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| 1 | High-fidelity multimode fibre-based endoscopy for deep brain in vivo imaging显示文摘Progress in neuroscience relies on new techniques for investigating the complex dynamics of neuronal networks.An ongoing challenge is to achieve minimally invasive and high-resolution observations of neuronal activity in vivo inside deep brain areas.Recently introduced methods for holographic control of light propagation in complex media enable the use of a hair-thin multimode optical fibre as an ultranarrow imaging tool.Compared to endoscopes based on graded-index lenses or fibre bundles,this new approach offers a footprint reduction exceeding an order of magnitude,combined with a significant enhancement in resolution.We designed a compact and high-speed system for fluorescent imaging at the tip of a fibre,achieving a resolution of 1.18±0.04μm across a 50-μm field of view,yielding 7-kilopixel images at a rate of 3.5 frames/s.Furthermore,we demonstrate in vivo observations of cell bodies and processes of inhibitory neurons within deep layers of the visual cortex and hippocampus of anaesthetised mice.This study paves the way for modern microscopy to be applied deep inside tissues of living animal models while exerting a minimal impact on their structural and functional properties. | Sergey Turtaev Ivo T.Leite Tristan Altwegg-Boussac Janelle M.P.Pakan Nathalie L.Rochefort Tomáš Čižmár | 2018 | Light(Science & Applications)2018，7，1： | 8 |
| 2 | Pentanucleotide repeat length polymorphism at the human CD4 locus显示文摘 | EDWARDS M C CLEMENS P R TRISTAN M | 1991 | Nucleic Acids Research1991，19，17： | 1 |
| 3 | Estimating profitability of two biochar production scenarios:slow pyrolysis vs fast pyrolysis显示文摘 | Tristan R Brown Mark M Wright Robert C Brown | | 0，，： | 1 |
| 4 | Clinical significance of prostate 18F-labelled fluorodeoxyglucose uptake on positron emission tomography/computed tomography:A five-year review显示文摘AIM To determine the significance and need for investigation of incidental prostatic uptake in men undergoing ^(18)F-labelled fluorodeoxyglucose(^(18)F-FDG) positron emission tomography/computed tomography(PET/CT) for other indications.METHODS Hospital databases were searched over a 5-year period for patients undergoing both PET/CT and prostate magnetic resonance imaging(MRI). For the initial analysis, the prostate was divided into six sectors and suspicious or malignant sectors were identified using MRI and histopathology reports respectively. Maximum and mean ^(18)F-FDG standardised uptake values were measured in each sector by an investigator blinded to the MRI and histopathology findings. Two agematched controls were selected per case. Results were analysed using a paired t-test and one-way ANOVA. For the second analysis, PET/CT reports were searched for prostatic uptake reported incidentally and these patients were followed up. RESULTS Over a 5-year period, 15 patients underwent both PET/CT and MRI and had biopsy-proven prostate cancer.Malignant prostatic sectors had a trend to higher ^(18)F-FDG uptake than benign sectors, however this was neither clinically nor statistically significant(3.13 ±0.58 vs 2.86 ± 0.68, P > 0.05). ^(18)F-FDG uptake showed no correlation with the presence or histopathological grade of tumour. ^(18)F-FDG uptake in cases with prostate cancer was comparable to that from age-matched controls. Forty-six(1.6%) of 2846 PET/CTs over a 5-year period reported incidental prostatic uptake. Of these, 18(0.6%) were investigated by PSA, 9(0.3%)were referred to urology, with 3(0.1%) undergoing MRI and/or biopsy. No cases of prostate cancer were diagnosed in patients with incidental ^(18)F-FDG uptake in our institute over a 5-year period.CONCLUSION ^(18)F-FDG uptake overlaps significantly between malignant and benign prostatic conditions. Subsequent patient management was not affected by the reporting of incidental focal prostatic uptake in this cohort. | Madhurima R Chetan Tristan Barrett Ferdia A Gallagher | 2017 | World Journal of Radiology2017，9，9： | 1 |
