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| 1 | Peripheral portal vein-oriented non-dilated bile duct puncture for percutaneous transhepatic biliary drainage显示文摘AIM: To evaluate the efficacy of peripheral portal vein(PV)-oriented non-dilated bile duct(BD) puncture for percutaneous transhepatic biliary drainage(PTBD).METHODS: Thirty-five patients with non-dilated BDs underwent PTBD for the management of various biliary disorders, including benign bilioenteric anastomotic stricture(n = 24), BD stricture(n = 5) associated with iatrogenic BD injury, and postoperative biliary leakage(n = 6). Under ultrasonographic guidance, percutaneous transhepatic puncture using a 21-G needle was performed along the running course of the peripheral targeted non-dilated BD(preferably B6 for right-sided approach, and B3 for left-sided approach) or along the accompanying PV when the BD was not well visualized. This technique could provide an appropriate insertion angle of less than 30° between the puncture needle and BD running course. The puncture needle was then advanced slightly beyond the accompanying PV. The needle tip was moved slightly backward while injecting a small amount of contrast agent to obtain the BD image, followed by insertion of a 0.018-inch guide wire(GW). A drainage catheter was then placed usinga two-step GW method. RESULTS: PTBD was successful in 33(94.3%) of the 35 patients with non-dilated intrahepatic BDs. A rightsided approach was performed in 25 cases, while a left-sided approach was performed in 10 cases. In 31 patients, the first PTBD attempt proved successful. Four cases required a second attempt a few days later to place a drainage catheter. PTBD was successful in two cases, but the second attempt also failed in the other two cases, probably due to poor breath-holding ability. Although most patients(n = 26) had been experiencing cholangitis with fever(including septic condition in 8 cases) before PTBD, only 5(14.3%) patients encountered PTBD procedure-related complications, such as transient hemobilia and cholangitis. No major complications such as bilioarterial fistula or portal thrombosis were observed. There was no mortality in our series.CONCLUSION: Peripheral PV-oriented BD puncture for PTBD in patients with non-dilated BDs is a safe and effective procedure for BD stricture and postoperative bile leakage. | Hiroaki Shimizu Atsushi Kato Tsukasa Takayashiki Satoshi Kuboki Masayuki Ohtsuka Hideyuki Yoshitomi Katsunori Furukawa Masaru Miyazaki | 2015 | World Journal of Gastroenterology2015，21，44： | 10 |
| 2 | Clinicopathological features and prognosis of surgical resected cases of biliary cancer with pancreaticobiliary maljunction显示文摘To the Editor:Pancreaticobiliary maljunction(PBM)is a congenital anomaly in which the pancreatic and bile ducts join anatomically outside of the duodenal wall away from the Oddi’s sphincter.This condition causes the reflux of pancreatic juice into the bile duct under high pressure,resulting in various pathologic changes.The features of PBM patients are common bile duct dilatation,long common channel,and high amylase levels in bile juice.Among them,one of the most significant problems is the development of biliary cancer,including extrahepatic bile duct and gallbladder cancers[1].A nationwide survey in Japan reported biliary cancer in 21.6%of adult patients with PBM concomitant with congenital biliary dilatation,32.1%and 62.3%extrahepatic bile duct and gallbladder cancers,respectively[2]. | Tsukasa Takayashiki Hideyuki Yoshitomi Katsunori Furukawa Satoshi Kuboki Masaru Miyazaki Masayuki Ohtsuka | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，1： | 3 |
| 3 | Surgical Resection after Downsizing Chemotherapy for Initially Unresectable Locally Advanced Biliary Tract Cancer: A Retrospective Single-center Study显示文摘 | Atsushi Kato Hiroaki Shimizu Masayuki Ohtsuka Hiroyuki Yoshidome Hideyuki Yoshitomi Katsunori Furukawa Dan Takeuchi Tsukasa Takayashiki Fumio Kimura Masaru Miyazaki | 2013 | Annals of Surgical Oncology2013，，1： | 1 |
