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| 1 | Different antibiotic susceptibility between antrum and corpus of the stomach,a possible reason for treatment failure of Helicobacter pylori infection显示文摘AIM:To assess whether antibiotic resistance varies between the antrum and corpus of the stomach of patients that are either Helicobacter pylori(H.pylori)therapy-naive or pre-treated.METHODS:H.pylori strains were isolated from antrum and corpus biopsies from 66 patients that received a diagnostic gastroduodenoscopy for variant clinical indications.Antimicrobial susceptibility to amoxicillin,clarithromycin,tetracycline,metronidazole,levofloxacin and rifabutin was tested with the E-test method on IsoSensitest agar with 10 vol%defibrinated horse blood.In patients with a different antibiotic susceptibility pattern between the isolates from the antrum and corpus,DNA fingerprinting via random amplified polymorphic DNA analysis was performed to detect differences among DNA patterns of H.pylori isolates.RESULTS:Primary,secondary and tertiary resistance to clarithromycin was 6.9%,53.8%and 83.3%,retrospectively.Metronidazole and levofloxacin resistance also increased according to the number of previous treatments(17.2%,69.2%,83.3%;13.8%,23.1%,33.3%).Tertiary resistance to rifabutin was detected in12.5%of patients.In none of the 66 patients a resistance against amoxicillin or tetracycline was detectable.Discordant antibiotic susceptibility between antrum and corpus isolates for different antibiotics was seen in 15.2%(10/66)of the patients.Two out of those ten patients were naive to any H.pylori antibiotic treatment.The remaining eight patients previously received at least one eradication therapy.DNA fingerprinting analysis revealed no substantial differences among DNA patterns between antrum and corpus isolates in the majority of patients suggesting an infection with a single H.pylori strain.CONCLUSION:Different antibiotic susceptibility between antrum and corpus biopsies is a common phenomenon and a possible explanation for treatment failure.Resistant H.pylori strains may be missed if just one biopsy from one anatomic site of the stomach is taken for H.pylori susceptibility testing. | Michael Selgrad Ina Tammer Cosima Langner Jan Bornschein Julia Mei?le Arne Kandulski Mariya Varbanova Thomas Wex Dirk Schlüter Peter Malfertheiner | 2014 | World Journal of Gastroenterology2014，20，43： | 10 |
| 2 | 激光诱导击穿光谱技术对冶金样品中钢及炉渣的同时分析显示文摘本研究的初衷是开发一种不均匀冶金样品中钢和炉渣的快速、同时分析方法,以用于工艺控制。该方法基于激光诱导击穿光谱技术(LIBS)。选择激光诱导击穿光谱技术是因为它既可以分析导电材料又可分析非导电材料,并且相对来说不易受样品形状及表面光洁度的影响。产生的不均匀样品包含大量亚毫米级的渣颗粒,这些颗粒在单次LIBS分析中不能从周围的钢里面分离出来。因此提出了一种方法来对样品表面进行行扫描,扫描以大约0.5mm的分辨率和10 mm的步长来进行。激光的脉冲速率为20 Hz,扫描速度为1 mm/s。炉渣颗粒在行扫描中表现为钢的'污染区',在这个区域中有高浓度的一些元素,如钙、铝及硅。基于单点校准,提出了一种数学模型来逐步评定所得出的数据。首先,辨别出'干净'的钢区域,测定出钢的成分;第二步,测定出扫描总长度范围内的平均成分;最后一步,通过差减法计算出炉渣的成分平均值。这种方法被应用于几个多相取样器采集的样品的分析。发现钢中的碳、硅、锰、磷、硫及铝等元素都可被测定,仅有百分之几的相对标准偏差。而在炉渣中,分析的相对标准偏差会更高,几个重要元素在10%左右。这一方法有望进一步被开发应用于更小的非金属夹杂物的快速分析。 | BENGTSON Arne THOMAS Bjork | 2009 | 冶金分析2009，29，2： | 10 |
