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| 1 | High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test显示文摘AIM:To assess the vitamin A status of patients with Crohn's disease(CD) by evaluating serum retinol levels and the relative dose response(RDR) test(liver retinol stores).METHODS:Vitamin A nutritional status was measured by serum retinol obtained by high performance liquid chromatography and the RDR test for evaluation of the hepatic stores.Body composition was performed by densitometry by dual-energy X-ray absorptiometry.Vitamin A dietary intake was assessed from a semiquantitative food frequency questionnaire.RESULTS:This study included 38 CD patients and 33 controls.Low serum retinol concentrations were detected in 29% of CD patients vs 15% in controls(P < 0.005).The RDR test was positive in 37% of CD patients vs 12% in controls,which indicated inadequate hepatic vitamin A stores(P < 0.005).Individuals with hypovitaminosis A had lower BMI and body fat compared with those without this deficiency.There was no association between vitamin A deficiency and its dietary intake,ileal location,presence of disease activity and prior bowel resections.CONCLUSION:Patients with CD have higher prevalence of vitamin A deficiency,as assessed by two independent methods. | Márcia Soares-Mota Tianny A Silva Luanda M Gomes Marco AS Pinto Laura MC Mendon?a Maria Lúcia F Farias Tiago Nunes Andrea Ramalho Cyrla Zaltman | 2015 | World Journal of Gastroenterology2015，21，5： | 4 |
| 2 | Xylanase, protease and superdosing phytase interactions in broiler performance, carcass yield and digesta transit time显示文摘The interaction of xylanase, protease and superdosing(1,500 FTU/kg) phytase in a 2×2×2 factorial arrangement was studied in broilers fed sorghum-based diets. A total of 2,800 one-day-old unsexed Ross308 chicks were housed in 56 pens with 50 birds per pen, with or without inclusion of xylanase, protease and phytase, totaling 8 treatments and 7 replicates per treatment. Body weight(BW) and feed intake(FI)were measured at 21 and 42 days of age, and mortality corrected feed conversion ratio(FCR) was calculated for each period and cumulatively. Tibia ash and carcass yield were determined in 2 birds per replicate at 21 and 42 days of age, respectively. Digesta transit time was determined at 21, 28, 35 and 42 days of age using 5 birds per replicate. Results showed that superdosing phytase increased BW and FI at42 days of age(P < 0.05) and xylanase improved FCR(P < 0.05). Xylanase and phytase also positively influenced carcass yield and breast weight, respectively. Overall, inclusion of superdosing phytase increased transit time when included in a diet containing xylanase, and no change with protease inclusion. In conclusion, the beneficial effects of xylanase, protease and superdosing phytase in broiler performance were not additive. This limitation is likely not related to the lack of efficacy of any one of the individual enzymes but to a limitation of the bird to respond additively to successive additions of enzymes. | Tiago T.dos Santos Helen V.Masey O'Neill Gemma González-Ortiz Daniel Camacho-Fernández Carlos López-Coello | 2017 | Animal Nutrition2017，，2： | 2 |
| 3 | Evaluation of biodegradable electric conductive tube-guides and mesenchymal stem cells显示文摘AIM: To study the therapeutic effect of three tubeguides with electrical conductivity associated to mesenchymal stem cells(MSCs) on neuro-muscular regeneration after neurotmesis.METHODS: Rats with 10-mm gap nerve injury were tested using polyvinyl alcohol(PVA), PVA-carbon nanotubes(CNTs) and MSCs, and PVA-polypyrrole(PPy). The regenerated nerves and tibialis anterior muscles were processed for stereological studies after 20 wk. The functional recovery was assessed serially for gait biomechanical analysis, by extensor postural thrust, sciatic functional index and static sciatic functionalindex(SSI), and by withdrawal reflex latency(WRL). In vitro studies included cytocompatibility, flow cytometry, reverse transcriptase polymerase chain reaction and karyotype analysis of the MSCs. Histopathology of lung, liver, kidneys, and regional lymph nodes ensured the biomaterials biocompatibility. RESULTS: SSI remained negative throughout and independently from treatment. Differences between treted groups in the severity of changes in WRL existed, showing a faster regeneration for PVA-CNTs-MSCs(P < 0.05). At toe-off, less acute ankle joint angles were seen for PVA-CNTs-MSCs group(P = 0.051) suggesting improved ankle muscles