| 4 | Neuroendocrine tis- sue-specific transcription factor, BETA2/NeuroD, in gastric carci- nomas:a comparison with ehromogranin A and synaptophysin ex- pressions 显示文摘 | Fujii AL Kamiakito T Takayashiki N | 2003 | Pathol Res Pract2003，199，8： | 1 |
| 5 | Fibroblast growth factor 8 expression in breast carcinoma:associations with androgen receptor and prostate-specific antigen expressions显示文摘 | Tanaka A Kamiakito T Takayashiki N | | 0，，04： | 1 |
| 6 | Surgical strategy for mucin-producing bile duct tumor显示文摘 | Masayuki Ohtsuka Fumio Kimura Hiroaki Shimizu Hiroyuki Yoshidome Atsushi Kato Hideyuki Yoshitomi Katsunori Furukawa Noboru Mitsuhashi Dan Takeuchi Tsukasa Takayashiki Kosuke Suda Masaru Miyazaki | 2010 | Journal of Hepato - Biliary - Pancreatic Sciences2010，，3： | 1 |
| 7 | Double cancer of gallbladder and bile duct associated with anomalous junction of the pancreaticobiliary ductal system显示文摘 | Takayashiki T Miyazaki M Kato A | 2002 | Hepato-Gastroenterology2002，49，43： | 1 |
| 8 | Vitamin D3 suppresses the androgen-stimulated growth of mouse mammary carcinoma SC-3 cells by transcriptional repression of fibroblast growth factor 8 显示文摘 | Kawata H Kamiakito T Takayashiki N | 2006 | J Cell Physiol2006，207，3： | 1 |
| 9 | Infectious tolerance develops after intrathymic alloantigen-induced acceptance of rat heart allografts can be adoptively transferred 显示文摘 | Takayashiki T Asakura H Ku G | 2005 | Surgery2005，138，： | 1 |
| 10 | Double cancer of gall bladder and bile duet associated with anomalous junction of the pancreaticobiliary ductal system显示文摘 | Takayashiki T Miyazaki M Kato A | 2002 | Hepatogastroenlerology2002，49，43： | 1 |
| 11 | Neuroendocrine tissue-specific transcription factor,BETA2/NeuroD,in gastric carcinomas:a comparison with chromograninA and synaptophysin expressions显示文摘 | Fujii A Kamiakito T Takayashiki N | 2003 | Pathol Res Pract2003，199，8： | 1 |
| 12 | Recurrent pulmonary synovial sarcoma effectively treated with amrubicin:A case report 显示文摘 | Satoh H Takayashiki N Shiozawa T | 2015 | Exp Ther Med2015，9，5： | 1 |
| 13 | Increased expression of toll-like receptor 4 enhances endotoxln-induced hepatic failure in partially hepatectomized mice显示文摘 | TAKAYASHIKI T YOSHIDOME H KIMURA F | 2004 | J Hepatol2004，41，4： | 1 |
| 14 | Increased expression of toll-like receptor 4 enhances endotoxin-induced hepatic failure in partially hepateetomized mice显示文摘 | Takayashiki T Yoshidome H Kimura F | 2004 | J Hepatol2004，41，4： | 1 |
| 15 | Vitamin D3 suppresses the androgen-stimulated growth of mouse mammary carcinoma SC-3 cells by transcriptional repression of fibroblast growth factor 8显示文摘 | Kawata H Kamiakito T Takayashiki N | 2006 | Cell Physiol2006，207，3： | 1 |
| 16 | Increased expression of toll-like receptor 4 enhances endotoxin-induced hepatic failure in partially hepatectomized mice显示文摘 | Takayashiki T Yoshidome H Kimura F | 2004 | Journal of Hepatology2004，41，4： | 1 |
| 17 | Neuroendocrine tissue-specific transcription factor, BETA2/NeuroD,in gastric carcinomas: a comparison with chromogranin A and synnaptophysin expressions 显示文摘 | Fujii A Kamiakito T Takayashiki N | 2003 | Pathol Res Pract2003，199，8： | 1 |
| 18 | Increased expression of toll-like receptor 4 enhances endotoxin-induced hepatic failure in partially hepatectomized mice 显示文摘 | Takayashiki T Yoshidome H Kimura F | 2004 | J Hepatol2004，41，： | 1 |
| 19 | Neuroendocrine tissue-specific transcription factor, BETA2/NeuroD, in gastric carcinomas: a comparison with chromogranin A and synaptophysin expressions 显示文摘 | Fujii A Kamiakito T Takayashiki N | 2003 | Pathol Res Pratt2003，199，8： | 1 |
| 20 | Similarities and Differences Between Intraductal Papillary Tumors of the Bile Duct With and Without Macroscopically Visible Mucin Secretion显示文摘 | Masayuki Ohtsuka Fumio Kimura Hiroaki Shimizu Hiroyuki Yoshidome Atsushi Kato Hideyuki Yoshitomi Katsunori Furukawa Dan Takeuchi Tsukasa Takayashiki Kosuke Suda Shigetsugu Takano Yoichiro Kondo Masaru Miyazaki | 2011 | The American Journal of Surgical Pathology2011，，4： | 1 |
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