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| 1 | Effect of preoperative regional artery chemotherapy on proliferation and apoptosis of gastric carcinoma cells显示文摘AIM: To study the effects of preoperative regional arterychemotherapy (PRACT) in inducing growth inhibition andapoptosis of gastric carcinorna (GC) calls.METHODS: TUNEL ( terminal-deoxynucleotidyl-transferaseTdT-mediated dUTP-fluorescein and labeling) method andimmunohistochemical techniques were used to detect thestate of apoptosis and proliferation of GC cells inhistopathologic sections. A total of 110 cases of GC and 68cases of metastatic lymph node with or without PRACT wereadopted. Correlations between apoptosis index (Al),proliferation index (PI) and PRACT and prognosis wereanalysed.RESULTS: The apoptosis index (Al) was significantly higherin the PRACT group (12.5 ‰ + 4.33‰) than in the untreatedgroup (7. 1‰ + 3. 43 ‰, P < 0. 001 ), whereas theproliferation index (PI) in the PRACT group (33.8 % ± 8.8% ) was eignificantly lower than that in untreated group (43.6 % + 12.8 %, P<0.01). Both Al and PI were correlated tothe differentiation degree of GC in PRACT group, the Al inthe differentiated group was higher than that inundifferentiated group (P<0.001), but the PI was lower inthe differentiated group than that of the undifferentiatedgroup ( P < 0.01 ). The Al of GC cells in metastatic lymphnode was also significantly higher in the PRACT group (7.9‰+ 3.41‰) than in the untreated group (3.6 ‰ + 2.93 ‰,P < 0.01 ), though the PI of GC cells in metastatic lymphnodes in the PRACT group (17. 2 % + 6. 8 % ) wassignificantly lower than that in the untreated group (26.7 %+ 9. 3 %, P < 0. 01 ). The severity of histopathologicchanges was significantly higher in the PRACT group than inthe untreated group ( P < 0.05). In addition, postoperativesurveys demonstrated that the 5-year survival rate of GCpatients in the PRACT group was significantly higher than thatof patients in the untreated group (P<0.01).CONCLUSION: Preoperative regional artery chemotherapy(PRACT) showed inhibitory action on the growth of GC cellsmainly through inhibiting proliferation and inducing theapoptosis of tumor cells. PRACT can improve the prognosisof GC patients also. | Tao, HQ Zou, SC | 2002 | World Journal of Gastroenterology2002，8，3： | 49 |
| 2 | A clinical and long-term follow-up study of perioperative sequential triple therapy for gastric cancer显示文摘INTRODUCTIONAlthough the long-term postoperative survival rateof gastric cancer(GC) patients has been improvedsignificantly since the local dissection of lymph nodewas widely used in China,yet the low curativeresection rate and the high recurrence rate fromperitoneal and hepatic metastases hinder it fromfurther improvement.To alter the currentunsatisfactory status of GC treatment,a | Zou SC Qiu HS Zhang CW Tao HQ | 2000 | World Journal of Gastroenterology2000，6，2： | 18 |
| 3 | Draft genome of the wheata-genome progenitor Triticum urartu显示文摘 | Ling HQ Zhao S Liu D Wang J Sun H Zhang C Fan H Li D Dong L Tao Y Gao C Wu H Li Y Cui Y Guo X Zheng S Wang B Yu K Liang Q Yang W Lou X Chen J Feng M Jian J Zhang X Luo G Jiang Y Liu J Wang Z Sha Y Zhang B WuH Tang D Shen Q Xue P Zou S Wang X Liu X Wang F Yang Y An X Dong Z Zhang K Zhang X Luo MC Dvorak J Tong Y Wang J Yang H Li Z Wang D Zhang A Wang J | 2013 | Nature2013，469，7443： | 1 |
