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| 1 | Transradial versus transfemoral access for anterior circulation mechanical thrombectomy: analysis of 375 consecutive cases显示文摘Objective To compare transradial artery access(TRA)to the gold standard of transfemoral artery access(TFA)in mechanical thrombectomy(MT)for stroke caused by anterior circulation large vessel occlusion.Methods The clinical outcomes,procedural speed,angiographic efficacy and safety of both techniques were analysed in 375 consecutive cases over an 18-month period in a high volume statewide neurointerventional service.Results There was no significant difference in patient characteristics,stroke parameters,imaging techniques or intracranial techniques.The median time elapsed between CT scanning and reperfusion was 96.5 min(IQR 68-123)in the TFA group and 95 min(IQR 68-123)in the TRA group(p=0.456).Of 336 patients who were independent at presentation 58%(124/214)of the TFA group and 67%(82/122)of the TRA group had a modified Rankin score of 0-2 at 90-day follow-up(p=0.093).Cross-over from radial to femoral was 4.6%(4/130)compared with 1.6%cross-over from femoral to radial(4/245),but did not meet the predetermined level of statistical significance(OR2.92,95% CI 0.81 to 10.52,p=0.088) and did not impact median procedural speed.Adequate angiographic reperfusion,first pass reperfusion,embolisation to new territory and symptomatic intracranial haemorrhage were similar in both groups.There was a significant difference in major access site complications requiring an additional procedure.None of the TRA cases had a major access site complication but 6.5%(16/245)of the TFA cases did(p=0.003).Conclusion This study suggests that using TRA for anterior circulation MT is fast,efficacious,safe and not inferior to the gold standard of TFA. | Timothy John Phillips Matthew Thomas Crockett Gregory D Selkirk Ruchi Kabra Albert Ho Yuen Chiu Tejinder Singh Constantine Phatouros William McAuliffe | 2021 | Stroke & Vascular Neurology2021，6，2： | 7 |
| 2 | Mechanical thrombectomy with the S olitaire AB device in large intracerebral artery occlusions显示文摘 | John J McCabe Timothy J Phillips Con Phatouros Tejinder Singh David Blacker Graeme J Hankey William McAuliffe | 2012 | Journal of Medical Imaging and Radiation Oncology2012，，2： | 2 |
| 3 | Flow behavior and functional properties of barley and oat water-soluble β-D-glucan rich extractions 显示文摘 | Tejinder S Bhupinder K Harinder K | 2000 | International Journal of Food Properties2000，3，2： | 1 |
| 4 | Control of crystal size and distribution of zeolite A 显示文摘 | TEJINDER B PAUL F PANAGIOTIS G | 2001 | lnd Eng Chem Res2001，40，： | 1 |
| 5 | Effect of Porous Activated Charcoal Reinforcement on Mechanical and In-Vitro Biological Properties of Polyvinyl Alcohol Composite Scaffolds显示文摘The present work focused on developing an innovative composite material by reinforcing polymer matrix with highly porous activated charcoal. Polyvinyl alcohol-activated charcoal(PVA-AC) composite scaffolds were developed by varying the AC concentrations(0, 0.5, 1, 1.5, 2 and 2.5 wt%) in PVA matrix by freeze drying method. The developed scaffolds were characterized for their physicochemical, mechanical and in-vitro biological properties. In addition, the effect of AC on the attachment, proliferation and differentiation of osteoblast MG 63 cells was evaluated by scanning electron microscopy(SEM), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay, alkaline phosphatase(ALP) activity assay and alizarin red stain-based(ARS) assay. All the PVA-AC composite scaffolds exhibited good bioactivity, hemocompatibility and protein adsorption properties. The scaffolds with