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| 1 | Stem cell application for osteoarthritis in the knee joint: A minireview显示文摘Knee osteoarthritis is a chronic, indolent disease that will affect an ever increasing number of patients, especially the elderly and the obese. It is characterized by degeneration of the cartilage substance inside the knee which leads to pain, stiffness and tenderness. By some estimations in 2030, only in the United States, this medical condition will burden 67 million people. While conventional treatments like physiotherapy or drugs offer temporary relief of clinical symptoms, restoration of normal cartilage function has been difficult to achieve. Moreover, in severe cases of knee osteoarthritis total knee replacement may be required. Total knee replacements come together with high effort and costs and are not always successful. The aim of this review is to outline the latest advances in stem cell therapy for knee osteoarthritis as well as highlight some of the advantages of stem cell therapy over traditional approaches aimed at restoration of cartilage function in the knee. In addition to the latest advances in the field, challenges associated with stem cell therapy regarding knee cartilage regeneration and chondrogenesis in vitro and in vivo are also outlined and analyzed. Furthermore, based on their critical assessment of the present academic literature the authors of this review share their vision about the future of stem cell applications in the treatment of knee osteoarthritis. | Kristin Uth Dimitar Trifonov | 2014 | World Journal of Stem Cells2014,6,5: | 6 |
| 2 | Growth of carbon nanotube arrays on various CtxMey alloy films by chemical vapour deposition method显示文摘Carbon nanotube(CNT) arrays were fabricated on Ct-Me-N-(O) alloys with content of Ct in the range of 6–40 at.% by chemical vapour deposition. The Ct was a catalytic metal from the group of the following elements: Ni, Co, Fe, Pd, while Me was a transition metal from the group of Ⅳ–Ⅶ of the periodic table(where Me = Ti, V, Cr, Zr, Nb, Mo, Ta, W, Re). Carbon nanotubes were found to grow efficiently on the alloy surface with its composition containing Ti, V, Cr, Zr, Hf, Nb or Ta. The growth of CNTs was not observed when the alloy contained W or Re. Additions of oxygen and nitrogen in the alloy facilitated the formation of oxynitrides and catalyst extrusion on the alloy surface. Replacement of the metals in alloy composition affected the diameter of the resulting CNTs. The obtained results showed that the alloy films of varying thickness(10–500 nm) may be used for the CNTs growth. The resulting CNT material was highly homogenous and its synthesis reproducible. | Pawel Mierczynski Sergey V.Dubkov Sergey V.Bulyarskii Alexander A.Pavlov Sergey N.Skorik Alexey Yu Trifonov Agnieszka Mierczynska Eugene P.Kitsyuk Sergey A.Gavrilov Tomasz P.Maniecki Dmitry G.Gromov | 2018 | Journal of Materials Science & Technology2018,34,3: | 2 |
| 3 | Cell surface engineering with polyelectrolyte-stabilized magnetic nanoparticles: A facile approach for fabrication of artificial multicellular tissue-mimicking clusters显示文摘再生药要求新方法为像织物的构造的制造装配并且操作房间。这里,我们用稳定聚合物的磁性的 nanoparticles (MNP ) 为人的房间的房间表面工程报导一条新奇途径。Cationic 聚合电解质涂的 MNP 直接被扔到细胞的膜上,生产 mesoporous 半渗透的层和显示的房间有磁力地应答。MNP 的免职能在分钟以内被完成,在房间友好的条件(房间温度和生理的媒介) 下面。显微镜学(TEM, SEM, AFM,和提高的黑暗地的成像) 揭示了 nanoparticles 的置闰进细胞的 microvilli 网络。详细生存能力调查被执行并且建议 MNP 不禁止膜正直,酶的活动,粘附,增长,或细胞骨架形成,并且不在癌症或主要房间导致 apoptosis。最后,有磁力地, functionalized 房间被采用制作可行分层平面(二房间的层) 房间表和 3D 多细胞的球状体。 | Maria R. Dzamukova Ekaterina A. Naumenko Elvira V. Rozhina Alexander A. Trifonov Rawil F. Fakhrullin | 2015 | Nano Research2015,8,8: | 2 |
