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2篇 您的检索式：作者名="Sungsu Lim"

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		题名	作者	年代	出处	被引量
	1	Picomolar-sensitiveβ-amyloid fibril fluorophores by tailoring the hydrophobicity of biannulatedπ-elongated dioxaborine-dyes显示文摘The pathological origin of Alzheimer’s disease(AD)is still shrouded in mystery,despite intensive worldwide research efforts.The selective visualization ofβ-amyloid(Aβ),the most abundant proteinaceous deposit in AD,is pivotal to reveal AD pathology.To date,several small-molecule fluorophores for Aβspecies have been developed,with increasing binding affinities.In the current work,two organic small-molecule dioxaborine-derived fluorophores were rationally designed through tailoring the hydrophobicity with the aim to enhance the binding affinity for Aβ_(1-42) fibrils-while concurrently preventing poor aqueous solubility-via biannulate donor motifs in D-π-A dyes.An unprecedented sub-nanomolar affinity was found(K_(d)=0.62±0.33 nM)and applied to super-sensitive and red-emissive fluorescent staining of amyloid plaques in cortical brain tissue ex vivo.These fluorophores expand the dioxaborine-curcumin-based family of Aβ-sensitive fluorophores with a promising new imaging agent.	Jusung An Peter Verwilst Hira Aziz Jinwoo Shin Sungsu Lim Ilwha Kim Yun Kyung Kim Jong Seung Kim	2022	Bioactive Materials2022，7，7：	1
	2	Nanobubble Dynamics in Aqueous Surfactant Solutions Studied by Liquid-Phase Transmission Electron Microscopy显示文摘Nanobubbles have attracted considerable attention in various industrial applications due to their exceptionally long lifetime and their potential as carriers at the nanoscale.The stability and physiochemical properties of nanobubbles are highly sensitive to the presence of surfactants that can lower their surface tension or improve their electrostatic stabilization.Herein,we report real-time observations of the dynamic behaviors of nanobubbles in the presence of soluble surfactants.Using liquid-phase transmission electron microscopy(TEM)with multi-chamber graphene liquid cells,bulk nanobubbles and surface nanobubbles were observed in the same imaging condition.Our direct observations of nanobubbles indicate that stable gas transport frequently occurs without interfaces merging,while a narrow distance is maintained between the interfaces of interacting surfactant-laden nanobubbles.Our results also elucidate that the interface curvature of nanobubbles is an important factor that determines their interfacial stability.	Yuna Bae Sungsu Kang Byung Hyo Kim Kitaek Lim Sungho Jeon Sangdeok Shim Won Chul Lee Jungwon Park	2021	Engineering2021，7，5：	0

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