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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Effects of habitat and landscape fragmentation on humans and hiodiversity in densely populated landscapes显示文摘 | Giulio M D Holderegger R Tobias S | 2009 | Journal o( Environmental Mmagement2009，90，10： | 1 |
| 3 | Investigating the five facet mindfulness questionnaire (FFMQ):construction of a short form and evidence of a two-factor higher order structure of mindfulness显示文摘 | ULRICH S TRAN TOBIAS M GLUCK INGO W NADER | 2013 | Journal of Clinical Psychology2013，69，9： | 1 |
| 4 | Bradycardia with sevoflurane induction in patients with trisomy 21显示文摘 | Roodman S Bothwell M Tobias JD | 2003 | Paediatr Anaesth2003，13，6： | 1 |
| 5 | Harald,Experimental demonstration of free-space decoy-state quantum key distribution over 144km显示文摘 | Tobias S M Henning W Martin F | 2007 | Phys Rev Lett2007，98，01： | 1 |
| 6 | Green's function construction for 2D and 3D elastic random media显示文摘 | Tobias M M Serge A S | 1999 | Expanded Abstracts of 69^th Annual Internal SEG Mtg1999，，： | 1 |
| 7 | The Pelation between the Static and the Dynamic Cutting of Metals显示文摘 | Das M K Tobias S A | 1967 | Inter- national Journal of Machince Tools and Manufac- ture1967，7，： | 1 |
| 8 | Quality evaluation of restored soils with a fuzzy logic expert system显示文摘 | Kaufmann M Tobias S Schulin R | 2009 | Geoderma2009，151，： | 1 |
| 9 | Removing and adding edges for the traveling salesman problem显示文摘 | TOBIAS M OLA S | 2016 | Journal of the ACM2016，63，1： | 1 |
| 10 | Rep and Rep' protein of porcine circovirus type 1 bind to the origin of replication in vitro显示文摘 | TOBIAS S TIM F ANNETI'E M | 2001 | Virol2001，291，1： | 1 |
| 11 | Effects of habitat andlandscape fragmentation on humans and biodiversity in denselypopulated landscapes 显示文摘 | Giulio M D Holderegger R Tobias S | 2009 | Journal of Environmental Management2009，90，10： | 1 |
| 12 | Delayed grafting of BDNF and NT- 3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues automized red nucleus neurons from loss and atrophy, and provides limited regeneration显示文摘 | Tobias C A Shumsky J S Shibata M | 2003 | Exp Neurol2003，184，1： | 1 |
| 13 | How Nationaland International Financial Development Affect Industrial R&D显示文摘 | Keith E M Rebecca N Tobias S | 2012 | European Economic Review2012，56，1： | 1 |
| 14 | Quality evalua- tion of restored soils with a fuzzy logic expert system显示文摘 | KAUFMANN M TOBIAS S SCHULIN R | 2009 | Geoderma2009，151，： | 1 |
| 15 | Optimal driving strategy for traction energy saving on DC suburban railways 显示文摘 | Bocharnikov Y V Hillmansen S Tobias A M | 2007 | IET Electric Power Applications2007，1，5： | 1 |
| 16 | Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy,and provides limited regeneration 显示文摘 | TOBIAS C A SHUMSKY J S SHIBATA M | 2003 | Exp Neurol2003，184，1： | 1 |
| 17 | Non-fatal disease burden associated with excessbody mass index and waist circurmference in New Zealand adults 显示文摘 | Turkey M Tobias M Paul S | 2006 | Aust N ZJ Public Health2006，30，3： | 1 |
| 18 | An invitro study of the antibacterial and antifungal proper of an irreversible hydrocolloid impression material impregnated with disinfectant显示文摘 | TOBIAS R S BROWNE R M WILSON C A | 1989 | J Prosthet Dent1989，62，： | 1 |
| 19 | Oxyanions in metalliferous sediments: Tracers for paleoseawater metal concentrations显示文摘 | Tobias S Jennifer M | 2000 | Geochimica et Cosmochimica Acta2000，63，13： | 1 |
| 20 | Quality evaluation of restored soils with a fuzzy logic expert system显示文摘 | Kaufmann M Tobias S Schulin R | 2009 | Geoderma2009，151，： | 1 |
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