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| 1 | Laparoscopic vs open approach to resection of hepatocellular carcinoma in patients with known cirrhosis:Systematic review and meta-analysis显示文摘AIM: To review the currently available literature comparing laparoscopic to open resection of hepatocellular carcinoma(HCC) in patients with known liver cirrhosis.METHODS: A literature search of MEDLINE, EMBASE, and Cochrane databases was conducted. The search terms used included(laparoscopic OR laparoscopy) AND(hepatic or liver) AND(surgery or resection) AND 'hepatocellular carcinoma' AND(cirrhosis or cirrhotic). Furthermore, to widen the search, we also used the 'related articles' section. Studies reporting a comparison of outcomes and methods of open vs laparoscopic hepatic resection for HCC in patients with liver cirrhosis were included. Meta-analysis of results was performed using a random effects model to compute relative risk(RR) and for dichotomous variablesand standard mean differences(SMD) for continuous variables.RESULTS: A total of 420 patients from 4 cohort studies were included in final analysis. Patients undergoing laparoscopic procedures had statistically less blood loss compared to the open cohort, SMD of-1.01(95%CI:-1.23-0.79), P < 0.001, with a reduced risk of transfusion, RR = 0.19(95%CI: 0.09-0.38), P < 0.001. A wider clearance at tumour resection margins was achieved following a laparoscopic approach, SMD of 0.34(95%CI: 0.08-0.60), P = 0.011. No significant difference was noted between laparoscopic and open resection operative times, SMD of-0.15(95%CI: 0.35-0.05), P = 0.142. The overall RR of suffering from postoperative morbidity is 0.25 in favour of the open surgery cohort(95%CI: 0.17-0.37), P < 0.001. Patients under-going laparoscopic surgery had significantly shorter length of stays in hospital compared to the open cohort, SMD of-0.53(95%CI:-0.73 to-0.32), P < 0.001.CONCLUSION: This review suggests that laparoscopic resection of hepatocellular carcinoma in patients with cirrhosis is safe and may provide improved patient outcomes when compared to the open technique. | Ahmed Twaij Philip H Pucher Mikael H Sodergren Tamara Gall Ara Darzi Long R Jiao | 2014 | World Journal of Gastroenterology2014，20，25： | 16 |
| 2 | Design optimization of a hydrogen ad- vanced loop heat pipe for spacebased IR sensor and detector cry cooling显示文摘 | Triem T H Tamara A O | 2003 | SPIE2003，5172，： | 1 |
| 3 | Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study显示文摘 | Ronenn Roubenoff Helen Parise Hélène A Payette Leslie W Abad Ralph D’Agostino Paul F Jacques Peter W.F Wilson Charles A Dinarello Tamara B Harris | 2003 | The American Journal of Medicine2003，，6： | 1 |
| 4 | Assess- ment of vision - related quality of life in patients with central retinal artery occlusion 显示文摘 | Martin wager MD tamara pichler MS gabriele h franke PHD | 2014 | The journal of retinal and vitreous diseases2014，34，3： | 1 |
| 5 | Terpenoids and sterols in Cladophoar vagabunda 显示文摘 | Ivaylo E Tamara G Petia H | 1995 | Phytochemistry1995，38，45： | 1 |
| 6 | Change in partnershipsand HIV risk behaviors after partner notification显示文摘 | Tamara H ancy ES homas A | 2003 | SexTransm Dis2003，30，1： | 1 |
| 7 | CognitivePharmacologic Functional Magnetic Resonance Imaing In Tourette Syndrome:A Pilot Study显示文摘 | TAMARA H KEVIN J B JOHANNA M H | 2004 | Biol Psychiatry2004，，55： | 1 |
| 8 | Social support buffers the im- pact of functional impairments on caregiver psychological well be- ing in the context of brain tumor and other cancers显示文摘 | Tamara O Laura H Suzanne KC | 2010 | Psycho Oncol2010，19，10： | 1 |
| 9 | Design optimization of a hydrogen advanced loop heat pipe for space-based IR sensor and detector cry cooling显示文摘 | TRIEM T H TAMARA A O | 2003 | SPIE2003，5172，： | 1 |
| 10 | Optimal cultural and physiological conditions for handling Streptomycs rimosus protoplasts显示文摘 | JASENKA P DASLAV H TAMARA S | 1982 | Applied and Environmental Microbiology1982，44，5： | 1 |
| 11 | Diversity of the total bacterial community associated with Ghanaian and Brazilian cocoa bean fermentation samples as revealed by a 16 S rRNA gene clone library显示文摘 | Tamara G A Zoi P Hugo H | | 0，，： | 1 |
| 12 | Social support buffers the impact of functional impairments on caregiver psychological well-being in the context of brain tumor and other cancers显示文摘 | Tamara O Laura H Suzanne KC | 2010 | Psycho-Oncol2010，19，： | 1 |
| 13 | 1/3 Harmonic and Parametric Combination Resonace of a Roller Chain显示文摘 | Sueoka A Kondou T Tamara H | 1987 | JSME Intematoinal Journal1987，30，262： | 1 |
| 14 | Role if p27kipl and cyclin dependant kinase 2 in the proliferation of non-small lung cancer显示文摘 | Kawana H Tamara J Tanaka T | 1998 | Am J Pathol1998，153，2： | 1 |
| 15 | Circulating levels of inflam- matory markers and cancer risk in the health aging and body composi- tion cohort显示文摘 | Dora II'yasova Lisa H Tamara B | 2005 | Cancer Epidemiol Biomarkers Prev2005，14，10： | 1 |
| 16 | Cognitive-- Pharmacologic Functional Magnetic Resonance Imaging In Tourette Syndrome: A Pilot Study显示文摘 | Tamara H Kevin J B Johanna MH | 2004 | Biol Psychiatry2004，，55： | 1 |
| 17 | Circulating levels of inflammatory markers and cancer risk in the health aging and body composition co- hort显示文摘 | Dore I Lisa H Tamara B | 2005 | Cancer Epidemiol Biomarkers prey2005，14，10： | 1 |
| 18 | Graph partitioning models for parallel computing显示文摘 | Bruce H Tamara G | 2000 | Parallel Computing2000，26，： | 1 |
| 19 | 显示文摘 | Kawata S Tamara S | 1999 | J Hepatol1999，30，1： | 1 |
| 20 | yclodextrins fodesorption and solubilization of 2,4,6-trinitrotoluene and its metabolites from soil显示文摘 | Tamara W Sheramata Jalal H | 2000 | Environmental Science and Technology2000，34，： | 1 |
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