4篇
您的检索式：作者名="Tadayuki Shimada"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Estimating method of cable tension from natural frequency of high mode 显示文摘 | Shimada Tadayuki | 1994 | Proceedings of the Japan Society of Civil Engineers1994，501，29： | 1 |
| 2 | The efficiency of helical strakes for the suppression of vortex-excited oscillation of steel stacks显示文摘 | Hatsuo Ishizaki Hiroshi Hara Tadayuki Shimada | | 0，，04： | 1 |
| 3 | Neuritin: A therapeutic candidate for promoting axonal regeneration显示文摘Following injury, the axons of the mammalian central nervous system do not regenerate. Many studies have aimed at understanding the mechanisms that prevent axonal regeneration and at designing ways to overcome the obstacles preventing axonal regrowth. These studies have identified numerous proteins as promoters of axonal regeneration. In this minireviews, we focus on neuritin as a therapeutic candidate for promoting axonal regeneration. Neuritin was first identified as a neuronal-activity-inducible gene product in the rat brain. The overexpression of neuritin in neurons or the application of neuritin to neurons induces neuritogenesis, neurite arborization, and axonal elongation both in vitro and in vivo. These morphological changes are often observed during the first step of axonal regeneration. Indeed, neuritin expression increases during axonal regeneration in the peripheral nervous system(PNS). Conversely, in a mouse model of diabetes mellitus, neuritin expression decreases in the PNS, and this reduced expression may result in deficient axonal regeneration. Neuritin is induced in the hippocampal dentate gyrus after temporal lobe epilepsy or brain ischemia; however, in these conditions, neuritin induc-tion may exacerbate brain dysfunction through mossy fiber sprouting. Together, these findings support the hypothesis that tightly controlled regulation of neuritin may be required for the treatment of each unique axonal pathology. | Tadayuki Shimada Hiroko Sugiura Kanato Yamagata | 2013 | World Journal of Neurology2013，3，4： | 1 |
| 4 | Extended serotyping scheme forVibrio cholerae显示文摘 | Dr. Toshio Shimada Eiji Arakawa Kenichiro Itoh Tadayuki Okitsu Akiyoshi Matsushima Yoshio Asai Shiro Yamai Tamotsu Nakazato G. Balakrish Nair M. John Albert Yoshifumi Takeda | 1994 | Current Microbiology1994，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员