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12篇 您的检索式:作者名="Tschida"
    题名 作者 年代 出处 被引量
1Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia.Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng 2015World Journal of Gastroenterology2015,21,42:2
2Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the Sleeping Beauty transposon system显示文摘Keng V W Tschida B R Bell J B 2011Hepatology2011,53,3:1
3Esmolol hydrochloride:An ultrashort-acting,beta-adrenergic blocking agent显示文摘Angaran D M Schultz N J Tschida V H 1986Clin Pharnracol1986,5,4:1
4Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the sleeping Beauty transpose on system显示文摘Keng VW Tschida BR Bell JB 2011Hepatol2011,53,3:1
5Rapid spine stabilization and synaptic enhancement at the onset of behavioural learning 显示文摘ROBERTS T F TSCHIDA K A MOONEY R 2010Nature2010,463,7283:1
6Deafening drives Cell- Type-Specific changes to dendritic spines in a sensorimo- tor nucleus important to learned vocalizations 显示文摘TSCHIDA K A MOONEY R 2012Neu- ron2012,73,:1
7A retrospective study of sodium nitroprusside use and assessment of the potential risk of cyanide poisoning显示文摘JOHANNING R J ZASKE D E TSCHIDA S J 1995Pharmacotherapy1995,15,6:1
8The role of auditory feedback in vocal learning and maintenance显示文摘Katherine Tschida Richard Mooney 2011Current Opinion in Neurobiology2011,,2:1
9Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR显示文摘Vincent W. Keng Daniela Sia Aaron L. Sarver Barbara R. Tschida Danhua Fan Clara Alsinet Manel Solé Wai L. Lee Timothy P. Kuka Branden S. Moriarity Augusto Villanueva Adam J. Dupuy Jesse D. Riordan Jason B. Bell Kevin A. T.Silverstein Josep M. Llovet David 2012Hepatology2012,,1:1
10A retrospective study of sodium nitroprusside use and assessment of cyanide poisoning显示文摘Johanning RJ Zaske DE Tschida SJ 1995Pharmacotherapy1995,15,6:1
11Auditory synapses to song premotor neurons are gated off during vocalization in zebra finches显示文摘HAMAGUCHI K TSCHIDA K A YOON I 2014Elife Sciences2014,3,4:1
12The role of auditory feedback in vocal learning and maintenance显示文摘Katherine Tschida Richard Mooney 2011Current Opinion in Neurobiology2011,,2:1
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