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| 1 | Current and future medical therapeutic strategies for the functional repair of spinal cord injury显示文摘Spinal cord injury(SCI) leads to social and psychological problems in patients and requires costly treatment and care. In recent years, various pharmacological agents have been tested for acute SCI. Large scale, prospective, randomized, controlled clinical trials have failed to demonstrate marked neurological benefit in contrast to their success in the laboratory. Today, the most important problem is ineffectiveness of nonsurgical treatment choices in human SCI that showed neuroprotective effectsin animal studies. Recently, attempted cellular therapy and transplantations are promising. A better understanding of the pathophysiology of SCI started in the early 1980 s. Research had been looking at neuroprotection in the 1980 s and the first half of 1990 s and regeneration studies started in the second half of the 1990 s. A number of studies on surgical timing suggest that early surgical intervention is safe and feasible, can improve clinical and neurological outcomes and reduce health care costs, and minimize the secondary damage caused by compression of the spinal cord after trauma. This article reviews current evidence for early surgical decompression and nonsurgical treatment options, including pharmacological and cellular therapy, as the treatment choices for SCI. | Tevfik Y?lmaz Erkan Kaptano?lu | 2015 | World Journal of Orthopedics2015,6,1: | 19 |
| 2 | Current and future surgery strategies for spinal cord injuries显示文摘Spinal cord trauma is a prominent cause of mortality and morbidity. In developed countries a spinal cord injury(SCI) occurs every 16 min. SCI occurs due to tissue destruction, primarily by mechanical and secondarily ischemic. Primary damage occurs at the time of the injury. It cannot be improved. Following the primary injury, secondary harm mechanisms gradually result in neuronal death. One of the prominent causesof secondary harm is energy deficit, emerging from ischemia, whose main cause in the early stage, is impaired perfusion. Due to the advanced techniques in spinal surgery, SCI is still challenging for surgeons. Spinal cord doesn't have a self-repair property. The main damage occurs at the time of the injury primarily by mechanical factors that cannot be improved. Secondarily mechanisms take part in the following sections. Spinal compression and neurological deficit are two major factors used to decide on surgery. According to advanced imaging techniques the classifications systems for spinal injury has been changed in time. Aim of the surgery is to decompress the spinal channel and to restore the spinal alinement and mobilize the patient as soon as possible. Use of neuroprotective agents as well as methods to achieve cell regeneration in addition to surgery would contribute to the solution. | Sedat Dalbayrak Onur Yaman Tevfik Y?lmaz | 2015 | World Journal of Orthopedics2015,6,1: | 7 |
| 3 | Carrier frequency offset compensation with successive cancellation in uplink OFDMA systems显示文摘 | Tevfik Y Huseyin A | 2007 | IEEE Trans on Wireless Commun2007,6,10: | 1 |
| 4 | Carrier frequency offset compensation with successive cancellation in uplink OFDMA systems显示文摘 | Tevfik Y Huseyin A | 2007 | IEEE Transactions on Wireless Communications2007,6,10: | 1 |
| 5 | Comparison of three different combination therapies in the treatment of human brucellosis显示文摘 | Ersoy Y Sonmez E Tevfik MR | 2005 | Trop Doct2005,35,4: | 1 |
| 6 | Comparison of three different combination therapies in the treatment of human brucellosis显示文摘 | Ersoy Y Sonmez E Tevfik M R | 2005 | Trop Doct2005,35,4: | 1 |
| 7 | A survey of spectrum sensing algorithms for cognitive radio applications 显示文摘 | Tevfik Y Huseyin A | 2009 | IEEE Communications Surveys & Tutorials2009,11,1: | 1 |
| 8 | Comparison of three different combination therapies in the treatment of human brucellosis 显示文摘 | Ersoy Y Sonmez E Tevfik MR | 2005 | Trop Doct2005,35,4: | 1 |
| 9 | Comparison of three different combination therapies in the treatment of human brucellosis显示文摘 | Ersoy Y Sonmez E Tevfik MR | 2005 | Trop Doct2005,35,4: | 1 |
| 10 | Carrier Frequency Offset Compensation with Successive Cancellation in Uplink OFDMA Systems显示文摘 | Tevfik Y Huseyin A | 2007 | IEEE Trans Wireless Commun2007,6,10: | 1 |
| 11 | Comparison of three different combination therapies in the treatment of human brucellosis显示文摘 | Ersoy Y Sonmez E Tevfik MR | | 0,,04: | 1 |
| 12 | A Survey of Spectrum Algo-rithms for Cognitive Radio Applications显示文摘 | Tevfik Y Huseyin A | | 0,,01: | 1 |
| 13 | Comparison of three different combination t herapies in the treatment of human brucellosis显示文摘 | Ersoy Y Sonmez E Tevfik MR | 2005 | Trop Doct2005,35,4: | 1 |
| 14 | An efficient blind modulation detec-tion algorithm for adaptive OFDM system显示文摘 | Sharath B R Tevfik Y Hiiseyin A | 2003 | VTC2003,3,: | 1 |
| 15 | Comparison of three differentcombination therapies in the treatment of human brucellosis显示文摘 | Ersoy Y Sonmez E Tevfik MR | 2005 | TropDoct2005,35,: | 1 |
| 16 | Comparison of three different combination therapies in the treatment of human brucellosis显示文摘 | Ersoy Y Sonmez E Tevfik MR | 2005 | Trop Doct2005,35,4: | 1 |
| 17 | Carrier frequency offset compensation with successive cancellation in uplink OFDMA systems显示文摘 | Tevfik Y Huseyin A | 2007 | IEEE Trans on Wireless Commun2007,6,10: | 1 |
| 18 | Comparison of three different combination therapies in the treatment of human brucellosis显示文摘 | Ersoy Y Sonmez E Tevfik MR | 2005 | Trop Doct2005,35,4: | 1 |
| 19 | Comparion of three different combionation the treatment of human brucellsis显示文摘 | Ersoy Y Sonmez E Tevfik MR | | 0,,04: | 1 |
| 20 | Comparison of three different combination therapies in the treatment of human brucellosis显示文摘 | Ersoy Y Sonmez E Tevfik MR | 2005 | Trop Doct2005,35,: | 1 |