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| 1 | 平均动脉压、脉压与全因死亡率的纵向变化:来自71629名未经治疗的正常高值血压参与者的数据显示文摘血压通常包括平稳成分[平均动脉压(mean arterial pressure,MAP)]和波动成分,都可独立预测死亡率。目前还没有针对中心脉压(central pulse pressure,cPP)、肱动脉脉压(brachial pulse pressure,bPP)、MAP的纵向变化与死亡率之间关系的调查。方法:对年龄16~95岁未接受高血压治疗的71 629例参与者进行2次常规检查. | Protogerou AD Vlachopoulos C Thomas F Zhang Y Pannier B Blacher J Safar ME 陈云 | 2018 | 中华高血压杂志2018，26，8： | 4 |
| 2 | A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity显示文摘Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms of protection against reinfection and,thus,for public health policy and vaccine development for COVID-19.In this study,using either live SARS-CoV-2 particles or retroviruses pseudotyped with the SARS-CoV-2 S viral surface protein(Spike),we studied the neutralizing antibody(nAb)response in serum samples from a cohort of 140 SARS-CoV-2 qPCR-confirmed infections,including patients with mild symptoms and also more severe forms,including those that required intensive care.We show that nAb titers correlated strongly with disease severity and with anti-spike IgG levels.Indeed,patients from intensive care units exhibited high nAb titers;conversely,patients with milder disease symptoms had heterogeneous nAb titers,and asymptomatic or exclusive outpatient-care patients had no or low nAbs.We found that nAb activity in SARS-CoV-2-infected patients displayed a relatively rapid decline after recovery compared to individuals infected with other coronaviruses.Moreover,we found an absence of cross-neutralization between endemic coronaviruses and SARS-CoV-2,indicating that previous infection by human coronaviruses may not generate protective nAbs against SARS-CoV-2.Finally,we found that the D614G mutation in the spike protein,which has recently been identified as the current major variant in Europe,does not allow neutralization escape.Altogether,our results contribute to our understanding of the immune correlates of SARS-CoV-2-induced disease,and rapid evaluation of the role of the humoral response in the pathogenesis of SARS-CoV-2 is warranted. | Vincent Legros Solène Denolly Manon Vogrig Bertrand Boson Eglantine Siret Josselin Rigaill Sylvie Pillet Florence Grattard Sylvie Gonzalo Paul Verhoeven Omran Allatif Philippe Berthelot Carole Pélissier Guillaume Thiery Elisabeth Botelho-Nevers Guillaume Millet Jérôme Morel Stéphane Paul Thierry Walzer François-Loïc Cosset Thomas Bourlet Bruno Pozzetto | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 3 | Ultrasonic cavitation indirectly induces single strand breaks in DNA of viable cells in vitro by the action of residual hydrogen peroxide显示文摘 | Miller DL Thomas RM Frazier ME | 1991 | Ultrasound Med Biol1991，17，7： | 1 |
| 4 | Deep burns caused by far-infrared rays in a chiropractic sales centre显示文摘 | Habib ME Punnoose T Thomas C | | 0，，02： | 1 |
| 5 | Covalent Triazine Frameworks as Heterogeneous Catalysts for the Synthesis of Cyclic and Linear Carbonates from Carbon Dioxide and Epoxides显示文摘 | Jér?me Roeser Kamalakannan Kailasam Arne Thomas | 2012 | ChemSusChem2012，，9： | 1 |
| 6 | Metabolic effects of fatty acid-bearing albumin on a proximal tubule cell line 显示文摘 | Thomas ME Morrison AR Schreiner GF | 1995 | AJP - Renal Physiology1995，268，6： | 1 |
| 7 | Tubular changes in early diabetic nephropathy显示文摘 | Thomas MC Burns WC Cooper ME | 2005 | Advances in Chronic Kidney Disease2005，12，2： | 1 |
| 8 | Contribution of Fatty Acid Bearing Album in显示文摘 | Thomas Me | 1993 | Am J Nephron1993，，3： | 1 |
| 9 | Metabolic effects of fatty acid-bearing albumin on a proximal tubule cell line显示文摘 | Thomas ME Morrison AR Schreiner GF | 1995 | AJP-Renal Physiology1995，268，6： | 1 |
| 10 | Lipoprotein(a) in patients with proteinuria显示文摘 | Thomas ME Frestone A Varghese Z | | 0，，05： | 1 |
| 11 | Advanced glycation end products in diabetic nephropathy 显示文摘 | Thomas MC Forbes JM Cooper ME | 2005 | Am J Ther2005，12，6： | 1 |
| 12 | Advanced glycation end products and diabetic nephropathy显示文摘 | Thomas MC Forbes JM Cooper ME | 2005 | American Journal of Therapeutics2005，12，6： | 1 |
| 13 | Tubular changes in early diabetic nephropathy显示文摘 | Thomas MC Burn WC Cooper ME | 2005 | Adv Chronic Kidney Dis2005，12，2： | 1 |
| 14 | Entire Emergent Phenomena and ultiorganizational Coordination in Disasters: Lessons from the Research Literature显示文摘 | Drabek Thomas E and David A Me | 2002 | International Journal of Mass Emergencies and Disasters2002，，2： | 1 |
| 15 | Management of soft tissue sarcoma显示文摘 | Pitcher ME Fish S Thomas JM | 1994 | Br J Surg1994，81，8： | 1 |
| 16 | Into the light? Diabetic nephropa- thy and vitamin D显示文摘 | Thomas Me Cooper ME | 2010 | Lancet2010，376，9752： | 1 |
| 17 | PET/CT with 18F-FLT is unlikely to cause significant hepatorenal or hematologic toxicity显示文摘 | Juweid ME Thomas D Menda Y | 2010 | J Nucl Med2010，51，5： | 1 |
| 18 | Adult bone marrowstromal cells in the embryonic brain :Engraftment,migration,differentiation, and long-term survival显示文摘 | Guillermo ME Akiva JM Thomas M | 2004 | J Neurosci2004，24，19： | 1 |
| 19 | Early detection of ectopic pregnancy visualizing the presence of a tubal ring with ultrasonog raphy formed by emergency physicians显示文摘 | Thoma ME | 2000 | Am J Emerg Med2000，18，4： | 1 |
| 20 | A case-control evaluation of the detection of breast cancer screening in the UK trial of early detection of breast cancer显示文摘 | Moss SM Surmmerley ME Thomas BA | | 0，，05： | 1 |
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