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| 1 | Gait analysis of patients with knee osteoarthritis before and after Chinese massage treatment显示文摘The objective of this study was to evaluate the effectiveness of Chinese massage therapy in patients with knee osteoarthritis(OA) by measuring lower-limb gait parameters. We recruited 20 women with knee OA,who then underwent Chinese massage therapy three times per week for 2 weeks. The patients underwent gait evaluation using a six-camera infrared motion analysis system. They completed Western Ontario and Mc Master Universities Osteoarthritis Index questionnaires before and after treatment. We calculated the forward speed,step width,step length,total support time percentage,initial double support time percentage,and single support time percentage. We also measured the angles at the knee,hip,and ankle during the stance phase of walking. The results showed statistically significant mean differences in knee pain relief,alleviation of stiffness,and physical function enhancement after therapy(P < 0.05). The patients gained significantly faster gait speed,greater step width,and increased total support time percentage after the Chinese massage therapy(P < 0.05). There were no significant differences in the range of motion or initial contact angles of the knee,hip,or ankle during the stance phase of walking. We concluded that Chinese massage is a beneficial complementary treatment and an alternative therapy choice for patients with knee OA for short-term pain relief. Chinese massage may improve walking ability for these patients. | Zhu Qingguang Fang Min Gong Li Jiang Shuyun Sun Wuquan Li Jianhua Li Yong | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 16 |
| 2 | Effect of Chinese massage(Tui Na) on isokinetic muscle strength in patients with knee osteoarthritis显示文摘OBJECTIVE: Chinese massage(Tui Na) is one of the most popular Traditional Chinese Medicine remedies for knee osteoarthritis(OA). Several studies have subjectively evaluated the effect of Chinese massage on knee OA through self-assessment questionnaires; however, very few studies have objectively assessed the effect by measuring knee muscle strength. The purpose of this study was to assess the efficacy of Chinese massage in improving knee extensor and flexor muscle strength in patients with knee OA.METHODS: Thirty patients with knee OA received Chinese massage therapy three times per week for 2 weeks. Patients completed pre- and post-treatment Visual Analogue Scale(VAS) pain questionnaires, and pre- and post-treatment knee muscle strength was evaluated using the Biodex Multi-Joint System 3. Isokinetic muscle strength measurements were performed at 60 degrees/s and 180 degrees/s. The peak torque(PT), peak torque/body weight(PT/BW), total work(TW), average power(AP), hamstring/quadriceps(H/Q), and range of motion(ROM) values were recorded separately for flexors and extensors.RESULTS: Chinese massage therapy significantly improved knee pain as assessed by the VAS in patients with knee OA(P < 0.05). Post-treatment values were significantly greater than pre-treatment values in the extensor muscles for PT(right P =0.013, left P = 0.001), PT/BW(right P = 0.008, left P =0.001) and TW(right P = 0.036, left P = 0.004) at 60 degrees/s. The AP increased significantly after treatment in the flexor muscles in the right knee(P =0.009) and the extensor muscles in the left knee(P = 0.001). There were no significant differences in pre- and post-treatment ROM and H/Q at 60 degrees/s and 180 degrees/s.CONCLUSION: Chinese massage therapy decreased pain and may improve extensor muscle strength in patients with knee OA, but does not appear to improve ROM. | Zhu Qingguang Li Jianhua Fang Min Gong Li Sun Wuquan Zhou Nan | 2016 | Journal of Traditional Chinese Medicine2016，36，3： | 13 |
