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| 1 | Anatomically realistic multiscale models of normal and abnormal gastrointestinal electrical activity显示文摘One of the major aims of the International Union of Physiological Sciences (IUPS) Physiome Project is to develop multiscale mathematical and computer models that can be used to help understand human health. We present here a small facet of this broad plan that applies to the gastrointestinal system. Specifically, we present an anatomically and physiologically based modelling framework that is capable of simulating normal and pathological electrical activity within the stomach and small intestine. The continuum models used within this framework have been created using anatomical information derived from common medical imaging modalities and data from the Visible Human Project. These models explicitly incorporate the various smooth muscle layers and networks of interstitial cells of Cajal (ICC) that are known to exist within the walls of the stomach and small bowel. Electrical activity within individual ICCs and smooth muscle cells is simulated using a previously published simplified representation of the cell level electrical activity. This simulated cell level activity is incorporated into a bidomain representation of the tissue, allowing electrical activity of the entire stomach or intestine to be simulated in the anatomically derived models. This electrical modelling framework successfully replicates many of the qualitative features of the slow wave activity within the stomach and intestine and has also been used to investigate activity associated with functional uncoupling of the stomach. | Leo K Cheng Rie Komuro Travis M Austin Martin L Buist Andrew J Pullan | 2007 | World Journal of Gastroenterology2007，13，9： | 3 |
| 2 | Wavefront-optimized surface retreatments of refractive error following previous laser refractive surgery: a retrospective study显示文摘Background:Retreatments are sometimes necessary to correct residual or induced refractive errors following refractive surgery.Many different combinations of primary treatment methods and retreatment techniques have been studied,however,few studies have investigated wavefront-optimized(WFO)technology for retreatment following primary refractive surgery.This study aimed to report the outcomes of WFO photorefractive keratectomy(PRK)retreatments of refractive error following previous laser refractive surgery with PRK,laser in situ keratomileusis(LASIK),or laser-assisted subepithelial keratectomy(LASEK).Methods:We reviewed records of patients who underwent WFO PRK retreatments using the Allegretto Wave Eye-Q 400 Hz Excimer Laser System(Alcon Surgical)between January 2008 and April 2011 at Walter Reed Army Medical Center and Madigan Army Medical Center.Outcomes were recorded in terms of uncorrected distance visual acuity(UDVA),manifest refraction spherical equivalent(MRSE),corrected distance visual acuity(CDVA),and complications at 1 month(M),3 M,and 6 M post-op.Results:Seventy-eight patients(120 eyes)underwent WFO PRK retreatment during the study period.Primary surgery was surface ablation in 87 eyes(78 PRK,9 LASEK)and LASIK in 33 eyes.The mean spherical equivalent before retreatment was−0.79±0.94 D(−3.00 to 1.88 D).UDVA was≥20/20 in 69 eyes(60.0%)at 1 M,54 eyes(71.1%)at 3 M,and 27 eyes(73.0%)at 6 M follow-up.MRSE was within±0.50 D of emmetropia in 78 eyes(67.8%)at 1 M,59 eyes(77.6%)at 3 M,and 25 eyes(67.6%)at 6 M follow-up.CDVA was maintained within±1 line of pre-op in 113 of 115 eyes(98.3%)at 1 M,74 of 76 eyes(97.4%)at 3 M,and 37 eyes(100%)at 6 M follow-up.Conclusion:Although follow-up was limited beyond 3 M,WFO PRK retreatments in patients with residual refractive error may be a safe and effective procedure.Further studies are necessary to determine the long-term safety and stability of outcomes. | Kevin M.Broderick Rose K Sia Denise S.Ryan Richard D.Stutzman Michael J.Mines Travis C.Frazier Mark F.Torres Kraig S.Bower | 2016 | Eye and Vision2016，3，1： | 3 |
