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| 1 | The complete mitochondrial genomes sequences of Asio flammeus and Asio otus and comparative analysis显示文摘The complete mitochondrial genomes of Asio flammeus and Asio otus were se- quenced and found to span 18858 bp and 18493 bp, respectively. It is surprising to find the for- mer to be the largest among all avian mitochondrial genomes sequenced so far. The two ge- nomes have very similar gene order with that of Gallus gallus, neither contains the pseudo con- trol region, but both have a single extra base, namely Cytidine, at position 174 in ND3 gene. The control regions of Asio flammeus and Asio otus’ mitochondrial genomes span 3288 bp and 2926 bp respectively, which are the longest among vertebrates except for Myxine glutinosa and con- tribute to the large size of two genomes. The 3′end of the control region of Asio flammeus and Asio otus contains many tandemly repeated sequences, which are highly similar to a putative control element, i.e. Mt5, and may form stable stem-loop secondary structures. Such repeated sequences probably play an important role in regulating transcription and replication of mito- chondrial genome. Our results may provide important clues for uncovering the origin and evolu- tion mechanisms of mitochondrion genome. | SUN Yi1, MA Fei1, XIAO Bing1, ZHENG Junjie2, YUAN Xiaodong2, TANG Minqian2, WANG Li3, YU Yefei3 & Li Qingwei1 1. College of Life Sciences, Liaoning Normal University, Dalian 116029, China 2. TaKaRa Biotechnology (Dalian) Co., Ltd., Dalian 116600, China 3. The Administrative Office of the Natural Protective Zone of Snake Island-Lao Tie Hill, Dalian 116041, China Correspondence should be addressed to Li Qingwei | 2004 | Science China(Life Sciences)2004，47，6： | 6 |
| 2 | Derivatization in Liquid Chromatography/Mass Spectrometric Analysis of Neurosteroids显示文摘Liquid chromatography/mass spectrometry (LC/MS) is now considered to be the most promising analytical method for the determination of biological substances, especially nonvolatile or highly polar substances However, some compounds do not show enough sensitivity in LC/MS and soft ionization methods commonly used in LC/MS, such as electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI), sometimes do not give satisfactory structural information This report presents an overview of the derivatization methods in the LC/MS analysis of neurosteroids or neuroactive neurosteroids, which are synthesized and accumulated in the nervous system The derivatization of pregnenolone 3 sulfate, one of these steroids, with 4 ( N,N dimethylaminosulfonyl) 7 hydrazino 2,1,3 benzoxadiazole gave a satisfactory sensitivity during the quantitative analysis using LC/ESI MS The obtained results are much lower than those previously obtained using gas chromatography/mass spectrometry or radioimmunoassay On the other hand, the derivatization to acetate was useful for the treatment of labile catechol estrogens in rat brains and gave enough structural information in LC/APCI MS, which confirmed the existence of catechol estrogens in mammalian | Kuniko MITAMURA, Kazutake SHIMADA (Faculty of Pharmaceutical Sciences, Kanazawa University 13 1, Takara machi, Kanazawa 920 0934, Japan) | 2001 | 色谱2001，19，6： | 5 |
| 3 | The 4th World Landslide Forum: Landslide Research and Risk Reduction for Advancing the Culture of Living with Natural Hazards显示文摘The World Landslide Forum is a triennial mainstream conference that gathers together the scientific and technological community, policymakers, industry actors, public officials, and other stakeholders, who deal with the understanding and management of landslide disaster risk. The establishment of the ISDR-ICL Sendai Partnerships 2015–2025 for Global Promotion of Understanding and Reducing Landslide Disaster Risk in Sendai during the 2015 World Conference on Disaster Risk Reduction(WCDRR) enabled the landslide science and technology community support the implementation of the Sendai Framework for Disaster Risk Reduction 2015–2030 in order to prevent new and reduce existing disaster risk.The 4th World Landslide Forum(WLF4) was held in Ljubljana, Slovenia, from 29 May to 2 June 2017 and discussed the progress of landslide research and risk reduction for advancing the culture of living