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| 1 | Beta-blocker therapy in elderly patients with renal dysfunction and heart failure显示文摘OBJECTIVE To assess the role of beta-blockers(BB)in patients with chronic kidney disease(CKD)aged≥75 years.METHODS AND RESULTS From January 2008 to July 2014,we included 390 consecutive patients≥75 years of age with ejection fraction≤35%and glomerular filtration rate(GFR)≤60 m L/min per 1.73 m^2.We analyzed the relationship between treatment with BB and mortality or cardiovascular events.The mean age of our population was 82.6±4.1 years.Mean ejection fraction was 27.9%±6.5%.GFR was 60-45 m L/min per 1.73 m^2 in 50.3%of patients,45-30 m L/min per 1.73 m^2 in 37.4%,and<30 m L/min per 1.73 m^2 in 12.3%.At the conclusion of follow-up,67.4%of patients were receiving BB.The median follow-up was28.04(IR:19.41-36.67)months.During the study period,211 patients(54.1%)died and 257(65.9%)had a major cardiovascular event(death or hospitalization for heart failure).BB use was significantly associated with a reduced risk of death(HR=0.51,95%CI:0.35-0.74;P<0.001).Patients receiving BB consistently showed a reduced risk of death across the different stages of CKD:stage IIIa(GFR=30-45 m L/min per 1.73 m^2;HR=0.47,95%CI:0.26-0.86,P<0.0001),stage IIIb(GFR 30-45 m L/min per 1.73 m^2;HR=0.55,95%CI:0.26-1.06,P=0.007),and stages IV and V(GFR<30 m L/min per 1.73 m~2;HR=0.29,95%CI:0.11-0.76;P=0.047).CONCLUSIONS The use of BB in elderly patients with HFr EF and renal impairment was associated with a better prognosis.Use of BB should be encouraged when possible. | Juan Martínez-Milla Marcelino Cortés García Julia Anna Palfy Mikel Taibo Urquía Marta López Castillo Ana Devesa Arbiol Ana Lucía Rivero Monteagudo María Luisa Martín Mariscal Inés Jiménez-Varas Sem Briongos Figuero Juan Antonio Franco-Pelaéz JoséTuñón | 2021 | Journal of Geriatric Cardiology2021，18，1： | 3 |
| 2 | Research on Service Life Prediction Model of Concrete Structure of Sea-crossing Bridge显示文摘According to the chloride corrosion environment,service life prediction model of concrete structure of sea-crossing bridge was built using modified Fick's second law and the whole probability calculation method,which was suitable for China. Furthermore,a visual service life prediction program of concrete structure was developed by optimized Monte Carlo method. Meanwhile,Life 365 program was compared,indicating reliability of the prediction program. Finally,the validity of prediction model was verified in JinTang Bridge of Zhoushan Island Mainland Linkage Project. | WANG C J ZHANG G Z LIU K X TU L Q LI J H QIN M Q | 2010 | 武汉理工大学学报2010，32，17： | 2 |
| 3 | Distribution Characteristics of Vehicle Specific Power on Urban Restricted Access Roadways 显示文摘 | Song G L Yu Z Tu | 2012 | Journal of Transportation Engineering (S0733-947X) ASCE2012，138，： | 1 |
| 4 | Th e I m p act s of En e rgy Pric e son En ergy I nte n sity:Evid e n ce fro m Chin a显示文摘 | HAN G L M TU M Z | 2007 | En ergyPolicy2007，35，5： | 1 |
| 5 | In vitro induction of differentia- tion by ginsenoside in SMMC-7721 hepatocarcinoma cell line显示文摘 | ZENG X L TU Z G | 2003 | Pharmacol Toxico2003，93，： | 1 |
| 6 | Microstructure,chemical and tribological investigations of MoxW1-xSy co-sputtered composite films显示文摘 | YIN G L HUANG P H YU Z HE D N TU J P | 2006 | Tribology Letters2006，22，1： | 1 |
| 7 | Cathode polarization in trivalent chromium plating 显示文摘 | Tu Z M Yang Z L | 1993 | Plating and Surface Finishing1993，80，9： | 1 |
| 8 | Phenotypic and functional character- ization of human γδT-Cell subsets in response to in fluenza a viruses显示文摘 | Qin G Liu Y Zheng J Xiang Z Ng I H Peiris J M Lau Y L Tu W | 2012 | J Infect Dis2012，205，11： | 1 |
| 9 | Reduced switching-frequency modulation and circulating current suppression for modular multilevel converters显示文摘 | TU Q R XU Z XU L | 2011 | IEEE Transactions on Power Delivery2011，26，3： | 1 |
| 10 | Reduced switching-frequency modulation and circulating current suppression for modular multilevel converter显示文摘 | Tu Q Xu Z Xu L | 2011 | IEEE Transactions on Power Delivery2011，26，3： | 1 |
| 11 | Electrochemical properties of Si/LiTi2O4 nanocomposite as anode materials for Li-ion secondary batteries显示文摘 | ZENG Z Y TU J P WANG X L ZHAO X B | 2008 | J Electroanal Chem2008，616，： | 1 |
| 12 | Cathode polarization in trivalent chromium plating 显示文摘 | Tu Z M Yang Z L | 1993 | Plating and Surface Finishing1993，79，9： | 1 |
| 13 | Photoscattering effect in supercontinuum - generating photonic crystal fiber显示文摘 | TU H MARKS D L JIANG Z | 2008 | Appl Phys Lett2008，92，06： | 1 |
| 14 | Novel c-di-GMPrecognition modes of the mouse innate immune adaptor protein STING 显示文摘 | CHIN K H TU Z L SU Y C | 2013 | Acta Crystallogr D Biol Crystallogr2013，69，3： | 1 |
| 15 | Pulse plating with a trivalent chromium plating bath显示文摘 | Tu Z M Yang Z L Zhang J S | 1990 | Plating and Surface Finishing1990，77，10： | 1 |
| 16 | Cathode Polarization in Trivalent Chromium Plating显示文摘 | Tu Z M Yang Z L | 1993 | Plating and Surface Finishing1993，79，9： | 1 |
| 17 | Photooxidation of olefins under oxygen in platinum(II) complex-loaded mesoporous mole- cular sieves 显示文摘 | Feng K Zhang R Y Wu L Z Tu B Peng M L Zhang L P Zhao D Y Tung C H | 2006 | Journal of the American Chemical Society2006，128，14： | 1 |
| 18 | Hyperbranched phosphorescent conjugated polyelectrolytes for time-resolved heparin sensing显示文摘 | Shi H F Chen X J Liu S J Xu H An Z F Lang O Y Tu Z Z Zhao Q Fan Q L Wang L H Huang W | 2013 | ACS Applied Materials Interfaces2013，5，11： | 1 |
| 19 | Reduced switching-frequency modulation and circulating current suppression for modular multilevel converters显示文摘 | TU Q XU Z XU L | 2011 | IEEE Transactions on Power Delivery2011，26，3： | 1 |
| 20 | Reduced switching-frequency modulation andcirculating current suppression for modular multilevel converter显示文摘 | Tu Q Xu Z Xu L | 2011 | IEEE Trans on Power Delivery2011，26，3： | 1 |
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