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| 1 | Autoantibody profiles in autoimmune hepatitis and chronic hepatitis C identifies similarities in patients with severe disease显示文摘AIM To determine how the auto-antibodies(Abs) profiles overlap in chronic hepatitis C infection(CHC) and autoimmune hepatitis(AIH) and correlate to liver disease.METHODS Levels of antinuclear Ab, smooth muscle antibody(SMA) and liver/kidney microsomal-1(LKM-1) Ab and markers of liver damage were determined in the sera of 50 patients with CHC infection, 20 AIH patients and 20 healthy controls using enzyme linked immunosorbent assay and other immune assays. RESULTS We found that AIH patients had more severe liver disease as determined by elevation of total Ig G, alkaline phosphatase, total serum bilirubin and serum transaminases and significantly higher prevalence of the three non-organ-specific autoantibodies(auto-Abs) than CHC patients. Antinuclear Ab, SMA and LKM-1 Ab were also present in 36% of CHC patients and related to disease severity. CHC cases positive for auto-Abs were directly comparable to AIH in respect of most markers of liver damage and total Ig G. These cases had longer disease duration compared with auto-Ab negative cases, but there was no difference in gender, age or viral load. KLM-1+ Ab CHC cases showed best overlap with AIH. CONCLUSION Auto-Ab levels in CHC may be important markers of disease severity and positive cases have a disease similar to AIH. Auto-Abs might have a pathogenic role as indicated by elevated markers of liver damage. Future studies will unravel any novel associations between these two diseases, whether genetic or other. | Kawa Amin Aram H Rasool Ali Hattem Taha AM Al-Karboly Taher E Taher Jonas Bystrom | 2017 | World Journal of Gastroenterology2017，23，8： | 5 |
| 2 | Steinstrasse after extracorporeal shockwave lithotripsy: eatiology, prevention and management显示文摘 | SAYED MA TAHER AM ABOUL-ELLA HA | 2001 | BUJ Int2001，88，7： | 1 |
| 3 | Locally advanced rectal carcinoma : preoperative radiotherapy versus postoperate chemoradiation, 10-year followed-up results of a randomizedclinical study显示文摘 | Taher AN E1-Baradie MM Nasr AM | 2006 | Egyp Natl Cane Inst2006，18，3： | 1 |
| 4 | Cyclin D1 gene amplification in proliferating haemangioma显示文摘 | Mohamed AM Elwakil TF Taher IM | | 0，，01： | 1 |
| 5 | Pituitary enlargement in patients with primary hypothyroidism显示文摘 | Khawaja NM Taher BM Barham ME Naser AA Hadidy AM Ahmad AT | 2006 | Endoer Pract2006，12，1： | 1 |
| 6 | The genome of the Western clawed frog Xenopus tropicalis显示文摘 | Hellsten U Harland R M Gilchrist M J Hendrix D Jurka J Kapitonov V Ovcharenko I Putnam N H Shu S Taher L Blitz I L Blumberg B Dichmann D S Dubchak I Amaya E Detter J C Fletcher R Gerhard D S Goodstein D Graves T Grigoriev I V Grimwood J Kawashima T Lindquist E Lucas S M Mead P E Mitros T Ogino H Ohta Y Poliakov A V Pollet N Robert J Salamov A Sater A K Schmutz J Terry A Vize P D Warren W C Wells D Wills A Wilson R K Zimmerman L B Zorn AM Grainger R Grammer T Khokha M K Richardson P M Rokhsar D S | 2010 | Science2010，328，5978： | 1 |
| 7 | Menopausal age,related factors and climacteric symptoms in Libyan women显示文摘 | Taher YA1 Ben Emhemed HM Tawati AM | 2013 | Climacteric2013，16，： | 1 |
| 8 | Cyclin DI gene ampli-fication in proliferating haemangioma 显示文摘 | Mohamed AM Elwakil TF Taher IM | 2009 | Cell Tissue Res2009，338，1： | 1 |
| 9 | Locally advanced rectal carcinoma: preoperative radiotherapy versus pestoperate ehemoradi- ation,lO-year folowed-up results of a randomized clinical study显示文摘 | Taher AN EI-Baradie MM Nasr AM | 2006 | Egyp Nal Canc Inst2006，18，3： | 1 |
| 10 | Compara- tive study between I -gel, a new supraglottic airway de- vice, and classical laryngeal mask airway in anesthetized spontaneously ventilated patients 显示文摘 | Atef HM Helmy AM E1 -Taher EM | 2012 | Middle East J Anaesthesiol2012，21，4： | 1 |
| 11 | Management of penile fracture显示文摘 | El -Taher AM Aboul -Ella HA Sayed MA | 2004 | J Trauma2004，56，5： | 1 |
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