high AC concentration(2.5 wt%) showed controlled drug release kinetics that are suitable for long term healing. The mechanical properties of all the PVA-AC composite scaffolds were improved when compared to the pure PVA scaffold. The high porosity, swelling degree and hydrophilicity of PVA-AC composite scaffolds facilitated cell attachment and proliferation. This is due to porous AC present in the sample that supported the osteoblast differentiation and formed mineralized nodules without the addition of any extra agents. From the above studies, it can be concluded that PVA-AC composite scaffolds are promising biomaterials for bone tissue engineering applications. | Tejinder Kaur Arunachalam Thirugnanam | 2017 | Journal of Materials Science & Technology2017，33，7： | 1 |
| 6 | HPLC in Characterization of hemoglobin profile in thalassemia syndromes and hemoglobinopathies:a clinicohematological correlation显示文摘 | Rachna K Tejinder S Nita K | 2015 | Indian Journal of Hematology and Blood Transfusion2015，31，1： | 1 |
| 7 | Changes in megakaryocytes in case of thrombocytopenia:bone marrow aspiration and biopsy analysis显示文摘 | Tejinder SB Sonam S Mridu M | 2013 | J Clin Diagn Res2013，7，3： | 1 |
| 8 | HPLC in characterization of hemoglobin profile in thalassemia syndromes and hemoglobinopathies:a clinicohematological correlation显示文摘 | Rachna K Tejinder S Nita K | 2015 | Indian Journal of Hematology and Blood Transfusion2015，31，1： | 1 |
| 9 | Control of crystal size and distribution of zeolite A显示文摘 | Tejinder Brar Paul France Panagiotis G Smirniotis | 2001 | Ind Eng Chem Res2001，40，： | 1 |
| 10 | IgA nephropathy in psoriasis显示文摘 | Tejinder S Marjorie F John J | 1998 | Am J Nephrol1998，18，： | 1 |
| 11 | Yield and nitrogen dynamics in a rice-wheat system using green manure and inorganic fertilizer 显示文摘 | Milkha S A Tejinder S K John W D | 2000 | Soil Science Soeical Am2000，84，5： | 1 |
| 12 | Removal of Rhodamine-B by adsorption on walnut shell charcoal显示文摘 | Sumanjit W Tejinder P S Kansal I | 2008 | Journal of Surface Science and Technology2008，24，34： | 1 |
| 13 | Extraction of starch from hulled and hull-less barley with papain and aqueous sodium hydroxide显示文摘 | Tejinder P S·S | 2014 | Journal Food Science of Technology2014，51，12： | 1 |
| 14 | The usefulness of Mini Clinical Evaluation Exercise as a learning tool in different pediatric clinical settings显示文摘 | Atul Goel Tejinder Singh | 2015 | Int J Appl Basic Med Res2015，5，1： | 1 |
| 15 | Cultural Dilemmas and Displacements of Immigrants in JhumpaLahiri's The Namesake 显示文摘 | Kaur Tejinder | 2004 | The Journal of Indian writing in English2004，，2： | 1 |
| 16 | Preparation and characterization of films using barley and oat β-glucan extracts显示文摘 | Tejinder S | 2003 | Cereal Chem2003，80，： | 1 |
| 17 | First-principles theoretical analysis of dopant adsorption and diffusion on surfaces of ZnSe nanocrystals显示文摘 | Tejinder Singh Moontziaris T J Dimitrios Maroudas | 2008 | Chemical Physics Letters2008，462，： | 1 |
| 18 | Retrospecting the concept and industrial significance of LAB bacteriocins显示文摘Ever increasing demand for natural products with minimum chemical additives has necessitated the search for innovative green,potent,environment friendly,natural substitutes for prolonging the shelf life of food products.The lactic acid bacteria(LAB)are a group of Gram-positive microorganisms with great biotechnological potential in the food industry.To reduce pathogen invasion,they can produce inhibitory compounds(bacteriocins,organic acids,hydrogen peroxide,diacetyl,and carbon dioxide).LAB-bacteriocin are proteinaceous antimicrobial molecules with a diverse genetic origin,post-translationally modified or not,that can