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21篇 您的检索式:作者名="TaiMA"
    题名 作者 年代 出处 被引量
1Activity and bioavailability of tepotinib for leptomeningeal metastasis of NSCLC with MET exon 14 skipping mutation显示文摘Tepotinib is a key drug for cancer patients with mesenchymal-epithelial transition receptor tyrosine kinase proto-oncogene(MET)exon 14 skipping mutation.However,its bioavailability in the cerebrospinal fluid(CSF)in humans has not been fully elucidated.Moreover,information about the efficacy of tepotinib in patients with leptomeningeal metastasis is limited.Here,we present the case of a 56-year-old man who was diagnosed with lung adenocarcinoma with MET exon 14 skipping mutation.He was urgently hospitalized due to leptomeningeal metastasis.We administered tepotinib 500 mg/day as the second-line therapy and observed improvement in leptomeningeal metastasis and performance status.The tepotinib concentrations reached 1,648 ng/mL in the plasma and 30.6 ng/mL in the CSF,with a penetration rate(CSF/plasma)of 1.83%.These demonstrate tepotinib could achieve a high rate of central nervous system transition and could be effective against leptomeningeal metastasis.Hisashi Tanaka Kageaki Taima Tomonori Makiguchi Junichi Nakagawa Takenori Niioka Sadatomo Tasaka 2021Cancer Communications2021,41,1:4
2Production of poly- β-hydroxyalkanoates) by bacterium of the genus Alkaligenes utilizing long - chain fatty acids 显示文摘Akiyama M Taima Y Doi Y 1992Applied Microbiology & Biotechnology1992,37,:1
3Effect of double-stranded RNA on the expression of epithelial neutrophil activating peptide-78/CXCL-5 in human endothelial cells显示文摘IMAIZUMI T HATAKEYAMA M TAIMA K 2004In- flammation2004,28,4:1
4Salivary gland tumors : diag- nostic value of gadolinium-enhanced dynamic MR imaging with histopathologic correlation 显示文摘Yabuunhi H Fukuya T Taima T 2003Radiology2003,226,:1
5Inhibitory effect of mandarin juice rich in b-eryptoxanthin and hesperidin on 4- (methylnitrosamino)-1- (3-pyridyl)-1-butanoneinduced pulmonary tumorigenesis in mice 显示文摘Kohno E Taima M Sumida T 2001Cancer Letters2001,174,:1
6Efficient oligothiophene: fullerene bulk heterojunction organic photovoltaic cells显示文摘SakaiJ Taima T Saito K 2008Organic Electronics2008,9,:1
7Annealing effect in the sexithiophene:C70 small molecule bulk heterojunction organic photovoltaic cells显示文摘Sakai J Taima T Yamanari T 2009Solar Energy Materials & Solar Cells2009,93,:1
8查看详情显示文摘Miyamaru F Kuboda S Taima K Takano K Hangyo M Takeda M W 0,,:1
9Investigation of optimum conditions for high-efficiency organic thin-film solar cells based on polymer blends 显示文摘YAMANARI T TAIMA T 2006Journal of Photochemistry and Photobiology A: Chemistry2006,182,:1
10Salivary gland tumors: diagnostic value d gadolinium-enhanced dynamic MR imaging with hlstopathologic correlation显示文摘Yabuunhi H Fukuya T Taima T 2003Radiology2003,226,2:1
11Treatment of postoperative pain in oral and maxillofacial surgery显示文摘Coulthard P Haywood D TaiMA 2000Br J OralMaxillofac surgery2000,38,:1
12Characterization of terahertz metamaterials fabricated on flexible plastic films: Toward fabrication of bulk metamaterials in terahertz region 显示文摘MIYAMARU F TAKEDA M W TAIMA K 2009Applied Physics Express2009,,04:1
13Efficient oligot- hiophene:Fullerene bulk heterojunction organic photovoltaic cells显示文摘Jun Sakai Tetsuya Taima Kazuhiro Saito 2009Org Electron2009,9,5:1
14New television with 2D/3D image conversion technologies显示文摘T Okino H Murata K Taima T Iinuma 0,,04:1
15Origin of the open-circuit voltage of organic thin-film solar cells based on conjugated polymers 显示文摘YAMANARI T TAIMA T SAKAI J 2009Sol Energy Mater Sol Cells2009,93,67:1
16Annealing effect in the sexithiophene:C 70 small molecule bulk heterojunction organic photovoltaic cells显示文摘Jun Sakai Tetsuya Taima Toshihiro Yamanari Kazuhiro Saito 2009Solar Energy Materials and Solar Cells2009,,6:1
17Efficient oligothiophene:fullerene bulk heterojunction organic photovoltaic cells显示文摘Jun Sakai Tetsuya Taima Kazuhiro Saito 2008Organic Electronics2008,,5:1
18Annealing effect in the sexithiophene:C 70 small molecule bulk heterojunction organic photovoltaic cells显示文摘Jun Sakai Tetsuya Taima Toshihiro Yamanari Kazuhiro Saito 2009Solar Energy Materials and Solar Cells2009,,:1
19Cardiac gap junctions: good or bad显示文摘Taima G 2000Cardiovascular Research2000,48,:1
20Chromosome-specific segmentation revealed by structural analysis of individually isolated chromosomes显示文摘Kitada K Taima A Ogasawara K 2011Genes Chromosomes Cancer2011,50,4:1
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