2篇
您的检索式：作者名="Tiandong Che"
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| 1 | Genome-wide analysis reveals selection for Chinese Rongchang pigs显示文摘Livestock have undergone domestication and consequently strong selective pressure on genes or genomic regions that control desirable traits. To identify selection signatures in the genome of Chinese Rongchang pigs, we generated a total of about 170 Gb of DNA sequence data with about 6.4-fold coverage for each of six female individuals. By combining these data with the publically available genome data of 10 Asian wild boars,we identified 449 protein-coding genes with selection signatures in Rongchang pigs, which are mainly involved in growth and hormone binding, nervous system development, and drug metabolism. The accelerated evolution of these genes may contribute to the dramatic phenotypic differences between Rongchang pigs and Chinese wild boars. This study illustrated how domestication and subsequent artificial selection have shaped patterns of genetic variation in Rongchang pigs and provides valuable genetic resources that can enhance the use of pigs in agricultural production and biomedical studies. | Lei CHEN Shilin TIAN Long JIN Zongyi GUO Dan ZHU Lan JING Tiandong CHE Qianzi TANG Siqing CHEN Liang ZHANG Tinghuan ZHANG Zuohua LIU Jinyong WANG Mingzhou LI | 2017 | Frontiers of Agricultural Science and Engineering2017，4，3： | 2 |
| 2 | Snapshot of Structural Variations in the Tibetan Wild Boar Genome at Single-Nucleotide Resolution显示文摘Genomic structural variations(SVs),particularly insertions,deletions and inversions,can contribute to the heterogeneity of millions of nucleotides within a genome,and are likely to make an important contribution to biological diversity and phenotypic variation(Alkan et al.,2011;Bickhart and Liu,2014).With the rapid development of the next-generation sequencing technologies and the new assembly methodologies,the | Lei Chen Long Jin Mingzhou Li Shilin Tian Tiandong Che Qianzi Tang Jing Lan Zhi Jiang Ruiqiang Li Yiren Gu Xuewei Li Jinyong Wang | 2014 | Journal of Genetics and Genomics2014，41，12： | 1 |
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