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您的检索式：作者名="Tran Dieu Linh"
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| 1 | Injectable reactive oxygen and nitrogen species-controlling hydrogels for tissue regeneration:current status and future perspectives显示文摘The dual role of reactive oxygen and nitrogen species(RONS)in physiological and pathological processes in biological systems has been widely reported.It has been recently suggested that the regulation of RONS levels under physiological and pathological conditions is a potential therapy to promote health and treat diseases,respectively.Injectable hydrogels have been emerging as promising biomaterials for RONS-related biomedical applications owing to their excellent biocompatibility,three-dimensional and extracellular matrix-mimicking structures,tunable properties and easy functionalization.These hydrogels have been developed as advanced injectable platforms for locally generating or scavenging RONS,depending on the specific conditions of the target disease.In this review article,the design principles and mechanism by which RONS are generated/scavenged from hydrogels are outlined alongside a discussion of their in vitro and in vivo evaluations.Additionally,we highlight the advantages and recent developments of these injectable RONS-controlling hydrogels for regenerativemedicines and tissue engineering applications. | Phuong Le Thi Dieu Linh Tran Thai Thanh Hoang Thi Yunki Lee Ki Dong Park | 2022 | Regenerative Biomaterials2022，9，1： | 0 |
| 2 | Lexical Collocations of “EAT” and “WEAR” in American English from 1800 to 2000:A Corpus-Based Study of Sociolinguistics Approach显示文摘Collocations transmit cultural and societal meanings and stereotypes which have built up over time;therefore,research of collocations,especially lexical collocations,provides particular insights into history.The present study examines verb-noun lexical collocations of'eat'and'wear'between 1800 and 2000 through three corpora:Corpus of Historical American English(COHA),Corpus of Contemporary American English(COCA)and Google Books(American).Whilst exploring possible semantic changes in the use of these two verbs,the author seeks for the explanation of the alternative of old collocations and the appearance of new ones.It is found that there is not much fluctuation in the meaning of'eat'and'wear'after two centuries.Besides,it also reveals that social changes have had great impacts on language changes which can modify or create new collocations in the verbnoun lexical collocation of'eat'and 'wear'.By means of identifying the syntagmatic and paradigmatic properties of verb-noun lexical collocation of'eat'and 'wear',it is clearly shown that corpus has potential applications in translation studies,language teaching,and other scientific fields. | Tran Dieu Linh Nguyen Thi Thu Thuy | 2017 | 外语教育2017，，1： | 0 |
| 3 | Novel enzymatically crosslinked chitosan hydrogels with free-radical-scavenging property and promoted cellular behaviors under hyperglycemia显示文摘The impairment of regenerative processes induced by high blood-glucose level(hyperglycemia) and excessive reactive oxygen species(ROS) contributes to the diabetic complication progression and development. In this study, an injectable, in situ crosslinkable chitosan hydrogel with ROS-scavenging capability was developed by conjugating gallic acid onto the chitosan backbone(CGA). We hypothesized that gallic acid serves as both antioxidant and crosslinking moieties to form hydrogel in situ by means of enzymatic crosslinking with horseradish peroxidase(HRP). The rapid gelation(from 30 s) was observed by vial tilting. The mechanical properties and microstructures of CGA hydrogels can be well controlled by varying the concentrations of H_2 O_2. The ROSscavenging ability of these CGA hydrogels was demonstrated against DPPH radical, hydroxyl radical, and total reducing power. Notably, in an in vitro hyperglycemia environment, CGA hydrogels significantly improved the proliferation and migration of human dermal fibroblast cells, which are closely related to diabetic wound healing. These results suggest that CGA hydrogels have potential as advanced materials for the treatment of diabetes-related diseases via attenuating the excessive ROS production and improving cellular behaviors. | Dieu Linh Tran Phuong Le Thi Thai Thanh Hoang Thi Ki Dong Park | 2020 | Progress in Natural Science:Materials International2020，30，5： | 0 |
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