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108篇 您的检索式:作者名="Thome G"
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1Involvement of autophagy in alcoholic liver injury and hepatitis C pathogenesis显示文摘This review describes the principal pathways of macroautophagy (i.e. autophagy), microautophagy and chaperone-mediated autophagy as they are currently known to occur in mammalian cells. Because of its crucial role as an accessory digestive organ, the liver has a particularly robust autophagic activity that is sensitive to changes in plasma and dietary components. Ethanol consumption causes major changes in hepatic protein and lipid metabolism and both are regulated by autophagy, which is significantly affected by hepatic ethanol metabolism. Ethanol exposure enhances autophagosome formation in liver cells, but suppresses lysosome function. Excessive ethanol consumption synergizes with hepatitis C virus (HCV) to exacerbate liver injury, as alcohol-consuming HCV patients frequently have a longer course of infection and more severe manifestations of chronic hepatitis than abstinent HCV patients. Alcohol-elicited exacerbation of HCV infection pathogenesis is related to modulation by ethanol metabolism of HCV replication. Additionally, as part of this mechanism, autophagic proteins have been shown to regulate viral (HCV) replication and their intracel-lular accumulation. Because ethanol induces autophagosome expression, enhanced levels of autophagic proteins may enhance HCV infectivity in liver cells of alcoholics and heavy drinkers.Natalia A Osna Paul G Thomes Terrence M Donohue 2011World Journal of Gastroenterology2011,17,20:5
2Feelings of patients on the waiting list for a kidney transplant显示文摘Flores R V Thome E G 2004Rev Bras En- ferm2004,57,6:1
3Eccentric over load training for patients with chronic Achilles tendon pain a randomized controlled study with reliability testing of the evaluation methods显示文摘Silbemagel K G Thomee R Thomee P 2001Scand J Med Sci Sports2001,11,4:1
4Magneto-optic/ eddy current imaging of aging aircraft: a new NDI technique 显示文摘Fitzpatrick G L Thome D K Skaugset R L 1993Materials Evaluation1993,51,12:1
5Comparison between ADCP and transmissometer measurements of suspended sedi ment concentration显示文摘HOLDAWAY G P THOME P D FLATT D 1999Continental Shelf Research1999,19,3:1
6Soft Reduction of Continuous Cast Billets at Saarstahl显示文摘Thome R Ostheimer V Ney G 2007MPT2007,30,1:1
7Increased interleu- kin (IL)-1 beta messenger ribonucleie acid expression in beta- cells of individuals with type 2 diabetes and regulation of IL-lbeta in human islets by glucose and autostimulation 显示文摘Boni-Schnetzler M Thome J Parnaud G 2008J Clin Endo- erinol Metab2008,93,10:1
8Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration 显示文摘THOME R G PRONK G J PADMANABHAN V 2004Neuroscience2004,127,2:1
9Intranasal delivery of biologics to the central nervous system 显示文摘LOCHHEAD J J THOME R G 2012Adv Drug Deliv Rev2012,64,7:1
10Failing factor associated with osseointegrated dental implant loss显示文摘Montes CC Pereive FA Thome G 2007Implant Dent2007,16,4:1
11Related articles, links hypothermia as a neuroprotective strategy in subarachnoid bemorrhage:a pathopbysiological review focusing on the acute phase显示文摘Thome C Schubert G A Schilling L 2005Neurol Res2005,27,3:1
12The present status of magneto optic eddy current image technology显示文摘FITZPATRICK G L THOME D K SKAUGSET R L 1993Review of Progress in QNDE1993,12,:1
13Increased inter-leukin(IL)-Ibeta messenger ribonucleic acid expression in beta-cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation显示文摘Boni-Schnetzler M Thome J Pamaud G 2008J ClinEndocrinol Metab2008,93,40:1
14Satu-rated flow boiling heat transfer and critical heat flux insmall horizontal flattened tubes 显示文摘Cristiano Bigonha Tibirigd Ribatski G Thome J R 2012International Journalof Heat and Mass Transfer2012,55,2526:1
15Two-phase flow patterns and flow-pattern maps: Fundamentals and applications 显示文摘CHENG L X RIBATSKI G THOME J R 2008Applied Mechanics Reviews2008,61,5:1
16Impacts of spectral band difference effects on radiometric cross-calibration between satellite sensors in the solar-reflective spectral domain显示文摘Teillet P M Fedosejevs G Thome K J 0,,03:1
17Estimation of radiation inter- ceptin by winter wheats from measurements of leat area 显示文摘Thome G N Pearman W D Todd A D 1988Journal Agric sci1988,110,1:1
18State-of-the-art review of flow boiling and two-phase flow of CO2 in macro- and micro-channels 显示文摘Thome J R Ribatski G 2005International Journal of Refrigeration2005,28,8:1
19Magneto-optic/eddy current imaging of aging aircraft:A new NDI technique显示文摘FITZPATRIEK G L THOME D SKAUGSET R 1993Materials Evaluation1993,51,12:1
20An Analysis of Ex- perimental Data and Prediction Methods for Two-phase Frictional Pressure Drop and Flow Boiling Heat Trans- fer in Micro-scale Channels显示文摘Ribatski G Wojtan L Thome J R 2006Experimental Thermal and Fluid Science2006,31,1:1
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