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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Validation and comparison of advanced differential interferometry techniques: murcia metropolitan area case study显示文摘 | HERRERA G TOMAS R LOPEZ-SANCHEZ J M DELGADO J VICENTE F MULAS J COOKSLEY G SANCHEZ M DURO J ARNAUD A BLANCO P DUQUE S MALLORQUI J J DE la VEGA-PANIZO R MONSERRAT O | 2008 | ISPRS Journal of Photogrammetry and Remote Sensing2008，，： | 1 |
| 3 | Oxidative elimination of cyanotoxins : comparison of ozone, chlorine, chlorine dioxide and permanganate显示文摘 | RODRIGUEZ EVA ONSTAD GRETCHEN D KULL TOMAS P J | 2007 | Water Research2007，41，15： | 1 |
| 4 | Synthesis of black ceramic pig- ments from secondary raw materials 显示文摘 | Costa G Della V P Ribeiro M J De Oliverira Antonio Pedro Novaes Monros Tomas Guillermo Labrineha Batista Joao Antonio | 2008 | Dyes and Pig- ments2008，，77： | 1 |
| 5 | Phosphorus Composition and Release in Sediment Bacteria of the Genus Pesudomonas During Aerobic and Anaerobic Conditions显示文摘 | Mats J Kurt P | 1993 | Hydrobiologia1993，253，： | 1 |
| 6 | Comparing Elite Soldiers' Perceptions of Psychological and Physical Demands during Miliatry Training显示文摘 | Tomas J Adler A B Wittels P | 2004 | Mili Med2004，169，7： | 1 |
| 7 | A new Legionella species, Legionella feeleii species Nova, causes Pontiac fever in an automobile plant显示文摘 | Herwaldt L A Gorman G W McGrath T Toma S Brake B Hightower A W Jones J Reingold A L Boxer P A Tang P W | 1984 | Annals of Internal Medicine1984，100，3： | 1 |
| 8 | The intestinal microbiota in the rat model:major breakthroughs from new technologies显示文摘 | Tomas J Langella P Cherbuy C | 2012 | Anim Health Res Rev2012，13，1： | 1 |
| 9 | Bronchoscopic volume reduction with valve implants in patients with severe emphysema显示文摘 | Toma T P Hopkinson N S Hillier J | 2003 | Lancet2003，361，9361： | 1 |
| 10 | Yeast the soul of beer's aroma-a review of flavour-active esters and higher alcohols produced by the brewing yeast显示文摘 | EDUARDO J P JOSE A T TOMAS B | 2014 | Appl Microbiol Biotechnol2014，98，： | 1 |
| 11 | Ins,outs,and the duration of trade显示文摘 | TIBOR B TOMAS J P | 2006 | Canadian Journal of Economics2006，39，1： | 1 |
| 12 | Visualization of ontologies to specify semantic descriptions of serv- ices显示文摘 | J J Samper V R Tomas E Carrillo Rogerio P C Do Nascimento | 2008 | IEEE Transactions on Knowledge and Data Engineering2008，20，1： | 1 |
| 13 | Product differentiation and duration of US import trade显示文摘 | TIBOR B TOMAS J P | 2006 | Journal Of International Economics2006，，70： | 1 |
| 14 | Patterns of invasion in temperate nature reserves显示文摘 | Petr P Vojtech J Tomas K | 2002 | Biological Conservation2002，104，： | 1 |
| 15 | POEMS syn- drome with severe neurological damage clinically recovered with lenalidomide显示文摘 | Tomas J F Giraldo P Lecumberri R | 2012 | Haematologica2012，97，2： | 1 |
| 16 | Bronchoscopic volume reduction with valve implants in patients with severe emphysema显示文摘 | Toma T P Hopkinson N S Hiller J | 2003 | Lancet2003，361，： | 1 |
| 17 | Horizontal and vertical structure of cross-equatorial wave propagation 显示文摘 | Tomas R A Webster P J | 1994 | Journal of the Atmospheric Sciences1994，51，： | 1 |
| 18 | Activation by retinoids of the uncoupling protein V CPl 显示文摘 | Tomas P Jimenez-Jimenez J Zaragoza P | 2004 | Biochim Biophys Acta2004，1658，12： | 1 |
| 19 | Bronchoscopic volume reduction with valve implants in patiens with severe emphysema显示文摘 | Toma T P Hopkinson N S Hillier J | 2003 | Lancet2003，361，： | 1 |
| 20 | Bronchoscopic lung volume reduction in patients with severe emphysema:anesthetic management显示文摘 | Hillier J E Toma T P Gillbe C E | 2004 | Anesth Analg2004，99，： | 1 |
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