with natural hazards. A high-level panel composed of United Nations officials, international stakeholders, and national organizations sought to identify the best mechanisms to be developed by the community of the International Consortium on Landslides(ICL). The objective was to advance the implementation of the ISDR-ICL Sendai Partnerships,to achieve a better commitment among partners, and to provide substantive services to developing countries. During the WLF4, the 2017 Ljubljana Declaration on Landslide Risk Reduction was adopted and the concept framework of the Kyoto 2020 Commitment was endorsed. | Irasema Alcntara-Ayala Kyoji Sassa Matjaz Miko Quinli Han Jakob Rhyner Kaoru Takara Satoru Nishikawa Badaoui Rouhban Slvano Briceo | 2017 | International Journal of Disaster Risk Science2017，8，4： | 3 |
| 4 | 发展中国家的可再生能源:沼气的机遇和挑战显示文摘能源对于现代社会至关重要,是社会经济发展最重要的指标之一。尽管科技不断发展,但仍然有约30亿人(主要集中在发展中国家的农村地区),继续通过在传统的炉灶中燃烧生物质资源(如柴薪、秸秆、动物粪便)的方式来满足烹饪的能源需求。这种方式对环境、社会、经济、公众健康都带来极大负面影响。这些地区要实现可持续性发展,开发干净清洁、价格低廉的可再生能源就势在必行。把现有的生物质资源(动物粪便、秸秆、餐厨垃圾、绿色废弃物)提炼成更加清洁高效的能源载体(例如厌氧发酵产生的沼气),不仅具有提供清洁、可靠能源的独特潜力,同时又能保护当地和全球的环境。尽管沼气对发展中国家来说意义重大,但其面临着成本高、设备安装和维护专业知识缺乏等问题,因而在地理位置分散的社区难以广泛推广应用。因此,政府和非政府层面的通力协作就显得至关重要,从而促进沼气技术的更新改造和传播,开发尚未被开发的潜力。文章旨在通过分析沼气技术的现状、挑战和潜力,明确它在发展中国家未来的研究方向和发展传播路径。 | K C Surendra Devin Takara rew G Hashimoto Samir Kumar Khanal 李谦 | 2015 | 中国沼气2015，33，1： | 3 |
| 5 | On - line preconcentration/determination of copper in parenteral solutions using activated carbon by inductively coupled plasma optical emission spectrometry 显示文摘 | TAKARA E A PASINI - CABELLO S D CERUTTI S | 2005 | J Pharmaceut Biomed2005，39，34： | 1 |
| 6 | Effects of 19 herbal extracts on the sensitivity to paclitaxel or 5-fluorouracil in HeLa cells显示文摘 | TAKARA K HORIBE S OBATA Y | 2005 | Biol Pharm Bull2005，28，1： | 1 |
| 7 | An update on over- coming MDR - 1 mediated muhidrug resistance in cancer chemo- therapy 显示文摘 | TAKARA K SAKAEDA T OKUMURA K | 2006 | Curr Pharm Des2006，12，2： | 1 |
| 8 | Umami taste enhancement of MSG/NaC1 mixtures by subthreshold L-a-aromatic amino acids显示文摘 | LIOE H N APRIYANTONO A TAKARA K | 2005 | Journal of Food Science2005，70，7： | 1 |
| 9 | Percutaneous intratumoral injection of ethanol under ultrasound imaging for treatment of small hepatocelhlar carcinoma显示文摘 | Sigura N Takara K Ohto M | 1983 | Acta Hepatol Jpn1983，24，3： | 1 |
| 10 | Low molecular weight compounds responsible for savory taste of Indonesian soy sauce显示文摘 | LIOE H N APRIYANTONO A TAKARA K | 2004 | Journal of Agricultural and Food Chemistry2004，52，19： | 1 |
| 11 | Green processing of tropical banagrass into biofuel and biobased products: an innovative biorefinery approach显示文摘 | Takara D Khanal S K | 2011 | Bioresour Technology2011，102，2： | 1 |
| 12 | Collaborative non-self rec- ognition system in S-RNase-based self-incompatibility显示文摘 | KUBO K ENTANI T TAKARA A | 2010 | Science2010，330，6005： | 1 |
| 13 | Cytotoxic T lymphocyte antigen 4 gene polymorphisms and human T cell lymphotrophie virusl infection: their associations with Hashimoto's thyroiditis in Japanese patients 显示文摘 | Tomoyose T Komiya I Takara M | 2002 | Thyroid2002，12，8： | 1 |
| 14 | 120 Gbit/s OTDM system prototype 显示文摘 | Kawanishi S Miyamoto Y Takara H | 1998 | Optical Communication1998，24，3： | 1 |
| 15 | One- hour-ahead load forecasting using neural network显示文摘 | SENJYU T TAKARA H UEZATO K | 2002 | IEEE Transactions on Power Systems2002，17，1： | 1 |
| 16 | Lys ( 173 ) Arg and -344T/C variants of CYP11 B2 in Japanese patients with low-renin hypertension 显示文摘 | Komiya I Yamada T Takara M | 2000 | Hypertension2000，35，3： | 1 |
| 17 | An update onoverco2mingMDR1-mediated multidrug resistance in cancerchemo-therapy显示文摘 | K Takara T Sakaeda K Okumura | 2006 | Curr Pharm Des2006，12，3： | 1 |
| 18 | One-hour-ahead load forecasting using neural network显示文摘 | Senjyu T Takara H Funabashi T | 2002 | IEEE Trans on Power Systems2002，17，1： | 1 |
| 19 | Association of CTLA-4 gene A/G polymorphism in Japanese type 1 diabetic patients with younger age of onset and autoimmune thyroid disese显示文摘 | Takara M Yamashiro S Komiya I | | 0，，： | 1 |
| 20 | One-hour-ahead Load Forecasting Using Neural Network显示文摘 | Senjyu T Takara H Funabashi T | 2002 | IEEE Trans on Power Systems2002，17，1： | 1 |
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