| 4 | The origin of the recent swine influenza A (HIN1) viru sinfecting humans显示文摘 | Trifonov V Khiabanian H Greenbaum B | 2009 | Eur Surveill2009,14,19: | 1 |
| 5 | Nonclonability correlates with genomic instability:a case study of a unique DNA region显示文摘 | Razin S V Ioudinkova E S Trifonov E N | 2001 | Mol Biol2001,307,2: | 1 |
| 6 | Geology and mineralization of the Uchkoshkon tin deposit associated with a breccia pipe, Eastern Kyrgyzstan显示文摘 | L.I. Solomovich B.A. Trifonov S.E. Sabelnikov | 2011 | Ore Geology Reviews2011,,: | 1 |
| 7 | Early detection of G+C differences in bacterial species inferred from the comparative analysis of the two completely sequenced Helicobacter pylori strains显示文摘 | Bellgard M Schibeci D Trifonov E | 2001 | J Mol Evol2001,53,45: | 1 |
| 8 | Analysis of the coding genome of diffuse large B-cell lymphoma显示文摘 | Pasqualucci L Trifonov V Fabbri G | 2011 | Nat Genet2011,43,9: | 1 |
| 9 | Recent geodynamics of major strike-slip zones显示文摘The subject of this study is strike-slip fault zones,where temporal variations of accumulation in strike-slip deformation complicate the standard process of deformation accumulation and release during strong earthquakes.These temporal variations are expressed in the El Ghab segment of the Dead Sea Transform zone(DST,Eastern Mediterranean)and in the Talas-Fergana fault zone(Central Asia).According to Global Positioning System(GPS)data,the strike-slip deformations within these zones are not now accumulating or are accumulating at a rate that is significantly less than their average rate during the Holocene and Quaternary or the Pliocene-Quaternary.Simultaneously,weak transverse shortening has been measured in both zones by GPS.In both of these zones,strong earthquakes have not registered within the XX century,yet epochs of intensified seismicity(strong earthquakes)took place throughout history.In the southern and central parts of the El Ghab zone,there is evidence of 30 strong historical earthquakes of Ms≥5.7;however,no instrumental earthquakes of Ms≥5 have been identified.The temporal distribution of seismic energy released by these earthquakes demonstrates a 350±50-year cycle.Values for the seismic energies released during the peak phases of these cycles are approximated by a sinusoid that suggests the possibility of a≥1800-year cycle('hyper-cycle'),which began around the 3rd century,reached its maximum in the 12th century,and has continued until now.A combination of geological,archaeoseismological,and geodetic data show that the rate of sinistral strike-slip deformation varied in the fault zone,probably in conformity with the variation of seismicity during the'hyper-cycle.'In the Talas-Fergana fault zone,trenching and^(14)C dating that was correlated with right lateral offsets,gave a possible preliminary estimate of the average rates of the Late Holocene strike slip of about10 mm per year,with a decrease in the SE direction to 4 mm-4.5 mm per year.These studies also showed that the slip in the Talas-Fergana fault zone was realized mainly during strong earthquakes.New trenching and^(14)C dating of paleoearthquake records identified the epoch of seismicity intensification dating to theⅩⅣ-ⅩⅦcenturies.These paleoearthquakes could produce a total dextral slip at several meters.Therefore,consideration of these epochs was necessary to determine a calculated average slip rate during the Late Holocene.The main shock and the strongest aftershocks of the Altai earthquake of September 27,2003,with Ms=7.0 demonstrated a strike-slip focal mechanism with an NW-trendingplane of the right lateral slip.An approximately 65 km-long