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| 1 | Cytoreductive surgery and intraperitoneal chemotherapy for colorectal peritoneal metastases显示文摘AIM:To systematically review the available evidence regarding cytoreductive surgery(CRS) and intraperitoneal chemotherapy(IPC) for colorectal peritoneal metastases(CPM).METHODS:An electronic literature search was carried out to identify publications reporting oncological outcome data(overall survival and/or disease free survival and/or recurrence rates)following CRS and IPC for treatment of CPM.Studies reporting outcomes following CRS and IPC for cancer subtypes other than colorectal were only included if data were reported independently for colorectal cancer-associated cases;in addition studies reporting outcomes for peritoneal carcinomatosis of appendiceal origin were excluded.RESULTS:Twenty seven studies,published between1999 and 2013 with a combined population of 2838patients met the predefined inclusion criteria.Included studies comprised 21 case series,5 case-control studies and 1 randomised controlled trial.Four studies provided comparative oncological outcome data for patients undergoing CRS in combination with IPC vs systemic chemotherapy alone.The primary indication for treatment was CPM in 96%of cases(2714/2838)and recurrent CPM(rCPM)in the remaining 4%(124/2838).In the majority of included studies(20/27)CRS was combined with hyperthermic intraperitoneal chemotherapy(HIPEC).In 3 studies HIPEC was used in combination with early post-operative intraperitoneal chemotherapy(EPIC),and 2 studies used EPIC only,following CRS.Two studies evaluated comparative outcomes with CRS+HIPEC vs CRS+EPIC for treatment of CPM.The delivery of IPC was performed using an'open'or'closed'abdomen approach in the included studies.CONCLUSION:The available evidence presented in this review indicates that enhanced survival times can be achieved for CPM after combined treatment with CRS and IPC. | Reza Mirnezami Brendan J Moran Kate Harvey Tom Cecil Kandiah Chandrakumaran Norman Carr Faheez Mohamed Alexander H Mirnezami | 2014 | World Journal of Gastroenterology2014，20，38： | 6 |
| 2 | Electronic Prescribing and Other Forms of Technology to Reduce Inappropriate Medication Use and Polypharmacy in Older People: A Review of Current Evidence显示文摘 | Barbara Clyne Marie C. Bradley Carmel Hughes Tom Fahey Kate L. Lapane | 2012 | Clinics in Geriatric Medicine2012，，2： | 1 |
| 3 | Cycle analysis of low and high H2 utilization SOFC/gas turbine combined cycle for CO2 recovery显示文摘 | Takuto Araki Takuya Taniuchi Dalsuke Sunakawa Mitsuyuki Nagabama Kazuo Onda Tom Kate | 2007 | Journal of Power Sources2007，171，2007： | 1 |
| 4 | High baseline serum thymidine kinase 1 level predicts unfavorable outcome in patients with follicular lymphoma显示文摘 | Ví t Prochá zka Edgar Faber Lud&ecaron k Raida Kate&rcaron ina Langová Karel Indrá k Tomá &scaron Papají k | 2012 | Leukemia & Lymphoma2012，，： | 1 |
| 5 | Chromium speciation using an automated liquid handling system with inductively coupled plasma-mass spectrometric detection显示文摘 | KATE D M ROB H TOM R | 1999 | Talanta1999，49，5： | 1 |
| 6 | The Effects of combination chemotherapy and highly active antiretroviral therapy on immune parameters in HIV associated lymphoma 显示文摘 | Mark B Tom P Kate F | 2001 | J Clin Oncol2001，20，： | 1 |
| 7 | Redox process of Pd-SnO2 system显示文摘 | KATE(R)INA V MIHAIL M | 2004 | Surface Science2004，，： | 1 |
| 8 | Effect of hydrothermal treatment on properties of Ni–Al layered double hydroxides and related mixed oxides显示文摘 | Franti?ek Kovanda Tomá? Rojka Petr Bezdi?ka Květa Jirátová Lucie Obalová Kate?ina Pacultová Zdeněk Bastl Tomá? Grygar | 2008 | Journal of Solid State Chemistry2008，，1： | 1 |