| 4 | Singnificance of vascular endothelial growth factor messenger RNA expression in gastric cancer显示文摘 | Lin YZ | 1998 | World J Gastroentero1998，410，： | 1 |
| 5 | Microribonucleic acids and gastric cancer 显示文摘 | Ma YY Tao HQ | 2012 | Cancer Sci2012，103，4： | 1 |
| 6 | Detection of serum level of TSGF,CA242 and CA19 -9 in pancereatic cancer显示文摘 | Jiang XT Tao HQ Zou SC | 2004 | Hepatobiliary Pancereat Dis Int2004，3，3： | 1 |
| 7 | Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin 显示文摘 | He X J Tao HQ Hu ZM | 2014 | Can- cer Sci2014，105，11： | 1 |
| 8 | Effects of goal-directed fluid therapy with different lactated Ringer's:hydroxyethyl starch ratios in hemorrhagic shock dogs显示文摘 | Tao JP Huang QQ Huang HQ | 2015 | Genet Mol Res2015，14，2： | 1 |
| 9 | Overexpression of matrix metaUoproteinase 11 in human gastric carcinoma and its clinicopathologic significance 显示文摘 | ZHAO ZS CHU YQ YE ZY WANG YY TAO HQ | 2010 | Hum Pathol2010，41，5： | 1 |
| 10 | Evaluation of REG4 for early diagnosis and prognosis of gastric cancer显示文摘 | Tao HQ He X J Ma YY | 2011 | Hum Patho12011，10，42： | 1 |
| 11 | Characterization of the interaction between AStrocytes and encephalitogenic lymphocytes during the de- velopment of experimental autoimmune encephalitomyelitis (EAE) in mice显示文摘 | Yang JF Tao HQ Liu YM | 2012 | Clin Exp Imnmnol2012，170，3： | 1 |
| 12 | HP-β-CD-PLGA nanoparticles improve the penetration and bioavailability of puerarin and enhance the therapeutic effects on brain ischemia-reperfusion injury in rats显示文摘 | Tao HQ Meng Q Li MH | 2013 | Naunyn Schmiedebergs Arch Pharmacol2013，386，1： | 1 |
| 13 | Overexpression of vascular endothelial growth factor by MCF-7 breast cancer cells promotes estrogen-independent tumor growth in vivo 显示文摘 | Guo P Fang Q Tao HQ | 2003 | Cancer Res2003，63，15： | 1 |
| 14 | Influence factors of ser-um fibrosis markers in liver fibrosis显示文摘 | Tao J Peng HQ Cai WM | 2003 | World J GastroenterolJ2003，9，6： | 1 |
| 15 | Characterization of the interac- tion between astrocytes and encephalitogenic lymphoeytes during the development of experimental autoimmune enccphalitomyelitis (EAE) in mice显示文摘 | Yang JF Tao HQ Liu YM | 2012 | Clin Exp Immunol2012，170，3： | 1 |
| 16 | Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2 显示文摘 | Hu B Guo P Fang Q Tao HQ | 2003 | Proc Natl Acad Sci USA2003，100，15： | 1 |
| 17 | Overexpression of vascular endot- helial growth factor by MCF - 7 breast cancer cells promotes estrogen-independent tumor growth in vivo显示文摘 | Guo P Fang Q Tao HQ | 2003 | Cancer Res2003，63，15： | 1 |
| 18 | Characterization of the interaction between astroeytes and eneephalitogenic lymphocytes during the development of experimental autoimrnune encephalitomyelitis (EAE) in mice显示文摘 | Yang JF Tao HQ Liu YM | 2012 | Clin Exp Immunol2012，170，3： | 1 |
| 19 | Evaluation of RegIV forearly diag- nosis and prognosis of gastric cancer 显示文摘 | Tao HQ He XJ Ma YY | 2011 | Hum Pathol2011，42，10： | 1 |
| 20 | Effects of different storage conditions on chemical and physical properties of white mushrooms after vacuum cooling显示文摘 | TAO F ZHANG M YU HQ | | 0，，03： | 1 |
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