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	题名	作者	年代	出处	被引量
1	Regulation of activin receptor-interacting protein 2 expression in mouse hepatoma Hepa1-6 cells and its relationship with collagen type Ⅳ显示文摘AIM: To investigate the regulation of activin receptor-interacting protein 2 (ARIP2) expression and its possible relationships with collagen type Ⅳ (collagen Ⅳ) in mouse hepatoma cell line Hepal-6 cells. METHODS: The ARIP2 mRNA expression kinetics in Hepal-6 cells was detected by RT-PCR,and its regulation factors were analyzed by treatment with signal transduction activators such as phorbol 12-myristate 13-acetate (PMA),forskolin and A23187. After pcDNA3-ARIP2 was transfected into Hepal-6 cells,the effects of ARIP2 overexpression on activin type Ⅱ receptor (ActRⅡ) and collagen Ⅳ expression were evaluated. RESULTS: The expression levels of ARIP2 mRNA in Hapel-6 cells were elevated in time-dependent manner 12 h after treatment with activin A and endotoxin LPS,but not changed evidently in the early stage of stimulation (2 or 4 h). The ARIP2 mRNA expression was increased after stimulated with signal transduction activators such as PMA and forskolin in Hepal-6 cells,whereas decreased after treatment with A23187 (25.3% ± 5.7% vs 48.1% ± 3.6%,P < 0.01). ARIP2 overexpression could remarkably suppress the expression of ActRⅡA mRNA in dose-dependent manner,but has no effect on ActRⅡB in Hepal-6 cells induced by activin A. Furthermore,we have found that overexpression of ARIP2 could inhibit collagen Ⅳ mRNA and protein expressions induced by activin A in Hapel-6 cells. CONCLUSION: These findings suggest that ARIP2 expression can be influenced by various factors. ARIP2 may participate in the negative feedback regulation of signal transduction in the late stage by affecting the expression of ActRⅡA and play an important role in regulation of development of liver fibrosis induced by activin.	Hong-Jun Zhang Gui-Xiang Tai Jing Zhou Di Ma Zhong-Hui Liu	2007	World Journal of Gastroenterology2007，13，41：	14
2	Ultrafine particle emission characteristics of diesel engine by on-board and test bench measurement显示文摘This study investigated the emission characteristics of ultrafine particles based on test bench and on-board measurements. The bench test results showed the ultrafine particle number concentration of the diesel engine to be in the range of (0.56-8.35)×10 8cm-3. The on-board measurement results illustrated that the ultrafine particles were strongly correlated with changes in real-world driving cycles. The particle number concentration was down to 2.0×106cm-3 and 2.7×107cm-3 under decelerating and idling operations and as high as 5.0×108cm-3 under accelerating operation. It was also indicated that the particle number measured by the two methods increased with the growth of engine load at each engine speed in both cases. The particle number presented a 'U' shaped distribution with changing speed at high engine load conditions, which implies that the particle number will reach its lowest level at medium engine speeds. The particle sizes of both measurements showed single mode distributions. The peak of particle size was located at about 50-80nm in the accumulation mode particle range. Nucleation mode particles will significantly increase at low engine load operations like idling and decelerating caused by the high concentration of unburned organic compounds.	Cheng Huang Diming Lou Zhiyuan Hu Piqiang Tai Di Yao Wei Hu Peng Li Jin Ren Changhong Chen	2012	Journal of Environmental Sciences2012，24，11：	8
3	The -251T allele of the intedeu- kin-8 promoter is associated with increased risk of gastric carcino- ma featuring diffuse-type histopathology in Chinese population 显示文摘	Lee WP Tai DI Lan KH	2005	Clin Cancer Res2005，11，：	1
4	Activation of nuclear factor kappa B in hepatitis C virus infection: implications for pathogenesis and hepatocarcino genesis显示文摘	Tai Di Tsai SL Chen YM	2000	Hepatology2000，31，3：	1
5	The development of cirrhosis in patients with chronic type B hepatitis:aprospective study显示文摘	Liaw YF Tai DI Chu CM Chen TJ	1988	Hepatology1988，8，3：	1
6	Prevalence of and risk factors for gallbladder polyps detected by ultrasonograohy among healthy Chinese: analysis of 34 669 cases显示文摘	Lin WR Lin DY Tai DI	2008	J Gastroenterol Hepatol2008，23，6：	1
7	The-251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featur-ing diffuse-type histopathology in Chinese population显示文摘	Lee WP Tai DI Lan KH	2005	Clin Cancer Res2005，11，18：	1
8	Unusually high alanine amino- transferase to aspartate aminotransferase ratio in a patient with cyproterone-induced icteric hepatitis 显示文摘	Hsu YC Tai DI	2012	Chang Gung Med J2012，34，6：	1
9	Eight-year nationwide survival analysisin relatives of patients with hepatocellular carcinoma:role of viral infec-tion显示文摘	Tai DI Chen CH Chang TT	2002	J Gastroenterol Hepatol2002，17，6：	1
10	Enhanced nuclear factor-kappa B-associated Wnt-1 expression in hepatitis B-and C-related hepatocarcinogenesis:identification by functional proteomics显示文摘	Lee TH Tai DI Cheng CJ	2006	J Biomed Sci2006，13，1：	1
11	The development of cirrhosis in patients with chronic type B hepatitis:a prospective study显示文摘	Liaw YF Tai DI Ghu CW		0，，03：	1
12	Natural course after the development of cirrhosis in patients with chronic type B hepatitis:a prospective study显示文摘	Liaw YF Tai DI Chu CW	1989	Liver1989，9，4：	1
13	Eight-year nationwide survival analysis in relatives of patients with hepatocellular carcinoma:role of viral infection显示文摘	Tai DI Chen CH Chang TT	2002	J Gastroenterol Hepatol2002，17，6：	1
14	Liver biochemical tests and dengue fever显示文摘	KUO CH TAI DI CHANG CS	1992	Am J Trop Med Hyg1992，47，3：	1
15	Prevalenceof and risk factors for gallbladder polyps detec- ted by ultrasonography among healthy Chinese : analysis of 34 669 cases 显示文摘	Lin WR Lin DY Tai DI	2008	J Gastroenterol Hepatol2008，23，6：	1
16	Adenovirus type 5 EIA sensitizes hepatocellular carcinoma cells to gemcitabine显示文摘	Lee WP Tai DI Tsai SL	2003	Cancer Res2003，63，19：	1
17	Eight year nationwidesurvival analysis in relatives of patients with hepatocelluarcarcinoma: role of viral infection 显示文摘	Tai DI Chen CH Chang TT ->	2002	J GastroenterolHepatol2002，17，6：	1
18	Prevalence of and risk factors for gallbladder polyps detected by ultrasonography among healthy Chinese: analysis of 34 669 cases 显示文摘	Lin WR Lin DY Tai DI	2008	J Gastroenterol Hepatol2008，23，6：	1
19	Activation of nuclear factor KB in hepatitis C infection : implications for pathogenesis and Hepatocarcinomgenesis显示文摘	Tai DI Tsai SL Chen YM	2000	Hepatology2000，31，3：	1
20	The development of cirrhosis in patients with chronic type B hepatitis:a prospective study显示文摘	Liaw YF Tai DI Chu CW	1988	Hepatology1988，8，：	1

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