help the producer organism to outcompete other bacterial species.In addition,they are emerging as a novel wave of potential antibiotics with potent in vitro and in vivo activities.Moreover,LAB-bacteriocin serves as an effective method of natural bio preservation in the food industry and enables the reduction of other costly or user-unfriendly treatments while increasing the product self-life.Therefore,this article provides a recapitulation of classification of bacteriocins,potential of LAB to produce different bacteriocins,their biology,and purification methods.Additionally,it will give a critical snapshot of industrial applications of LAB-bacteriocin as a starter culture,preservative,antibiotic,and probiotics,etc. | Sneh Punia Bangar Vandana Chaudhary Tejinder P.Singh Fatih Ozogul | 2022 | Food Bioscience2022，46，2： | 0 |
| 19 | Immunogenicity and protective efficacy of DNA vaccine against visceral leishmaniasis in BALB/c mice显示文摘当前的学习被设计对鼠科的内脏的 leishmaniasis 基于 gp63 和 Hsp70 检验 DNA 疫苗的保护的功效。生来的 BALB/c 老鼠与个别地并且在联合编码 gp63 和 Hsp70 的 T 房间 epitopes 的 pcDNA3.1 (+) 在三个星期的间隔皮下地被使免疫两次。动物与利什曼原虫 donovani 的 107 promastigotes intracardially 被质问 10 天柱子免疫并且牺牲了 1, 2 和 3 月柱子挑战。使免疫的动物揭示了重要减小(P <0.05 ) 在脾、肝的寄生虫负担作为与感染的控制相比。在寄生虫负担的最大的减小(P <0.05 ) 在与 pcDNA/gp63 和 pcDNA/Hsp70 的联合对待的动物被观察。也显示出的这些动物提高了 DTH 反应,增加的 IgG2a,提高的 Th1 cytokines (IFN-γ并且 IL-2 ) 并且减少的 IgG1 和 IL-10 层次。因此,与鸡尾酒疫苗使免疫的老鼠与与单个抗原使免疫的那些相比展出了显著地更大的保护。 | Sukhbir Kaur Tejinder Kaur Jyoti Joshi | 2016 | The Journal of Biomedical Research2016，30，4： | 0 |
| 20 | Immunogenicity and efficacy of recombinant 78 kDa antigen of Leishmania donovani formulated in various adjuvants against murine visceral leishmaniasis显示文摘Objective: To analyze the protective efficacy of recombinant 78 kDa antigen of Leishmania donovani in combination with two adjuvants, that is, cationic liposomes or MPL-A against visceral leishmaniasis in BALB/c mice. Methods: The genomic DNA of promastigotes was isolated and 583 bp of T cell epitopes of gene encoding 78 k Da was amplified using specific primers. The amplified gene was cloned into p ET28 c, transformed into Escherichia coli BL21(DE3) and got expressed after IPTG induction. The recombinant protein was then purified using Ni-NTA and named r78. Three groups of mice were immunized with 10 μg of r78 plus MPL-A, r78 encapsulated in positively charged liposomes and control animals immunized with PBS. Two booster doses were given with the respective vaccine at an interval of 2 weeks each. Mice were challenged with 1×107 Leishmania promastigotes and sacrificed on different post infection/challenge days. Results: Immunization with r78 along with MPL-A and liposomeencapsulated r78 brought a significant reduction in parasite load. In comparison to the infected controls, the parasite load declined by 96.2% in mice immunized with r78 plus MPL-A and 97.23% in animals immunized with liposome-encapsulated r78. The immunized animals also exhibited profound DTH response. The serum antibody responses increased from 15 to 90 days post infection/challenge. Immunized animals showed greater IgG2 a levels and lesser Ig G1 levels in comparison to the infected controls. The splenocytes from immunized mice were cultured, stimulated with r78 and analyzed for cytokine profile. The levels of IL-2 and IFN-γ were greater in immunized animals as compared to control mice. Conclusions: The study proves that r78 in combination with suitable adjuvants is a potential vaccine candidate and may be instrumental in control of visceral leishmaniasis. | Rajeev Nagill Tejinder Kaur Jyoti Joshi Sukhbir Kaur | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，7： | 0 |
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