| 3 | Mutations in the human retinal degeneration slow gene in autosomal dominant retinitis pigmentosa显示文摘 | Hahn LB Mukai S Travis GH Berson EL Dryja TP | 1991 | Nature1991，354，6353： | 1 |
| 4 | Evolving concepts in the pathol- ogy and compated tomography imaging of lung adenocarcinoma and bron chioloaveolar carcinoma显示文摘 | Travis WD Garg K FranK | 2005 | Journal of Clinical oncolorgy2005，23，14： | 1 |
| 5 | Risk of leukemia after platinum -based chemotherapy for ovarian cancer显示文摘 | Travis LB Holowaty EJ Bergfeldt K | | 0，，： | 1 |
| 6 | Composition-structure Relationships in Simplified Nuclear Waste Glasses:Mixed Alkali Borosilicate Glasses显示文摘 | Connelly A J Travis K P Hyatt N C | 2011 | Journal of the American Ceramic Soeiety2011，94，1： | 1 |
| 7 | Kinetics of catalyzed acid/acid and acid/aldehyde condensation reactions to non-symmetric ketones显示文摘 | Travis S H Dooley K M | 2003 | Catalysis Today2003，85，234： | 1 |
| 8 | A computational fluid dynamics model of a solid oxide fuel cell显示文摘 | K Sudaprasert R P Travis R F Martinez-Botas | 2005 | ProQuest Science Jounals2005，159，： | 1 |
| 9 | on the Deep Drawing of Cups with Punch and Blank-Holding Forces Proportional to a Hydraulic Pressure显示文摘 | Thiruvarudchelvan S Travis F W Poh T K | 1999 | Journal of Materials Processing Technology1999，9293，1： | 1 |
| 10 | ACR Appropriateness Criteria? Rib Fractures显示文摘 | Travis S Jacobo K Jeffrey P | 2014 | J Thorac Imaging2014，29，6： | 1 |
| 11 | Ad- hesion of perichondrial cells to a polylactic acid scaffold 显示文摘 | ALEXANDER G TRAVIS J K ALBERT C C | 2003 | J Orthopaed Res2003，21，4： | 1 |
| 12 | Estrogen therapy and brain muscarinic receptor density in healthy females:A SPET study显示文摘 | Norbury R Travis M J Erlandsson K | 2007 | Horm Behav2007，51，2： | 1 |
| 13 | Genotype and elevation influence Spartina alterniflora colonization and growth in a created salt marsh显示文摘 | Proffitt C E Travis S E Edwards K R | | 0，，01： | 1 |
| 14 | Lymphoid pneumonitis in 50 adult patients infected with the human immunodeficiency virus: lymphocytic interstitial pneumonitis versus non-specific interstitial pneumonitis显示文摘 | Travis W D Fox C H Devaney K O | 1992 | Hum Pathol1992，23，： | 1 |
| 15 | Idiopathic Nonspicific Interstitial Pneumonia: Prognostic significance of cellular and fibrosing patterns survival comparison with Usual Interstitial Pneumonia and Desquamative Interstitial Pneumonia显示文摘 | Travis WO Matsui K Moos J | 2000 | Am J Surg Pathol2000，24，： | 1 |
| 16 | Risk of leukemia after platinum-based chemotherapy for ovarian cancer 显示文摘 | Travis LB Holowaty El Bergfeldt K | 2002 | N Engl J2002，340，5： | 1 |
| 17 | IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4 + T Cells显示文摘 | Stefan Pflanz Jackie C Timans Jeanne Cheung Rency Rosales Holger Kanzler Jonathan Gilbert Linda Hibbert Tatyana Churakova Marilyn Travis Elena Vaisberg Wendy M Blumenschein Jeanine D Mattson Janet L Wagner Wayne To Sandra Zurawski Terrill K McClanahan Dan | 2002 | Immunity2002，，6： | 1 |
| 18 | Poiseuille Flow of Lennard-Jones Fluids in Narrow Slit Pores显示文摘 | Travis K P Gubbins K E | | 0，，04： | 1 |
| 19 | Evolving concepts in the pathology and computed tomography imaging of lung adenocarcinoma and bronchioloalveolar carcinoma显示文摘 | Travis WD Garg K Franklin WA | | 0，，14： | 1 |
| 20 | Idiopathic non- specific interstitial pneumonia: prognostic significance of cellular and fibrosing patterns: survival comparison with usual interstitial pneumonia and desquamative interstitial pneumonia 显示文摘 | Travis WD Matsui K Moss J | 2000 | Am J Surg Pathol2000，24，1： | 1 |
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