| 9 | 打击食品浪费:来自世界各地的四个故事(续)显示文摘在全世界,诸如食品分享俱乐部以及旨在为贫穷农民减少收获后损失的项目等活动正在发挥重大影响。 | Kate Lyons Tom Phillips 埃米·法伦 凯特·康诺利 冯雪 | 2015 | 英语文摘2015，0，11： | 0 |
| 10 | 打击食品浪费:来自世界各地的四个故事显示文摘在全世界,诸如食品分享俱乐部以及旨在为贫穷农民减少收获后损失的项目等活动正在发挥重大影响。 | Kate Lyons Tom Phillips Amy Fallon Kate Connolly 冯雪 | 2015 | 英语文摘2015，0，10： | 0 |
| 11 | Methodological challenges of cross-language qualitative research with South Asian communities living in the UK显示文摘Objective:We investigate(1)the influence of ethnic,gender,and age concordance with inter-viewers and(2)how expression of qualitative data varies between interviews delivered in English and community languages(Punjabi/Urdu)with monolingual and bilingual participants across three generations of the Indian Sikh and Pakistani Muslim communities living in the UK.Methods:We analyzed and interpreted semi-structured interview transcripts that were designed to collect data about lifestyles,disease management,community practices/beliefs,and social net-works.First,qualitative content analysis was applied to transcripts.Second,a framework was ap-plied as a guide to identify cross-language illustrations where responses varied in length,expression and depth.Results:Participant responses differed by language and topic.First-generation migrants when discussing religion,culture,or family practice were far likelier to use group or community narra-tives and give a longer response,indicating familiarity with or importance of such issues.Ethnic and gender concordance generated greater rapport between researchers and participants centered on community values and practices.Further,open-ended questions that were less direct were better suited for first-generation migrants.Conclusion:Community-based researchers need more time to complete interviews in second languages,need to acknowledge that narratives can be contextualized in both personal and com-munity views,and reframe questions that may lead to greater expression.Furthermore,we detail a number of recommendations with regard to validating the translation of interviews from commu-nity languages to English as well as measures for testing language proficiency. | Manbinder S.Sidhu Farina Kokab Kate Jolly Tom Marshall Nicola K.Gale Paramjit Gill | 2016 | Family Medicine and Community Health2016，4，2： | 0 |
| 12 | 急性下呼吸道感染的抗生素处方策略及用药说明——随机对照试验显示文摘背景:在初级医疗机构治疗的疾病中,急性下呼吸道感染最为常见。尽管有关抗生素应用的系统综述很少,且得出的结论各有不同,但仍有许多内科医生开处抗生素。
目的:评价急性下呼吸道感染的三种抗生素处方策略和一种用药说明的有效性。设计、地点及患者:于1998年8月18日至2003年7月30日进行随机对照试验,807例病人均因单纯急性下呼吸道感染而于初级保健机构就诊。按析因设计将病人分为6组:有用药说明书或无用药说明书与3个不同抗生素使用组(立即使用抗生素、不使用抗生素、延后使用抗生素)的任一组合。
干预:三种处方策略包括立即使用抗生素(n=262)、延后使用抗生素(n=272)与不使用抗生素(n=273)。每组大约一半病人给予用药说明书(立即使用抗生素组129例,延后使用抗生素组136例,不使用抗生素组140例)。
主要观测指标:症状持续时间及严重程度。
结果:总共562例(70%)病人交回了完整的日记,78例(10%)病人提供了症状持续时间及严重程度的信息。分级至少为“一个小问题”的咳嗽平均持续11.7天(25%的病人咳嗽持续≥17天)。用药说明书对主要结果没有影响。与不使用抗生素组相比,其他策略并未使咳嗽持续时间(延后使用抗生素组:0.75天;95%可信区间[CI],-0.37~1.88;立即使用抗生素组:0.11天;95%CI,-1.01~1.24)或其他主要结局发生改变。与立即使用抗生素组相比,延后使用抗生素组和对照组较少使用抗生素(分别为96%、20%和16%,P〈0.001),少数病人感到非常满意(分别为86%、77%和72%,P=0.005),少数病人相信抗生素的效果(分别是75%、40%和47%,P〈0.001)。使用抗生素组的病人1个月内复诊者较少(不使用抗生素组、延后使用抗生素组和立即使用抗生素组分别为0.19、0.12和0.11,P=0.04);有用药说明书的病人就诊较多(无用药说明书和有用药说明书者分别为0.11和0.17,P=0.02)。
结论:单纯急性下呼吸道感染者不用抗生素或延后使用抗生素是可以接受的,症状的消失在各组间差别很小,应明显减少抗生素的使用,消除对抗生素效果的迷信。 | Paul Little Kate Rumsby Joanne Kelly Louise Watson Michael Moore Gregory Warner Tom Fahey Lan Williamson 马凌云(译) 文仲光(校) | 2006 | 美国医学会杂志(中文版)2006，25，4： | 0 |
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