| 3 | 基于亚波长空间分辨平面太赫兹谐振器的二维频率分辨成像显示文摘利用基于扫描遂道显微成像技术的无孔(散射)近场太赫兹时域显微镜,对由非对称开口谐振环(SRR)构成的频率选择表面(FSS)的单元进行了研究。利用高速非同步光学采样法,在宽频率范围(0.3…1THz)内获得了l/60-l/200的高频独立分辨率的图像显示。该图像给出了谐振环的弧状结构,另外,还显示了谐振环的弧末端周围的信号增强。结果显示,从两个不同弧发出的相对近场信号强度的特性与SRRs本征共振频率是相关联的。 | Arne Thoma Thomas Dekorsy | 2012 | 长春理工大学学报(自然科学版)2012，35，3： | 4 |
| 4 | 基于情境感知的服务系统(英文)显示文摘The paper gives an overview of a recently started research project addressing the question:Can context be exploited to add value to IT-services?Beyond today's way-finding services based on GPS and maps,we believe there is a new class of context-aware pervasive services making good use of a broad range of context information(e.g.identity,time of day,temperature,history as well as relative location of friends and belongings).Last but not least we believe one can find ways of adding value to IT-services by using disembodied conversational agents based on voice,sounds and visual signals integrated into the environment, instead of being guided by explicit directions shown on a display.The project aims at giving both new fundamental insight about the theory behind IT-services,their architecture and user interfaces and at building a number of prototypes demonstrating innovative context-aware pervasive IT-services. | Jφrgen Staunstrup 童缙 郁莲 李伟平 林慧苹 褚伟杰 John Paulin Hansen Arne Glenstrup Thomas Hildebrandt | 2009 | 计算机系统应用2009，18，6： | 3 |
| 5 | 国际卒中遗传学联盟的推荐意见(第2部分):生物样本的采集和储存显示文摘在2003年人类基因组测序以及全基因组基因分型技术发展的共同促进下,人类遗传学的进步已使我们识别出2000多个与性状相关的基因突变。由于这些突变大多数对疾病风险仅有微小的独立影响,因此成功的遗传学研究需要很大的样本量(包含数以千计、万计或者十万计的病例和对照)才能达到足够的研究效能。如此大的样本量积累需要依赖在人类遗传学研究乃至在临床研究中史无前例的大规模国际协作。现在已有许多常见疾病的专病联盟将大量独立机构和合作者联合起来。每个联盟均面临至少2个基本问题:如何整合具有足够数量、同质性和表型质量高的研究样本以及如何储存和分析来自入组受试者的生物样本,有时可能需要在数年间反复进行。 | Thomas W.K.Battey Valerie Valant Sylvia Baedorf Kassis Christina Kourkoulis Chaeyoung Lee Christopher D. Anderson Guido J. Falcone Jordi Jimenez-Conde Israel Fernandez-Cadenas Guillaume Pare Tatjana Rundek Michael L. James Robin Lemmens Tsong-Hai Lee Turgut Tatlisumak Steven J. Kittner Arne Lindgren Farrah J. Mateen Aaron L. Berkowitz Elizabeth G. Holliday Jennifer Majersik 李海峰 姜平 岳耀先 | 2015 | 国际脑血管病杂志2015，23，9： | 2 |
| 6 | Covalent Triazine Frameworks as Heterogeneous Catalysts for the Synthesis of Cyclic and Linear Carbonates from Carbon Dioxide and Epoxides显示文摘 | Jér?me Roeser Kamalakannan Kailasam Arne Thomas | 2012 | ChemSusChem2012，，9： | 1 |
| 7 | Eccrine porocarcinoma of the head : an important differential diagnosis in the elderly patient 显示文摘 | Peter Arne Gerber Klaus-Werner Schuhe Thomas Ruzicka | 2008 | Dermatology2008，216，3： | 1 |
| 8 | Hormonal control of the yolk precursor vitellogenin regulates immune function and longevity in honeybees显示文摘 | Gro V Amdam Zilá L.P Sim?es Arne Hagen Kari Norberg Knut Schr?der ?yvind Mikkelsen Thomas B.L Kirkwood Stig W Omholt | 2004 | Experimental Gerontology2004，，5： | 1 |
| 9 | 纳米结构的炭钌复合物——一种提高超级电容器性能的电极材料(英文)显示文摘报道了一种利用氧化硅模板,裂解简单易得的含钌有机物制备纳米结构炭/钌复合物的方法。在该复合物中,钌纳米颗粒均匀地分布在多孔的炭基体中。该复合物被电氧化所得炭/RuO.2xH2O的超级电容性质明显提高(10mV/s时229F/g )。 | 崔光磊 周新红 智林杰 Arne Thomas Klaus Müllen | 2007 | 新型炭材料2007，22，4： | 1 |