| 3 | Possible mechanism underlying analgesic effect of Tuina in rats may involve piezo mechanosensitive channels within dorsal root ganglia axon显示文摘OBJECTIVE: To demonstrate the analgesic effect of Tuina mainly from mechanically sensitive ion channels in peripheral myelinated nerve fibers.METHODS: A total of 40 healthy and pathogen-free adult male Sprague-Dawley rats were used in the study [weight:(220.0 ± 1.4) g, Shanghai Slac Laboratory Animal Co., Ltd., Shanghai, China; license No. Shanghai ICP 05033115]. The rats were housed in cages with free access to water and food in a temperature-controlled room [(22 ± 1) ℃] and12-h/12-h light-dark cycle. Thirty-two rats were randomly divided into five groups: naive, sham, chronic compression of dorsal root ganglion(CCD), Tuina(7 d) and Tuina(21 d). CCD rat model was established via unilateral DRG compression by'L'liked steel bar. Chinese Tuina treatment was accepted once per day. Behavior monitoring of paw withdrawal threshold(PWT) and paw withdrawal latency(PWL) were tested. The expression of Piezo1 and Piezo2 in myelinated nerve fiber were analyzed by immunohistochemistry and Western-blotting.RESULTS: There was a high expression of Piezo2 and a low expression of Piezo1 in the naive and CCD groups. In contrast, the expression of Piezo2 was down regulated and Piezo1 was increased after a period of Tuina. There was significant difference(P ≤ 0.05) between the groups.CONCLUSION: Our findings suggest that Tuina therapy can increase the expression of Piezo2 and decrease the expression of Piezo1 in the test rats.The different changes in the expressions of Piezo1 and Piezo2 may play an important role in alleviating CCD-induced allodynia and hyperalgesia. | Song Pengfei Lin Zhigang Zhu Qingguang Jiang Shichao Zhang Hao Cheng Yanbin Sun Wuquan Wu Zhiwei Zhou Xin Lv Zhizhen Fang Min | 2018 | Journal of Traditional Chinese Medicine2018，38，6： | 6 |
| 4 | Effectiveness of Liu-zi-jue exercise on coronavirus disease 2019 in the patients: a randomized controlled trial显示文摘OBJECTIVE: The aim of this study was to examine the effect of Liu-zi-jue exercise on the respiratory symptoms, quality of life, and mental health of patients with mild coronavirus disease 2019(COVID-19). METHODS: A single-center randomized controlled trial was conducted with 104 patients with mild COVID-19. The patients were randomly assigned to the Liu-zi-jue plus conventional therapy group and conventional therapy group. The outcome measures included Modified Borg Dyspnea Scale(MBDS) score, Patient Health Questionnaire-9(PHQ-9) score, Fatigue Scale-14(FS-14), respiratory symptoms, and vital signs. Data were collected on the first and sixth days of hospitalization and on the discharge day. RESULTS: Repeated-measures ANOVA revealed that the whole scales all showed a downward trend in the two groups(all P < 0.05). The results of single-group effect suggested that the whole scale score in the intervention group was significantly lower than that in the control group at the sixth day of hospitalization. Compared with the control group, only the MBDS, expectoration, and FS-14 scores showed significantly lower scores at the discharge day(P < 0.001, P = 0.011, P = 0.002). Comparison within the group showed that all the variables were significantly different at the three time points with a decreasing trend(P < 0.05), except for the PHQ-9 and expectoration scores(P = 0.331, 0.052). All patients’ vital signs remained within a stable normal range throughout the hospital stay. CONCLUSION: The results suggested that Liu-zi-jue exercise as a complementary and alternative therapy showed beneficial effects on improving the symptoms(shortness of breath, fatigue, and cough), quality of life, and mental health of patients with mild COVID-19. | ZHU Qingguang ZHANG Shuaipan LI Jingxian SUN Wuquan CHENG Wei ZHAN Chao CHENG Yanbin FANG Lei FANG Min | 2022 | Journal of Traditional Chinese Medicine2022，42，6： | 1 |
| 5 | The therapeutic efficacy of glutamine for rats with smoking inhalation injury显示文摘 | Wuquan Li Xiaochen Qiu Junjie Wang Hengyu Li Yu Sun Fang Zhang Haichao Jin Jinfeng Fu Zhaofan Xia | 2013 | International Immunopharmacology2013，，2： | 1 |
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