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| 1 | Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors显示文摘Long non-coding RNAs(lncRNAs)are members of the non-protein coding RNA family longer than 200 nucleotides.They participate in the regulation of gene and protein expression influencing apoptosis,cell proliferation and immune responses,thereby playing a critical role in the development and progression of various cancers,including colorectal cancer(CRC).As CRC is one of the most frequently diagnosed malignancies worldwide with high mortality,its screening and early detection are crucial,so the identification of disease-specific biomarkers is necessary.LncRNAs are promising candidates as they are involved in carcinogenesis,and certain lncRNAs(e.g.,CCAT1,CRNDE,CRCAL1-4)show altered expression in adenomas,making them potential early diagnostic markers.In addition to being useful as tissue-specific markers,analysis of circulating lncRNAs(e.g.,CCAT1,CCAT2,BLACAT1,CRNDE,NEAT1,UCA1)in peripheral blood offers the possibility to establish minimally invasive,liquid biopsy-based diagnostic tests.This review article aims to describe the origin,structure,and functions of lncRNAs and to discuss their contribution to CRC development.Moreover,our purpose is to summarise lncRNAs showing altered expression levels during tumor formation in both colon tissue and plasma/serum samples and to demonstrate their clinical implications as diagnostic or prognostic biomarkers for CRC. | Orsolya Galamb Barbara K Barták Alexandra Kalmár Zsófia B Nagy Krisztina A Szigeti Zsolt Tulassay Peter Igaz Béla Molnár | 2019 | World Journal of Gastroenterology2019，25，34： | 18 |
| 2 | 评估清晨或夜晚服用降压药对24h动态血压的影响:清晨或夜间服用降压药的希腊英国联合研究显示文摘观察数据显示,临床血压水平与随后的主要不良心血管事件之间存在强烈的线性关系。然而,动态血压监测显示,夜间血压水平比24h或白天血压水平更能预测主要的不良心血管事件。此外,夜间与白天的血压比值和杓型状态也是心血管结局的重要独立预测因素。这些发现可能对抗高血压药物的最佳给药时间有影响,一些研究表明,夜晚服用降压药可能较白天服药减少心血管事件。 | Poulter NR Savopoulos C Anjum A Apostolopoulou M Chapman N Cross M Falaschetti E Fotiadis S James RM Kanellos I Szigeti M Thom S Sever P Thompson D Hatzitolios AI 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，10： | 7 |
| 3 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013，，2： | 2 |
| 4 | Preliminary study of TIP47 as a possible new biomarker of cervical dysplasia and invasive carcinoma显示文摘 | Szigeti A Minik O Hocsak E | 2009 | Anticancer Res2009，29，2： | 1 |
| 5 | Nicotine interferes with purinergic signaling in smooth muscle cells isolated from uri- nary bladders of patients with lower urinary tract symptoms 显示文摘 | Jenes A Szigeti GP Ruzsnavszky F | 2013 | Gen Physiol Biophys2013，32，： | 1 |
| 6 | Impact of iron supply on the kinetics of recovery of photosynthesis in Cd-stressed Poplar (Populus glauca) 显示文摘 | Solti A Gaspar L Szigeti Z | 2008 | Annals of botany2008，102，5： | 1 |
| 7 | Correlation of prenatal sonographic diagnosis and morphologic findings of fetal autop- sy in fetuses with trisomy 21显示文摘 | Szigeti Z Csaba A Pete B | 2007 | Journal of Ultrasound in Medicine2007，26，1： | 1 |
| 8 | A morphological study of retinal changes in unilateral amblyopia using optical coherence tomography image segmentation 显示文摘 | Szigeti A Tatrai E Szamosi A | 2014 | PLoS One2014，9，88： | 1 |
| 9 | Facilitation of mitochon- drial outer and inner membrane permeabilization and cell death in oxidative stress by a novel Bcl-2 homology 3 domain protein 显示文摘 | Szigeti A Hocsak E Rapohi E | 2010 | J Biol Chem2010，256，3： | 1 |
| 10 | Correlation of prenatal sonographic diagnosis and morphologic fingings of fetal autopsy in fetuses with trisomy 21 显示文摘 | Szigeti Z Csaba A Pete B | 2007 | J Ultrasound Med2007，26，1： | 1 |
| 11 | Correlation of prenatal sonographic diagnosis and morphologic findings of fetal autopsyin fetuses with trisomy 21显示文摘 | Szigeti Z Csaba A Pete B | | 0，，01： | 1 |
| 12 | Robust detection filter design in the presence of time varying system perturbations 显示文摘 | EDELMAYER A BOKOR J SZIGETI F | 1997 | Automatica1997，33，5： | 1 |
| 13 | Correlation of prenatal sonographic diagnosis and morphologic findings of fetal autopsy in fetuses with trisomy 21显示文摘 | Szigeti Z Csaba A Pete B | 2007 | J Ultrasound Med2007，26，1： | 1 |
| 14 | Preventing apoptotic cell death by a novel small heat shock protein显示文摘 | Bellyei S Szigeti A Pozsgai E | 2007 | Eur J Cell Biol2007，86，6： | 1 |
| 15 | The Effect of Axial Length on the Thickness of Intraretinal Layers of the Macula显示文摘 | Szigeti A Tatrai E Varga BE | 2015 | PloS one2015，10，01： | 1 |
| 16 | Facilitation of mitochondrlal outer and inner membrane permeabilization and cell death in oxidative stress by a novel Bcl-2 homology 3 domain protein 显示文摘 | SZIGETI A HOCSAK E RAPOLTI E | 2010 | J Biol Chem2010，285，： | 1 |
| 17 | Laser refractive cataract surgery with a femtosecond laser af- ter penetrating keratoplasty: case report 显示文摘 | Nagy ZZ TakOcs AI Filkorn T JuhOsz t S6ndor G Szigeti A | 2013 | J Refract Surg2013，29，1： | 1 |
| 18 | ABCG2 is a selectable marker for enhanced multilineage differentiation potential in periodontal ligament stemcells显示文摘 | Szepesi A Matula Z Szigeti A | 2015 | Stem Cells Dev2015，24，2： | 1 |
| 19 | Correlation of prenatal sonographic diagnosis and morphologic findings of fetal autopsyin fetuses with trisomy 21 显示文摘 | Szigeti Z Csaba A Pete B | 2007 | J Ultrasound Med2007，26，1： | 1 |
| 20 | Robust detection filter design in the presence of time varying system perturbations 显示文摘 | EDELMAYER A BOKOR J SZIGETI F | 1997 | Automatics1997，，3： | 1 |
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