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| 1 | Sentinel node navigation surgery in gastric cancer: Current status显示文摘The theory behind using sentinel node mapping and biopsy in gastric cancer surgery, the so-called sentinel node navigation surgery, is to limit the extent of surgi-cal tissue dissection around the affected organ and subsequently the accompanied morbidity. However, ob-stacles on the clinical correspondence of sentinel node navigation surgery in everyday practice have occasion-ally alleviated researchers' interest on the topic. Only recently with the widespread use of minimally invasive surgical techniques, i.e., laparoscopic gastric cancer resections, surgical community's interest on the topic have been unavoidably reflated. Double tracer methods appear superior compared to single tracer techniques. Ongoing research is now focused on the invention of new lymph node detection methods utilizing sophisti-cated technology such as infrared ray endoscopy, flo-rescence imaging and near-infrared technology. Despite its notable limitations, hematoxylin/eosin is still the mainstay staining for assessing the metastatic status of an identified lymph node. An intra-operatively verified metastatic sentinel lymph node will dictate the need for further conventional lymph node dissection. Thus, laparoscopic resection of the gastric primary tumor combined with the appropriate lymph node dissection as determined by the process of sentinel lymph node status characterization represents an option for early gastric cancer. Patients with T3 or more advanced dis-ease should still be managed conventionally with resec-tion plus standard lymph node dissection. | Dimitrios Symeonidis George Koukoulis Konstantinos Tepetes | 2014 | World Journal of Gastrointestinal Surgery2014，6，6： | 9 |
| 2 | colorectal 癌症阶段特征上的 antiplatelet 治疗的影响显示文摘 AIM:To evaluate whether antiplatelet medication leads to an earlier stage colorectal cancer(CRC) diagnosis.METHODS:From January 2002 until March 2010,patients that presented to our institution with the initial diagnosis of CRC and were submitted to an open curative CRC resection or a palliative procedure were retrospectively reviewed.Exclusion criteria were the use of antithrombotic medication,i.e.,coumarins,and appendiceal malignancies.Data acquired from medical files included age,gender,past medical history,antithrombotic treatment received prior to endoscopic diagnosis,preoperative imaging staging,location of the tumor,surgical and final histopathological report.Patients that did not receive any antithrombotic medication prior to the endoscopic diagnosis comprised the control group of the study,while patients that were on antiplatelet medication comprised the antiplatelet group.Primary end point was a comparison of CRC stage in the two groups of the study.CRC presenting symptoms and the incidence of each cancer stage in the two groups were also evaluated.RESULTS:A total of 387 patients with the diagnosis of CRC were submitted to our department for further surgical treatment.Ninety-eight patients(25.32%),with a median age of 71 years(range 52-91 years),were included in the antiplatelet group,while 289(74.67%) patients,with a median age of 67 years(range 4190 years),were not in any thrombosis prophylaxis medication(control group).Thirty-one patients were treated with some kind of palliative procedure,either endoscopic,such as endoscopic stent placement,or surgical,such as de-compressive colostomy or deviation.Coronary disease(77.55%-76 patients),stroke recurrence prevention(14.28%-14 patients) and peripheral arterial disease(8.16%-8 patients) were the indications for the administration of antiplatelet treatment(aspirin,clopidogrel,ticlopidine or dipyridamole) in the antiplatelet group.All patients on aspirin treatment received a dosage of 100 mg/d,while the minimum prophylactic dosages were also used for the rest of the antiplatelet drugs.Investigation of an iron deficiency anemia(147 patients),per rectum blood loss(84 patients),bowel obstruction and/or perforation(81 patients),bowel habits alterations(32 patients),nonspecific symptoms,such as weight loss,intermittent abdominal pain and fatigue,(22 patients) or population screening(21 patients) were the indications for the endoscopic investigation in both groups.Bleeding,either chronic presenting as anemia or acute was significantly higher(P = 0.002) for the antiplatelet arm of the study(71 patients-72.4% of the antiplatelet group vs 160 patients-55.3% of the control group).The mean tumor,node and metastasis stage was 2.57 ± 0.96 for the control group,2.27 ± 0.93 for the antiplatelet group(P = 0.007) and 2.19 ± 0.92 for the subgroup of patients taking aspirin(P = 0.003).The incidence of advanced disease(stage Ⅳ) was lower for the antiplatelet group of the study(P = 0.033).CONCLUSION:The adverse effect of bleeding that is justifiably attached to this drug category seems to have a favorable impact on the staging characteristics of CRC. | Dimitrios Symeonidis Georgios Koukoulis Grigorios Christodoulidis Ioannis Mamaloudis Ioannis Chatzinikolaou Konstantinos Tepetes | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，9： | 3 |
