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| 1 | Percutaneous closure of secundum type atrial septal defects:More than 5-year follow-up显示文摘AIM: To investigate long-term efficacy of two different devices more than five years after percutaneous atrial septal defect(ASD) closure in adults.METHODS: All patients who underwent percutaneous closure of an ASD in the St. Antonius Hospital, Nieuwegein, The Netherlands, between February 1998 and December 2006 were included. Percutaneous closure took place under general anaesthesia and transesophageal echocardiographic moni toring. Transthoracic echocardiography(TTE) was performed 24 h post-procedure to visualize the device position and to look for residual shunting using color Doppler. All complications were registered. All patients were invited for an outpatient visit and contrast TTE more than 5-years after closure. Efficacy was based on the presence of a residual right-to-left shunt(RLS), graded as minimal, moderate or severe. The presence of a residual left-to-right shunt(LRS) was diagnosed using color Doppler, and was not graded. Descriptive statistics were used for patients' characteristics. Univariate analysis was used to identify predictors for residual shunting.RESULTS: In total, 104 patients(mean age 45.5 ± 17.1 years) underwent percutaneous ASD closure using an Amplatzer device(ASO) in 76 patients and a Cardioseal/Starflex device(CS/SF) in 28 patients. The mean follow-up was 6.4 ± 3.4 years. Device migration occurred in 4 patients of whom two cases occurred during the index hospitalization(1 ASO, 1 CS/SF). The other 2 cases of device migration occurred during the first 6 mo of follow-up(2 CS/SF). The recurrent thrombo-embolic event rate was similar in both groups: 0.4% per follow-up year. More than 12 mo post-ASD closure and latest follow-up, new-onset supraventricular tachyarrhythmia's occurred in 3.9% and 0% for the ASO and CS/SF group, respectively. The RLS rate at latest follow-up was 17.4%(minimal 10.9%, moderate 2.2%, severe 4.3%) and 45.5%(minimal 27.3%, moderate 18.2%, severe 0%) for the ASO- and CS/SF groups, respectively. There was no residual LRS in both groups.CONCLUSION: Percutaneous ASD closure has good long-term safety and efficacy profiles. The residual RLS rate seems to be high more than 5 years after closure, especially in the CS/SF. Residual LRS was not observed. | Roel JR Snijder Maarten J Suttorp Jurrien M Ten Berg Martijn C Post | 2015 | World Journal of Cardiology2015，7，3： | 6 |
| 2 | Aspirin responsive platelet thrombophilia in essential thrombocythemia and polycythemia vera显示文摘Essential thrombocythemia(ET) and polycythemia vera(PV) frequently present with erythromelalgia and acrocyanotic complications, migraine-like microvascular cerebral and ocular transient ischemic attacks(MIAs) and/or acute coronary disease. The spectrum of MIAs in ET range from poorly localized symptoms of transient unsteadiness, dysarthria and scintillating scotoma to focal symptoms of transient monocular blindness, transient mono- or hemiparesis or both. The attacks all have a sudden onset, occur sequentially rather than simultaneously, last for a few seconds to several minutes and are usually associated with a dull, pulsatile or migraine-like headache. Increased hematocrit and blood viscosity in PV patients aggravate the microvascular ischemic syndrome of thrombocythemia to major arterial and venous thrombotic complications. Phlebotomy to correct hematocrit to normal in PV significantly reduces major arterial and venous thrombotic complications, but fails to prevent the platelet-mediated erythromelalgia and MIAs. Complete long-term relief of the erythromelalgic microvascular disturbances, MIAs and major thrombosis in ET and PV patients can be obtained with low dose aspirin and platelet reduction to normal, but not with anticoagulation. Skin punch biopsies from the erythromelalgic area show fibromuscular intimal proliferation of arterioles complicated by occlusive plateletrich thrombi leading to acrocyanotic ischemia. Symptomatic ET patients with erythromelalgic microvascular disturbances have shortened platelet survival, increased platelet activation markers β-thromboglobulin(β-TG), platelet factor 4(PF4) and thrombomoduline(TM), increased urinary thromboxane B2(TXB2) excretion, and no activation of the coagulation markers thrombin fragments F1+2 and fibrin degradation products. Inhibition of platelet cyclooxygenase(COX1) by aspirin is followed by the disappearance and no recurrence of microvascular disturbances, increase in platelet number, correction