| 10 | Antibiotic susceptibility of Helicobacter pylori in central Germany and its relationship with the number of eradication therapies显示文摘 | Michael Selgrad Julia Meile Jan Bornschein Arne Kandulski Cosima Langner Mariya Varbanova Thomas Wex Ina Tammer Dirk Schlüter Peter Malfertheiner | 2013 | European Journal of Gastroenterology & Hepatology2013，，11： | 1 |
| 11 | Toward stable interfaces in conjugated polymers: Microporous poly( p phenylene) and poly(phenyleneethynylene) based on a spirobifluorene building block显示文摘 | Jens Weber Arne Thomas | 2008 | Journal of American Chemistry Society2008，130，20： | 1 |
| 12 | Reduced-Intensity Allogeneic Transplant in Patients Older Than 55 Years: Unrelated Umbilical Cord Blood Is Safe and Effective for Patients without a Matched Related Donor显示文摘 | Navneet S. Majhail Claudio G. Brunstein Marcie Tomblyn Avis J. Thomas Jeffrey S. Miller Mukta Arora Dan S. Kaufman Linda J. Burns Arne Slungaard Philip B. McGlave John E. Wagner Daniel J. Weisdorf | 2008 | Biology of Blood and Marrow Transplantation2008，，3： | 1 |
| 13 | TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death显示文摘 | Justyna Sosna Susann Voigt Sabine Mathieu Arne Lange Lutz Thon Parvin Davarnia Thomas Herdegen Andreas Linkermann Andrea Rittger Francis Ka-Ming Chan Dieter Kabelitz Stefan Schütze Dieter Adam | 2014 | Cellular and Molecular Life Sciences2014，，2： | 1 |
| 14 | Key Epitopes on the ESAT-6 Atigen Recognized in Mice During the Recall of Protective Immunity to Mycobacterium tuberculosis 显示文摘 | Lise Brandt Thomas Oettinger Arne Holm | 1996 | Immunol1996，157，： | 1 |
| 15 | Large-scale comparative analyses of immunomarkers for diagnostic subtyping of non-small-cell lung cancer biopsies显示文摘 | Arne Warth Thomas Muley Esther Herpel | 2012 | Histopathology2012，61，： | 1 |
| 16 | Esophageal Intraluminal Baseline Impedance Differentiates Gastroesophageal Reflux Disease From Functional Heartburn显示文摘 | Arne Kandulski Jochen Weigt Carlos Caro Doerthe Jechorek Thomas Wex Peter Malfertheiner | 2014 | Clinical Gastroenterology and Hepatology2014，，： | 1 |
| 17 | Feasibility of simultaneous saccharification and juice co-fermentation on hydrothermal pretreated sweet sorghum bagasse for ethanol production显示文摘 | Bernd Rohowsky Thomas H??ler Arne Gladis Edgar Remmele Doris Schieder Martin Faulstich | 2013 | Applied Energy2013，，： | 1 |
| 18 | The presence of Penicillium and Penicillium mycotoxins in food wastes显示文摘 | Thomas R Ida S Arne F | 2004 | International Journal of Food Microbiology2004，90，： | 1 |
| 19 | The prensence of Penicillum and Penicillum mycotoxins in food waste显示文摘 | Thomas Rundberget Ida Skaar Arne Flaoyen | 2004 | International Journal of food icrobiology2004，，90： | 1 |
| 20 | Mapping of the Delayed-Type Hypersensitivity-Inducing Epitope of Secreted Protein MPT64 from Mycobacterium tubercilosis 显示文摘 | Arne Holm Isaac M Mtoni | 1995 | Infection and Immunity1995，63，12： | 1 |
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