NW-trending seismic rupture with a right lateral slip of up to 2 m,formed during the earthquake.The aftershock activity significantly decreased in 2004—2005 when reverse and rarer normal focal mechanisms became dominant.In the Palmyrides and the southern Aleppo block(NW Syria),strong earthquakes in 1994(Mw=5.3)and 1996(Mw=5.5)had strike-slip focal mechanisms,while only weak(magnitudes 1.1 to 3.3)earthquakes occurred in 2009-2011;the overwhelming majority of these weak earthquakes had normal and reverse mechanisms.In all of the cases mentioned above,strike-slip deformation was expressed only or mainly during strong earthquakes.At other times,the rate of its accumulation was small and the dominant stress conditions led to transverse shortening,rarely resulting in local lengthening of the tectonic zone.These variations are caused by the tectonic peculiarities of these zones.The sinistral component of the deformation is related to the shift of the Arabian Plate relative to the African one,but also the transverse component is related to the continental slope and is expressed by the Coastal range shortening that exists in the El Ghab segment zone.There is not only a dextral deformation component,but also a transverse component,expressed by shortening of the Fergana and Talas ranges existing in the Talas-Fergana fault zone.In both zones,the shortening component became appreciable or dominant when the strike-slip deformation rate decreased.Similar,but more local,relationships were expressed in the epicentral area of the 2003 Altai earthquake and in the Western Palmyrides. | Trifonov Vladimir G. Korzhenkov Andrey M. Omar Khaled M. | 2015 | Geodesy and Geodynamics2015,6,5: | 1 |
| 10 | Analytical and Numerical Studies of Wire-mesh Metallic Photonic Crystals显示文摘 | TRIFONOV T MARSAL L F RODRIGUEZ A | 2004 | Phys Rev B2004,70,19: | 1 |
| 11 | The origin of the recent swine influenza A ( H1N 1 ) virus infecling humans 显示文摘 | Trifonov V Khiabanian H Greenbaum B | 2009 | Euro Surveill2009,14,19: | 1 |
| 12 | Flooding in two-phase counter-current flows :Numerical investigation of the gas-liquid wavy interface usingthe Navier-Stokes equations 显示文摘 | Trifonov Y | 2010 | International Journal ofMultiphase Flow2010,36,7: | 1 |
| 13 | A computer algorithm for testingpotential prokaryotic terminators显示文摘 | BRENDEL V TRIFONOV E | 1984 | Nucleic Acids Research1984,12,10: | 1 |
| 14 | A theoretical study of the 1,2,3-triazole-imino-diazomethane isomerism in the gas phase显示文摘 | Trifonov R E Rostislav E | | 0,,01: | 1 |
| 15 | The origin of the recent swine influenza A (H1N1 ) virus infecting humans 显示文摘 | Trifonov V K hiabanian H Greenbavm B | 2009 | Euro Surveil2009,14,19: | 1 |
| 16 | Terminators of tran-scription with RNA polymerase from Escherichia coli:whatthey look like and how to find them显示文摘 | BRENDEL V HAMM G TRIFONOV E | 1986 | Journal of BiomolecularStructure&Dynamics1986,3,4: | 1 |
| 17 | The origin of the recent swine influenza A(H1N1)virus infectinghumans显示文摘 | Trifonov V Khiabanian H Greenbaum B Rabadan R | 2009 | Euro Surveill2009,14,19: | 1 |
| 18 | Postcollisional granites in the South Tien Shah Variscan collisional belt, Kyrgyzstan显示文摘 | Solomovich L I Trifonov B A | 2002 | Journal of Asian Earth Sciences2002,21,: | 1 |
| 19 | Diagnostic value of heart type fatty-acid binding protein in early hospitalized patients with non-ST elevation acute coronary syndrome显示文摘 | Trifonov IR Katrukha AG Iavelov IS | 2003 | Kardiologiia2003,43,: | 1 |
| 20 | A theoretical study of the 1,2,3-triazole-imino-diazomethane isomerism in the gas phase显示文摘 | TRIFONOV R E ROSTISLAV E | 2000 | Heterocycles2000,52,1: | 1 |