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27篇 您的检索式：作者名="THRANE L"

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	题名	作者	年代	出处	被引量
1	Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source显示文摘BACKGROUND The trans-fat containing AMLN(amylin liver non-alcoholic steatohepatitis,NASH)diet has been extensively validated in C57BL/6J mice with or without the Lep^ob/Lep^ob(ob/ob)mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating hallmarks of NASH.Due to a recent ban on trans-fats as food additive,there is a marked need for developing a new diet capable of promoting a compatible level of disease in ob/ob and C57BL/6J mice.AIM To develop a biopsy-confirmed mouse model of NASH based on an obesogenic diet with trans-fat substituted by saturated fat.METHODS Male ob/ob mice were fed AMLN diet or a modified AMLN diet with trans-fat(Primex shortening)substituted by equivalent amounts of palm oil[Gubra amylin NASH,(GAN)diet]for 8,12 and 16 wk.C57BL/6J mice were fed the same diets for 28 wk.AMLN and GAN diets had similar caloric content(40%fat kcal),fructose(22%)and cholesterol(2%)level.RESULTS The GAN diet was more obesogenic compared to the AMLN diet and impaired glucose tolerance.Biopsy-confirmed steatosis,lobular inflammation,hepatocyte ballooning,fibrotic liver lesions and hepatic transcriptome changes were similar in ob/ob mice fed the GAN or AMLN diet.C57BL/6J mice developed a mild to moderate fibrotic NASH phenotype when fed the same diets.CONCLUSION Substitution of Primex with palm oil promotes a similar phenotype of biopsyconfirmed NASH in ob/ob and C57BL/6J mice,making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments.	Michelle L Boland Denise Oro Kirstine S T■lb■l Sebastian T Thrane Jens Christian Nielsen Taylor S Cohen David E Tabor Fiona Fernandes Andrey Tovchigrechko Sanne S Veidal Paul Warrener Bret R Sellman Jacob Jelsing Michael Feigh Niels Vrang James L Trevaskis Henrik H Hansen	2019	World Journal of Gastroenterology2019，25，33：	3
2	Lost in cyberspace: barriers to bridging the digital divide in e-polities 显示文摘	Shelley II M C Thrane L E Shulman S W	2006	International Journal of Intemet and Enterprise Management2006，4，3：	1
3	Analysis of optical coherence tomography systems based on the extended Huygens Fresnel principle 显示文摘	L Thrane H T Yura P E Andersen	2000	J Opt Soc Am A2000，17，3：	1
4	Investigation of the Temperature Dependence of Dielectric Relaxation in Liquid Water by THz Reflection Spectroscopy and Molecular Dynamics Simulation显示文摘	Ronne C Thrane L Astrand P O	1997	The Journal of Chemical Physics1997，107，：	1
5	THz reflection spectroscopy of liquid water 显示文摘	Thrane L Jacobsen R H Jepsen P U	1995	Chemical Physics Letters1995，240，4：	1
6	Analysis of optical coherence tomography systems based on the extended Huygens-Fresnel principle显示文摘	THRANE L YURA H T ANDERSEN P E	2000	Journal of the Optical Society of America a-Optics Image Science and Vision2000，17，3：	1
7	Analysis of optical coherence tomography systems based on tile extended H uygens-Fresnel principle显示文摘	THRANE L YURA H T ANDERSEN P E	2000	JOSA A2000，17，3：	1
8	Closed form solution for the Wigner phase space distribution function for diffuse reflection and small angle scattering in a random medium显示文摘	YURA H T THRANE L ANDERSEN P E	2000	JOSA A2000，17，12：	1
9	Extraction of optical scattering parameters and attenuation compensation in optical collerence tomography images of multilayered tissue structures显示文摘	THRANE L FROSZ M H JΦRGENSEN T M	2004	Opt Lett2004，29，14：	1
10	Enhanced optical coherence tomography imaging by multiple scan averaging 显示文摘	Sander B Larsen M Thrane L Hougaard JL Jorgensen TM	2005	Br J Ophthalmol2005，89，2：	1
11	Optical coherence tomography显示文摘	Andersen PE Thrane L Bjerring P	2003	Ugeskr Laeger2003，165，15：	1
12	Morphology and epidermal thickness of normal skin imaged by optical coherence tomography显示文摘	Mogensen M Morsy HA Thrane L	2008	Dermatology2008，217，：	1
13	Determination of optical scattering properties of highly-scattering media in optical coherence tomography images显示文摘	Levitz D Thrane L Frosz M	2004	Optics Express2004，12，：	1
14	Analysis of optical coherence tomography systems based on the extended Huygens-Fresnel principle 显示文摘	Thrane L Yura HT Andersen PE	2000	J of the Opt! Soci of Am A2000，17，：	1
15	Extraction of optical scattering parameters and attenuation compensation in optical coherence tomography images of multilayered tissue structures 显示文摘	Thrane L! Frosz MH Rgensen TM	2004	Optics letters2004，29，：	1
16	Determination of op- tical scattering properties of highly-scattering media in optical coherence tomography images 显示文摘	Levitz D Thrane L Frosz M et at	2004	Optics Express!2004，12，：	1
17	On the effect of coarse aggregate fraction and shape on the rheologi- cal properties of self-compacting concrete显示文摘	GEIKER M R BRANDL M THRANE L N	2002	Cement Con- crete and Aggregate2002，24，1：	1
18	Optical coherence tomography in clinical examination of non-pigmented skin malignancies显示文摘	Jensen LK Thrane L Andersen PE	2003	Proc SPIE2003，5140，：	1
19	Speckle reduction in optical coherence tomography images of human skin by a spatial diversity method显示文摘	J?rgensen TM Thrane L Mogensen M	2007	Proc SPIE2007，6627，66：	1
20	Analysis of optical coherence tomography systems based on the extended Huygens-Fresnel principle显示文摘	Thrane L Yura H T Andersen P E	2000	J Opt Soc Am B2000，17，3：	1

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