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| 1 | Safety of immediate endoscopic sphincterotomy in acutesuppurative cholangitis caused by choledocholithiasis显示文摘AIM: To examine the safety of immediate endoscopic sphincterotomy(EST) in patients with acute suppurative cholangitis(ASC) caused by choledocholithiasis, as compared with elective EST.METHODS: Patients with ASC due to choledocholithiasis were allocated to two groups: Those who underwent EST immediately and those who underwent EBD followed by EST 1 wk later because they were under anticoagulant therapy, had a coagulopathy(international normalized ratio > 1.3, partial thromboplastin time greater than twice that of control), or had a platelet count < 50000 × 103/μL. One of four trainees [200-400 cases of endoscopic retrograde cholangiopancreatography(ERCP)] supervised by a specialist(> 10000 cases of ERCP) performed the procedures. The success and complication rates associated with EST in each group were examined.RESULTS: Of the 87 patients with ASC, 59 were in the immediate EST group and 28 in the elective EST group. EST was successful in all patients in both groups. There were no complications associated with EST in either group of patients, although white blood cell count, C-reactiveprotein, total bilirubin, and serum concentrations of liver enzymes just before EST were significantly higher in the immediate EST group than in the elective EST group.CONCLUSION: Immediate EST can be as safe as elective EST for patients with ASC associated with choledocholithiasis provided they are not under anticoagulant therapy, or do not have a coagulopathy or a platelet count < 50000 × 103/μL. Moreover, the procedure was safely performed by a trainee under the supervision of an experienced specialist. | Tomoyasu Ito Jin Kan Sai Hironao Okubo Hiroaki Saito Shigeto Ishii Ryo Kanazawa Ko Tomishima SumioWatanabe Shuichiro Shiina | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，3： | 10 |
| 2 | Development of the Immunomagnetic Enrichment Method Selective for Vibrio parahaemolyticus Serotype K and Its Application to Food Poisoning Study 显示文摘 | TAKAHIRO TOMOYASU | 1992 | Appled and environmental microbiology1992，58，8： | 1 |
| 3 | Optimal conduit size of the extracardiac Fontan operation based on energy loss and flow stagnation显示文摘 | Itatani K Miyaji K Tomoyasu T | 2009 | Ann Thorac Surg2009，88，2： | 1 |
| 4 | Enhancement by bufalin of retinoic acid-induced differentiation of acute promyelocytic leukemia cells in primary culture显示文摘 | Yamada K Hino K Tomoyasu S | 1998 | Leuk Res1998，22，7： | 1 |
| 5 | Oxidative decomposition of formaldehyde on silver-cerium composite oxide catalyst显示文摘 | Seiichiro Imamura Daisuke Uchihori Kazunori Utani Tomoyasu Ito | 1994 | Catalysis Letters (-)1994，，3： | 1 |
| 6 | Enhancement by bufalin of retinoic acid-induced differentiation of acute promyelocytic leukemia cells in primary culture显示文摘 | Hino K Tomoyasu S | 1998 | Leuk Res1998，22，7： | 1 |
| 7 | Phase relation of Sm-Fe-V alloys around the compound Sin3 (Fe, V)29 显示文摘 | Satoshi Sugimoto Tomoyasu Shimono Hajime Nakamura | 1996 | Mater Trans J M1996，37，3： | 1 |
| 8 | Intravesical instillation of Adriamycin in the presence or absence of verapamil for the treatment of superficial bladder cancer: preliminary report of a collaborative study显示文摘 | Yoshitada Ohi Hiroyuki Ohmori Tsutomu Shirahama Motoshi Kawahara Yosuke Matsumura Tomoyasu Tsushima Yasuo Ohashi | 1992 | Cancer Chemotherapy and Pharmacology1992，，1： | 1 |
| 9 | Development of the immunomagnetic en- richment method selective for vibrio parahaemolyticus serotype K and its application to food poisoning study显示文摘 | Tomoyasu T | 1992 | Appl Environ Microbiol1992，58，8： | 1 |
| 10 | Expression and purification of a small cytokine growth-blocking peptide from armyworm Pseudaletia separata by an optimized fermentation method using the methylotrophic yeast Pichia pastoris显示文摘 | Nozomi Koganesawa Tomoyasu Aizawa Hiroshi Shimojo Kazunori Miura Atsushi Ohnishi Makoto Demura Yoichi Hayakawa Katsutoshi Nitta Keiichi Kawano | 2002 | Protein Expression and Purification2002，，3： | 1 |
| 11 | Development of the immunomagnetic enrichment method selective for Vibrio parahaemoly- ticus serotype K and its application to food poisoning study显示文摘 | Tomoyasu T | 1992 | Appl Environ Microbiol1992，58，8： | 1 |
| 12 | Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soft microatganisms显示文摘 | TOMOYASU H TOSHIAKI S SATOSHI O | 2010 | Proceedings of the Japan Academy2010，86，2： | 1 |
| 13 | Band Structure of Acoustic Waves in Phononic Lattices : Two-dimensional Composites with Large Acoustic Mismatch显示文摘 | Tanaka Y Tomoyasu Y Tamura S | 2000 | Physical Review B2000，62，11： | 1 |
| 14 | Relationship between structure and antiproliferative activity of polymethoxyflavones towards HL60 cells显示文摘 | SATORU K TOMOYASU I TAKESHI H | 2012 | Anticancer Res2012，32，12： | 1 |
| 15 | Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium 显示文摘 | Tomoyasu Y Miller S C Tomita S | 2008 | Genome Biolo- gy2008，9，1： | 1 |
| 16 | Paramedian pontine infarction, neurological topographical correlation 显示文摘 | Satoshi K Ariyuki H Tomoyasu S | 1997 | Stroke1997，28，： | 1 |
| 17 | Conditioned reaction to cancer chemotherapy:percent reinforcement predicts anticipatory nausea显示文摘 | Tomoyasu N Bovbjerg DH Jacobsen PB | 1996 | Physiol Behav1996，59，2： | 1 |
| 18 | New method for evaluation of lung lymph flow rate with intact lymphatics in anaesthetized sheep 显示文摘 | Naito T Ozawa Y Tomoyasu M | 2006 | Acta Physiol (Oxf)2006，188，2： | 1 |
| 19 | Effects of disruption of heat shock genes on susceptibility of Escherichia coli to fluoroquinolones 显示文摘 | Yamaguchi Y Tomoyasu T Takaya A | 2003 | BMC Microbiol2003，3，1： | 1 |
| 20 | The heat shock response of Escherichia coli显示文摘 | Arsene f TOMOYASU T BUKAU B | 2000 | International Journal of Food Microbiology2000，55，13： | 1 |
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