| 5 | Interannual variability of hu- man Plague occurrence in the western united states explained by tropical and North Pacific ocean climate variability 显示文摘 | Ari TB Gershunov A Tristan R | 2010 | Am J Trop Med Hyg2010，83，3： | 1 |
| 6 | A review of cellulosic biofuel commercial- scale projects in the united states显示文摘 | Tristan R Robert C | 2013 | Biofuels Bioproducts and Biorefining2013，7，3： | 1 |
| 7 | Herpesvirus infection in European flat oysters Ostrea edulis obtained from brood stocks of various geographic origins and grown in Galicia (NW Spain) 显示文摘 | Da Silva P Tristan R Fuentes J | 2008 | Diseases of Aquatic Organisms2008，78，3： | 1 |
| 8 | A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing显示文摘 | Pierce C G Uppuluri P Tristan A R | 2008 | Nat Protoc2008，3，9： | 1 |
| 9 | Virtual network computing显示文摘 | Tristan Richardson Quentin Stafford-Fraser Kenneth R Wood | 1998 | IEEE Internet Computing1998，2，1： | 1 |
| 10 | Procalcitonin and C-reac- tive protein in hospitalized adult patients with community-acquired pneumonia or exacerbation of asthma or COPD 显示文摘 | Mona B Tristan W C Carlene R | 2011 | Chest2011，139，6： | 1 |
| 11 | An 8 b, 40 M samples/s switched-current-mode track-and-hold circuit on a BiCMOS sea-of-gates array 显示文摘 | TRISTAN R FRANCOIS K MICHEL J D | 1996 | IEEE J of SSC1996，31，3： | 1 |
| 12 | Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study显示文摘 | Martin J Elliott Paolo De Coppi Simone Speggiorin Derek Roebuck Colin R Butler Edward Samuel Claire Crowley Clare McLaren Anja Fierens David Vondrys Lesley Cochrane Christopher Jephson Samuel Janes Nicholas J Beaumont Tristan Cogan Augustinus Bader Alexan | 2012 | The Lancet2012，，9846： | 1 |
| 13 | An 8-b, 40 M samples/s switched-current-mode track-and-hold cir-cuit on a BiCMOS sea-of-gates array显示文摘 | Tristan R Francois K Michel J D | 1996 | IEEE J of Solid-state Circuits1996，31，3： | 1 |
| 14 | PVPP-polyphenol complexes:A mole-cular approach显示文摘 | BENEDICTE L VIRGINIE M L TRISTAN R | 2006 | Journal of agricultural and food chemistry2006，54，12： | 1 |
| 15 | Magnetization and specific heat of TbFe3(BO3)4:Experiment and crystal-field calculations显示文摘 | Popova E A Volkov D V Vasiliev A N Demidov A A Kolmakova N P Gudim I A Bezmatemykh L N Tristan N Skourski Yu Büchner B Hess C Klingeler R | | 0，，22： | 1 |
| 16 | A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal suscepti- bility testing显示文摘 | Pierce C G Uppuluri P Tristan A R | 2008 | Nat Protoe2008，3，9： | 1 |
| 17 | Liposome retention in size exclusion chromatography显示文摘 | Tristan R Audrey M Jean-Luc D | 2005 | BMC Biotechnology2005，5，11： | 1 |
| 18 | The signal peptide of Staphylococcus aureus panton valentine leukocidin LukS compo- nent mediates increased adhesion to heparan sulfates显示文摘 | Tristan A Benito Y Montserret R | 2009 | PLoS One2009，4，4： | 1 |
| 19 | An 8-b, 40 M samples/s switched-current-mode track-and-hold circuit on a BiCMOS sea-of-gates array 显示文摘 | TRISTAN R FRANCOIS K MICHEL J D | 1996 | IEEE J of Solid-Slate Circuits1996，31，3： | 1 |
| 20 | The signal peptide of Staphylococcus aureus panton-valentine leukocidin LukS component mediates increased adhesion to heparan sulfates显示文摘 | TRISTAN T A BENITO T MONTSERRET R | 2009 | PLoS ONE2009，4，4： | 1 |
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