| 3 | Liposarcoma of the stomach: A rare case report显示文摘Liposarcoma is the most common soft tissue sarcoma and accounts for 15%-20% of all mesenchymal malignancies. The tumor occurs most frequently in the limbs, retroperitoneum and rarely has a visceral location. We report a case of a gastric liposarcoma in a male patient. A 68 years old male patient was admitted to hospital for abdominal discomfort and fullness lasting for a month. He reported rare episodes of vomiting. The CT examination revealed a large epigastric mass (8 cm x 4 cm) involving the lesser curvature of the stomach, in contact with the pancreas and gallbladder. Fatty areas within the mass were evident. A total gastrectomy together with cholecystectomy was performed. The histopathological diagnosis was a well differentiated liposarcoma. The patient did not undergo any adjuvant treatment, he is under close follow up and two years later he is disease free. We report this case due to the rarity of this tumor in the stomach (nine cases reported in the literature). | Konstantinos Tepetes Gregory Christodoulidis Michael E Spyridakis Maria Nakou George Koukoulis Konstantinos Hatzitheofilou | 2007 | World Journal of Gastroenterology2007，13，30： | 3 |
| 4 | Bile leakage vollowing T-tube removal in orthotopic liver transplantation显示文摘 | TEPETES K KARAVIAS D FELEKOURAS E | 1999 | Hepato-gastroenterology1999，46，： | 1 |
| 5 | Bile leakage following T-tube removal in orthotopic liver transplantation显示文摘 | TEPETES K KARAVIAS D FELEKOURAS E | 1999 | Hapatogastroenterology1999，46，5： | 1 |
| 6 | bcl-2 and BAX expression and cell proliferation,after partial hepatectomy with and without ischemia,on cholestatic liver in rats:an experimental study显示文摘 | Karavias DD Tsamandas AC Tepetes K | 2003 | J Surg Res2003，110，2： | 1 |
| 7 | Bile leakage following T-tube removal in orthotopic liver transplantation显示文摘 | Tepetes K Karavias D Felekouras E | 1999 | Hepatogastroenterology1999，46，： | 1 |
| 8 | Bile leakage following T-tube removal in orthotopic liver transplantation显示文摘 | Tepetes K Karavias D Felekouras E | 1999 | Hapatogastroenterology1999，46，5： | 1 |
| 9 | Bile leakage following T-tube removal in orthotopic liver transplantation显示文摘 | TEPETES K KARAVIAS D FELEKOURAS E | 1999 | Hepatogastroenterology1999，46，： | 1 |
| 10 | Pudendal nerve block versus local anesthesia for harmonic Scalpel hemor- rhoidectomy: aprospective randomized study 显示文摘 | Tepetes K Symeonidis D Christodoulidis G | 2010 | Teeh Colo- proctol2010，，： | 1 |
| 11 | Embolization of a Giant Hepatic Hemangioma Prior To Urgent Liver Resection. Case Report and Review of the Literature显示文摘 | K. Vassiou H. Rountas P. Liakou D. Arvanitis I. Fezoulidis K. Tepetes | 2007 | CardioVascular and Interventional Radiology2007，，4： | 1 |
| 12 | Bile leakage following T- tube removal in orthotopic liver transplantation 显示文摘 | Tepetes K Karavias D Felekouras E | 1999 | Hepatogastroenterology1999，46，： | 1 |
| 13 | Tissue preserving hepateetomy by a vessel sealing de- vice 显示文摘 | TEPETES K CHRISTODOULIDIS G SPYRIDAKIS E M | 2008 | J Surg Oncol2008，97，2： | 1 |
| 14 | Tissue preserving hepateetomy by a vessel sealing device 显示文摘 | Tepetes K Christodoulidis G Spyridakis EM | 2008 | J Surg Oneol2008，97，2： | 1 |
| 15 | Hepatitis B virus and intrahepatic eholangiocarcinoma 显示文摘 | Gatselis NK Tepetes K Loukopoulos A | 2007 | Cancer Invest2007，25，： | 1 |
| 16 | Bile leakage following T-tube removal in orthotopic liver transplantation显示文摘 | Karavias D Felekouras E | 1999 | Hepatogastroenterology1999，46，25： | 1 |
| 17 | BCL-2 and BAX expression and cell proliferation,after partial hepatectomy with and without ischemia,on cholestatic liver in rats: an experimental study显示文摘 | Karavias D Tsamandas AC Tepetes K | 2003 | J Surg Res2003，110，2： | 1 |
| 18 | Hepatitis B Virus and Intrahepatic Cholangiocarcinoma显示文摘 | Nikolaos K. Gatselis Konstantinos Tepetes Argirios Loukopoulos Katerina Vasiou Athanasios Zafiriou Chrisoula Gioti Georgios N. Dalekos | 2007 | Cancer Investigation2007，，1： | 1 |
| 19 | Pu- dendal nerve block versus local anesthesia for harmonic scalpel hemorrhoidectomy: a prospective randomized study显示文摘 | Tepetes K Symeonidis D Christodoulidis G | 2010 | Tech Coloproctol2010，14，11： | 1 |
| 20 | Embolization of a Giant Hepatic Hemangioma Prior To Urgent Liver Resection. Case Report and Review of the Literature显示文摘 | K. Vassiou H. Rountas P. Liakou D. Arvanitis I. Fezoulidis K. Tepetes | 2007 | CardioVascular and Interventional Radiology2007，，4： | 1 |
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