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| 1 | Testicular sperm extraction and intracytoplasmic sperm injection in non obstructive azoospermia显示文摘Objective To report the experience in sperm extraction from testicular biopsies (TESE) performed from March 1996 to July 1998 in men with non obstructive azoospermia (NOA) Methods Comparisons of age, volume of both testes, serum FSH and testosterone in men, and histology of testicular samples in the first cycles between cycles with spermatozoa found and those without spermatozoa found were performed Comparisons of fertilization, cleavage and pregnancy rates between cycles with spermatozoa injected and those with spermatids injected were performed Results Spermatozoa were found in only 12 out of 26 first TESE cycles (46 2%) and other cycles had spermatids (round cells) only Age of men, history of mumps orchitis/oligozoospermia, volume of both testes and serum FSH/testosterone levels in men were not significantly different between cycles with and without spermatozoa The fertilization rate was significantly higher in cycles with spermatozoa injected than those with round cell injections (63 3% vs 23 2%, P <0 0001, Chi squared test) The pregnancy rate was 14 3% per cycle when spermatozoa were injected Conclusions TESE followed by Intracytoplasmic sperm injection (ICSI) is an effective treatment in patients with NOA Less than half of the patients undergoing TESE had spermatozoa recovered Age of men, volume of both testes and serum FSH/ testosterone levels in men were not useful in predicting successful recovery Compared to using ejaculated and epididymal spermatozoa, fertilization and pregnancy rates were achieved when testicular spermatozoa were used for | Ng Hung Yu Ernest, Lau Yee Lan, Yeung Shu Biu, So Wai Ki, Tam Po Chor and Ho Pak Chung | 2000 | Chinese Medical Journal2000，，3： | 7 |
| 2 | Association of complement factor H polymorphisms with exudative age-related maeular degeneration 显示文摘 | Chen LJ Liu DT Tam PO | 2006 | Mol Vis2006，12，： | 1 |
| 3 | Genetic markers for retinitis pigmentosa显示文摘 | Wang DY Chan WM Tam PO | 2005 | H ong Kong Med J2005，11，4： | 1 |
| 4 | Gene mutations in retinitis pigmentosa and their clinical implications 显示文摘 | Wang DY Chan WM Tam PO Baum L Lam DS Chong KK | 2005 | Clin Chim Acta2005，351，12： | 1 |
| 5 | An αA-crystallin gene mutation, Arg12Cys, causing inherited cataract-microcornea exhibits an altered heat-shock response 显示文摘 | Zhang LY Yam GH Tam PO | 2009 | Mol Vis2009，15，： | 1 |
| 6 | Hepatitis E virus:identification of type-common epitopes显示文摘 | Tam AW Krawczynski K | 1991 | J Virol1991，65，11： | 1 |
| 7 | Gene mutations in retinitis pigmentosa and their clinical implications显示文摘 | Wang DY Chan WM Tam PO | 2005 | Clin Chim Acta2005，351，： | 1 |
| 8 | A genome-wide scan maps a novel high myopia locus to $plS显示文摘 | LAM CY TAM PO FAN DS | 2008 | Invest Ophtha[mol Vis Sci2008，49，9： | 1 |
| 9 | HTRA1 variants in exudative age-related macular degeneration and interactions with smoking and CFH显示文摘 | Tam PO Ng TK Liu DT | | 0，，06： | 1 |
| 10 | Hepatitis E virus: identification of type-common epitopes 显示文摘 | Tam AW Fry KE | 1991 | Journao of Virology1991，65，： | 1 |
| 11 | Gene mutations in retinitis pigmentosa and their clinical implications显示文摘 | Wang DY Chan WM Tam PO | 2005 | Clin Chim Acta2005，351，1： | 1 |
| 12 | A genome-wide scan maps a novel high myopia locus to 5p15显示文摘 | Lam CY Tam PO Fan DS | | 0，，： | 1 |
| 13 | An alphaA-crystallin gene mutation,Arg12Cys,causing inherited cataract-microcornea exhibits an altered heat-shock response显示文摘 | Zhang LY Yam GH Tam PO | 2009 | Mol Vis2009，15，： | 1 |
| 14 | TGFbeta-induced factor:a candidate gene for high myopia显示文摘 | Lam DS Lee WS Leung YF Tam PO Fan DS Fan BJ | 2003 | Invest Ophthalmol Vis Sci2003，44，3： | 1 |
| 15 | In- corporating passenger perceived service quality in airport ground access mode choice model ]显示文摘 | Mei Ling Tam William H K Lam Hing Po Lo | 2010 | Transportmetrica2010，6，1： | 1 |
| 16 | In vitro infectionand replication of hepatitis E virus in primarycynomolgus ma-caque hepatocytes显示文摘 | Tam AW White R Yarbough PO | 1997 | Virology1997，238，1： | 1 |
| 17 | Association of complement factor H polymorphisms with exudative age-related macular degeneration 显示文摘 | Ghen LJ Liu DT Tam PO | 2006 | Mol Vis2006，12，： | 1 |
| 18 | Absence of myocilin and optineurin mutations in a large Philippine family with juvenile onset primary open angle glaucoma显示文摘 | Wang DY Fan BJ Canlas O Tam PO Ritch R Lam DS | 2004 | Mol Vis2004，10，： | 1 |
| 19 | In vitro infection and replication of hepatitis E virus in primary cynomolgus macaque hep- atoeytes显示文摘 | Tam AW White R Yarbough PO | 1997 | Virology1997，238，1： | 1 |
| 20 | High-throughput conformation-sensitive gel electrophoresis for discovery of SNPs显示文摘 | Tam PO Tong WC | 2001 | Biotechniques2001，30，2： | 1 |
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