodeno-jejunostomy and protected by a nasoduodenal drain. CONCLUSION:The patient had no postoperative complications and the tumor was confirmed to be a GIST of the duodenum successful with an adequate resection margin. | Chandika AH Liyanage Sanjaya Abeygunawardhana Sumudu Kumarage Kemal I Deen | 2008 | Hepatobiliary & Pancreatic Diseases International2008,7,2: | 1 |
| 4 | Fetal programming of obesity and type 2 diabetes显示文摘The prevalence of obesity and type 2 diabetes mellitus has increased rapidly over the past few decades,and prevention efforts have not been successful.Fetal programming involves the earliest stage of obesity development,and provides a novel concept to complement other strategies for lifelong prevention of obesity and type 2 diabetes mellitus.The World Health Organization now advocates a life-course approach to prevent/control obesity,starting with pre-conceptional and antenatal maternal health.Maternal overnutrition,gestational diabetes mellitus and excessive gestational weight gain lead to fetal overgrowth,and“programs”the offspring with an increased risk of obesity and type 2 diabetes mellitus in childhood and adulthood.This review summarizes current data on fetal programming of obesity and type 2 diabetes mellitus including potential causative factors,mechanisms and interventions to reduce its impact. | Sumudu Nimali Seneviratne Shaman Rajindrajith | 2022 | World Journal of Diabetes2022,13,7: | 0 |
| 5 | On the potential of documenting decadal-scale avifaunal change from before-and-after comparisons of museum and observational data across North America显示文摘Studies of biodiversity dynamics have been cast on either long(systematics)or short(ecology)time scales,leaving a gap in coverage for moderate time scales of decades to centuries.Large-scale biodiversity information resources now available offer opportunities to fill this gap for many parts of the world via detailed,quantitative comparisons of assemblage composition,particularly for regions without rich time series datasets.We explore the possibility that such changes in avifaunas across the United States and Canada before and after the first three decades of marked global change(i.e.,prior to 1980 versus after 2010)can be reconstructed and characterized from existing primary biodiversity data.As an illustration of the potential of this methodology for sites even in regions not as well sampled as the United States and Canada,we also explored changes at a single site in Mexico(Chichén-Itzá).We analyzed two large-scale datasets:one summarizing bird records in the United States and Canada before 1980,and one for the same region after 2010.We used probabilistic inventory completeness analyses to identify sites that have avifaunas that have likely been inventoried more or less completely.We prepared detailed comparisons between the two time periods to analyze species showing distributional changes over the time period analyzed.We identified 139 sites on a 0.05°grid that were demonstrably well-inventoried before 1980 in the United States and Canada,of which 108 were also well-inventoried after 2010.Comparing presence/absence patterns between the two time periods for 601 bird species,we found significant spatial autocorrelation in overall avifaunal turnover(species gained and lost),but not in numbers of species lost.We noted potential northward retractions of ranges of several species with high-latitude(boreal)distributions,while other species showed dominant patterns of population loss,either rangewide(e.g.,Tympanuchus cupido)or regionally(e.g.,Thryomanes bewickii).We developed linear models to explore a suite of potential drivers of species loss at relatively fine-grained resolutions(<6km),finding significant effects of precipitation increase,particularly on the eastern border of the United States and Canada.Our exploration of biotic change in Chichén-Itzáincluded 265 species and showed intriguing losses from the local avifauna(e.g.,Patagioenas speciosa),as well as vagrant and recent invasive species in the Yucatán Peninsula.The present work documents both the potential for and the problems involved in an approach integrating primary biodiversity data across time periods.This method potentially allows researchers to assess intermediate-time-scale biodiversity dynamics that can reveal patterns of change in biodiversity-rich regions that lack extensive time-series information. | Fernando Machado-Stredel Benedictus Freeman Daniel Jiménez-Garcia Marlon E.Cobos Claudia Nunez-Penichet Laura Jiménez Ed Komp Utku Perktas Ali Khalighifar Kate Ingenloff Walter Tapondjou Thilina de Silva Sumudu Fernando Luis Osorio-Olvera A.Townsend Peterson | 2022 | Avian Research2022,13,1: | 0 |
| 6 | Proximal and distal rectal cancers differ in curative resectability and local recurrence显示文摘AIM: To evaluate patients with proximal rectal cancer (PRC) (> 6 cm up to 12 cm) and distal rectal cancer (DRC) (0 to 6 cm from the anal verge). METHODS: Two hundred and eighteen patients (120 male, 98 female, median age 58 years, range 19-88 years) comprised 100 with PRC and 118 with DRC. The proportion of T1, T2 vs T3, T4 stage cancers was similar in both groups (PRC: T1+T2 = 29%; T3+T4 = 71% and DRC: T1+T2 = -31%; T3+T4 = 69%). All patients had cancer confined to the rectum -those with synchronous distant metastasis were excluded. Surgical resection was with curative intent with or without pre-operative chemoradiation (c-RT). Follow-up was for a median of 35 mo (range: 12 to 126 mo). End points were: 30 d mortality, complications of operation, microscopic tumour-free margins, resection with a tumour-free circumferential margin (CRM) of 1 to 2 mm and > 2 mm, local recurrence, survival and the permanent stoma rate. RESULTS: Overall 30-d mortality was 6% (12): PRC 7 % and DRC 4%. Postoperative complications occurred in 14% with PRC compared with 21.5% with DRC, urinary retention was the complication most frequently reported (PRC 2% vs DRC 9%, P = 0.04). Twelve percent with PRC compared with 37% with DRC were subjected to preoperative c-RT (P = 0.03). A tumour-free CRM of 1 to 2 mm and > 2 mm was reported in 93% and 82% with PRC and 88% and 75% with DRC respectively (PRC vs DRC, P > 0.05). However, local recurrence was 5% for PRC vs 11% for DRC (P < 0.001). Three and five years survival was 65.6% and 60.2% for PRC vs 67% and 64.3% for DRC respectively. No patient with PRC and 23 (20%) with DRC received an abdomino-perineal resection. CONCLUSION: PRC and DRC differ in the rate of abdomino-perineal resection, post-operative urinary retention and local recurrence. Survival in both groups was similar. | Wasantha Wijenayake Mahendra Perera Jayantha Balawardena Raeed Deen S Ruwan Wijesuriya Sumudu K Kumarage Kemal I Deen | 2011 | World Journal of Gastrointestinal Surgery2011,3,8: | 0 |