function during the push off phase of the gait cycle. In PVA-PPy and PVA-CNTs groups, there was a 25% and 42% increase of average fiber area and a 13% and 21% increase of the 'minimal Feret's diameter' respectively. Stereological analysis disclosed a significantly(P < 0.05) increased myelin thickness(M), ratio myelin thickness/axon diameter(M/d) and ratio axon diameter/fiber diameter(d/D; g-ratio) in PVA-CNT-MSCs group(P < 0.05). CONCLUSION: Results revealed that treatment with MSCs and PVA-CNTs tube-guides induced better nerve fiber regeneration. Functional and kinematics analysis revealed positive synergistic effects brought by MSCs and PVA-CNTs. The PVA-CNTs and PVA-PPy are promising scaffolds with electric conductive properties, bio- and cytocompatible that might prevent the secondary neurogenic muscular atrophy by improving the reestablishment of the neuro-muscular junction. | Jorge Ribeiro Tiago Pereira Ana Rita Caseiro Paulo Armada-da-Silva Isabel Pires Justina Prada Irina Amorim Sandra Amado Miguel Franca Carolina Goncalves Maria Ascensao Lopes Jose Domingos Santos Dina Morais Silva Stefano Geuna Ana Lúcia Luís Ana Colette Maurício | 2015 | World Journal of Stem Cells2015，7，6： | 2 |
| 4 | Growth and proteolytic activity of hairy roots from Centaurea calcitrapa-effect of nitrogen and sucrose显示文摘 | Pedro M L L Susana de C Tiago M M | 2002 | Enzyme and Microbial Technology2002，31，3： | 1 |
| 5 | Partial root zone drying:effects on growth and fruit quality of field-grown grapevines(Vitis vinifera)显示文摘 | Tiago P Carlos M L Rodrigues M L | 2003 | Functional Plant Biology2003，30，6： | 1 |
| 6 | Growth and proteolytic activity of hairy roots from Centaurea calcitrapa: effect of nitrogen and sucrose 显示文摘 | Pedro M L L Susana D C Tiago M M | 2002 | Enzyme Microb Technol2002，31，： | 1 |
| 7 | Granulocyte colony stimulat-ing factor induce neulrophil to secret macrophage colony-stimulat- ing factor 显示文摘 | San tiago E Mora L BautistaM | 2009 | Cytokine2009，15，： | 1 |
| 8 | Thermal characteristics analysis of an IGBT using a fiber bragg grating显示文摘 | BAZZO J P TIAGO L MARCIO V | 2012 | Optics and La- sers in Engineering2012，50，2： | 1 |
| 9 | Cerebral oedema is not responsible for motor or cognitive deficits in rats with hepatic encephalopathy显示文摘 | Omar Cauli Marta Llansola Ana Agustí Regina Rodrigo Vicente Hernández‐Rabaza Tiago B. Rodrigues Pilar López‐Larrubia Sebastián Cerdán Vicente Felipo | 2014 | Liver Int2014，，3： | 1 |
| 10 | Mediation in Local Educational Governance:the Educating Cities movement in a Portuguese town显示文摘 | JOANA L(U)CIO TIAGO NEVES | 2010 | European Educational Research Journal Volume2010，94，： | 1 |
| 11 | Lactobacillus paracasei isolated from grape sourdough:acid,bile,salt,and heat tolerance after spray drying with skim milk and cheese whey显示文摘 | EUNICE C I TIAGO S JULIANAU G L | 2015 | European Food Research Technology2015，240，： | 1 |
| 12 | Moisture relationships in composting processes显示文摘 | Tom L Richard H V M Hamelers Adrie Veeken Tiago Silva | 2002 | Compost Science & Utilization2002，10，4： | 1 |
| 13 | Thermal characteristics analysis of an IGBT using a fiber brag grating 显示文摘 | BAZZO J P TIAGO L MARCIO V | 2012 | Opt Lasers Eng2012，50，2： | 1 |
| 14 | Quasiparticle Elec- tronic Structure of Bismuth Telluride in the GW Approx- imation 显示文摘 | Kioupakis E Tiago M L Louie S G | 2010 | Phys Rev B2010，82，24： | 1 |
| 15 | Thermal characteristics analysis of an IGBT using a fiber bragg grating 显示文摘 | BAZZO J P TIAGO L MARCIO V | 2012 | Optics and Lasers in Engineering2012，50，2： | 1 |
| 16 | Surface Energetics and Growth of Pentacene 显示文摘 | Northrup J E Tiago M L Louie S G | 2002 | Phys Rev B2002，，： | 1 |
| 17 | Antibioticresistance of enterococci and related bacteria in an urban wastewater treatment plant显示文摘 | DA SILVA M F TIAGO l VER|SSIMO A | 2006 | FEMS Microbiology Ecology2006，55，2： | 1 |
| 18 | Effects of deficit irrigation strategies on cluster microclimate for improving fruit composition of Moscatel field-grown grapevines显示文摘 | Tiago P S Carlos M L Lucilia M R | 2007 | Scientia Horticulturae2007，112，3： | 1 |
| 19 | Thermal Characteristics Analysis of an IGBT Using a Fiber Bragg Grating显示文摘 | Bazzo J P Tiago L Marcio V | 2012 | Optics and Lasers in Engineering2012，50，： | 1 |
| 20 | Growth and proteolytic activity of hairy roots from Centaurea calcitrapa: effect of nitrogen and sucrose 显示文摘 | PEDRO M L LOURENCO S C TIAGO M M | 2002 | Enzyme and Microbial Technology2002，31，3： | 1 |
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