of the shortened platelet survival times to normal, and reduction of increased plasma levels of β-TG, PF4, TM and urinary TXB2 excretion to normal. These results indicate that platelet-mediated fibromuscular intimal proliferation and platelet-rich thrombi in the peripheral, cerebral and coronary end-arterial microvasculature are responsible for the erythromelalgic ischemic complica-tions, MIAs and splanchnic vein thrombosis. Baseline platelet P-selectin levels and arachidonic acid induced COX1 mediated platelet activation showed a highly significant increase of platelet P-selectin expression(not seen in ADP and collagen stimulated platelets), which was significantly higher in JAK2V617 F mutated compared to JAK2 wild type ET. | Jan Jacques Michiels Fibo WJ Ten Kate Peter J Koudstaal Perry JJ Van Genderen | 2013 | World Journal of Hematology2013，2，2： | 4 |
| 3 | Cognitive performance in patients with COPD显示文摘 | Jeroen J.W Liesker Dirkje S Postma Rypko J Beukema Nick H.T ten Hacken Thys van der Molen Roland A Riemersma Ed H van Zomeren Huib A.M Kerstjens | 2003 | Respiratory Medicine2003，，4： | 3 |
| 4 | Quantitative diagnosis of small approximal caries lesions utilizing wavelength-dependent fiber-optic transillumination 显示文摘 | Vaarkamp J Ten B J Verdonschot E H | 1997 | J Dent Res1997，76，4： | 2 |
| 5 | Extended Transthoracic Resection Compared With Limited Transhiatal Resection for Adenocarcinoma of the Mid/Distal Esophagus: Five-Year Survival of a Randomized Clinical Trial显示文摘 | Jikke M. T. Omloo Sjoerd M. Lagarde Jan B. F. Hulscher Johannes B. Reitsma Paul Fockens Herman van Dekken Fiebo J. W. ten Kate Huug Obertop Hugo W. Tilanus J Jan B. van Lanschot | 2007 | Annals of Surgery2007，，6： | 2 |
| 6 | Cognitive performance in patients with COPD显示文摘 | Jeroen J.W Liesker Dirkje S Postma Rypko J Beukema Nick H.T ten Hacken Thys van der Molen Roland A Riemersma Ed H van Zomeren Huib A.M Kerstjens | 2003 | Respiratory Medicine2003，，4： | 2 |
| 7 | The most likely precursor of gammacerane,occurs ubiquitously in marine sediments显示文摘 | TEN HAVEN H L ROHMER M RULLKTTER J | 1989 | Geochimica et Cosmochimica Acta1989，53，11： | 1 |
| 8 | What is the differ- ence between IgA nephropathy and Henoch-Schonlein purpura nephritis 显示文摘 | Jean Claude Davin Ineke J Ten Berge | 2001 | Kidney Int2001，59，3： | 1 |
| 9 | Contraceptive responses of mice immunized with purified recombination mouse zona pellucida subunit3(mZP3) proteins显示文摘 | Hardy C M Ten Have J F Pekin J | 2003 | Reproduction2003，126，1： | 1 |
| 10 | Restricted utility of the pristane/phytane ratio as a palaeoenvironmental indicator显示文摘 | ten Haven H L de Leeuw J W Rullkotter J | 1987 | Nature1987，330，6149： | 1 |
| 11 | Time to metabolic atrophy after permanent prostate seed implantation based on magnetic resonance spectroscopic imaging显示文摘 | Pickett B Ten Haken RK Kurhanewiez J | 2004 | Int J Radiat Oncol Biol Phys2004，59，3： | 1 |
| 12 | Chronic sinusitis in severe asthma is related to sputum eosinophilia显示文摘 | TEN BRINKE A GROOTENDORST D C SCHMIDT J T | 2002 | J Allergy Clin Immunol2002，109，： | 1 |
| 13 | An evaluation of whole-farm nitrogen balances and related indices for efficient nitrogen use显示文摘 | Schroder J J Aarts H F M Ten Berge H F M | 2003 | European Journal of Agronomy2003，20，12： | 1 |
| 14 | Land use effects on soil N, P, C and pH persist over 40 - 80 years of forest growth on agricul- tural soils 显示文摘 | Falkengren - Grerup U ten Brink D J Brunet J | 2006 | Forest Ecology and Management2006，225，： | 1 |
| 15 | On the Bose-Einstein condensation显示文摘 | DEGROOT S R HOOYMAN G J TEN SELDAM C A | 1950 | Proc R Soc London Ser A1950，203，22： | 1 |
| 16 | An evaluation of whole-farm nitrogen balances and related indices for efficient nitrogen use显示文摘 | Scroder J J Aarts H F M Ten Berge H F M | 2003 | European Journal of Agronomy2003，20，12： | 1 |
| 17 | Conofocal microscopy study of undisturbed and chlorhexidine-treated dental biofilm显示文摘 | Zaura-Arite E van Marle J ten Cate JM | 2001 | J Dent Res2001，80，5： | 1 |
| 18 | Child dental fear and general emotional problems: a pilot study显示文摘 | Krikken J B Ten Cate J M Veerkamp J S | 2010 | Official Journal of the European Academy of Paediatric Dentistry2010，11，6： | 1 |
| 19 | Thermal behavior of chro- mium electroplating sludge显示文摘 | ESPINOSA D C R TEN RIO J A S | 2001 | Waste Management2001，21，4： | 1 |
| 20 | Transgenic expression of pear PGIP in tomato limits fungal colonization 显示文摘 | Powell A L T van Kan J ten Have A | 2000 | Molecular Plant-Microbe Interaction2000，13，： | 1 |
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