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| 1 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 2 | Phycobilin : cystein-84 biliprotein lyase,a near universal lyase for cysteine-84-binding sites in cyanobacterial phycobiliproteins 显示文摘 | Zhao K H Su P Tu J M | 2007 | Proc Natl Acad Sci USA2007，104，14： | 1 |
| 3 | Nighttime transpiration in woody plants from contrasting ecosystems 显示文摘 | DAWSON T E BURGESS S S O TU K P | 2007 | Tree Physiology2007，27，： | 1 |
| 4 | Numerical simulation of micro-bubble drag reductionusing population balance model显示文摘 | MOHANARANGAM K CHEUNG S C P TU J Y etal | 2009 | Ocean Engineering2009，36，： | 1 |
| 5 | Genome, transcriptome, and secretome analysis of wood decay fungus Postia placenta supports unique mechanisms of lignocellulose conversion 显示文摘 | Martinez D Challacombe J Morgenstern 1 Hibbett D Schmoll M Kubicek CP Ferreira P Ruiz-Duenas FJ Martinez AT Kersten P Hammel KE Wymelenberg AV Gaskell J Lindquist E Sabat G BonDurant SS Larrondo LF Canessa P Vicuna R Yadav J Doddapaneni H Subramanian V Pisabarro AG Lavin JL Oguiza JA Master E Henrissat B Coutinho PM Harris P Magnuson JK Baker SE Bruno K Kenealy W Hoegger PJ Kties U Ramaiya P kucas S Salamov A Shapiro H Tu H Chee CL Misra M Xie G Teter S Yaver D James T Mokrejs M Pospisek M Grigoriev IV Brettin T Rokhsar D Berka R Cullen D | 2009 | PNAS2009，106，6： | 1 |
| 6 | Effect of intermetallic compounds on the thermal fatigue of surface mount solder joints显示文摘 | Tu P L Chan Y C Lai J K L | 1997 | IEEE Transactions on Components Packaging and Manufacturing Technology Part B: Advanced Packaging1997，20，1： | 1 |
| 7 | Photooxidation of olefins under oxygen in platinum(II) complex-loaded mesoporous mole- cular sieves 显示文摘 | Feng K Zhang R Y Wu L Z Tu B Peng M L Zhang L P Zhao D Y Tung C H | 2006 | Journal of the American Chemical Society2006，128，14： | 1 |
| 8 | Biochemical basis of oxidative protein folding in the endoplasmic reticulum 显示文摘 | Tu B P Ho-Schleyer S C Travers K J | 2000 | Science2000，290，24： | 1 |
| 9 | Development of HS-RT-LAMP (loop-mediated isothermal amplification) system for rapid diagnosis of H5 avian influenza virus infection 显示文摘 | Imai M Ninomiya A Minekawa H Notomi T Ishizaki T Tu P V Tien N T K Tashiro M and Odagiri T | 2006 | Journal of Virological Methods2006，24，44： | 1 |
| 10 | Inferior vena cava syndrome following percutaneous vertebroplasty with polymethylmethacrylate 显示文摘 | Kao F C Tu Y K Lai P L | 2008 | Spine2008，33，10： | 1 |
| 11 | Phycobilin : cystein-84 biliprotein lyase, a near-universal lyase for cysteine-84-binding sites in cyanobacterial phycobiliproteins lyase for cysteine-84-binding sites in cyanobacterial phycobiliproteins 显示文摘 | Zhao K H Su P Tu J M Wang X Liu H Ploscher M Eichacker L Yang B Zhou M Scheer H | 2007 | PNAS2007，104，14： | 1 |
| 12 | Solder reaction-assisted crystallization of electroless Ni-P under bump metallization in low cost flip chip technology显示文摘 | JANG J W KIM P G TU K N FREAR D R THOMPSON P | 1999 | Journal of Applied Physics1999，85，： | 1 |
| 13 | Evaluation of 5kW Proton Exchange Membrane Fuel Cell Stack Operatedat 95°C under Ambient Pressure 显示文摘 | Tu Z K Zhang H N Luo Z P | 2013 | Journal of PowerSources2013，222，15： | 1 |
| 14 | Global estimates of the land–atmosphere water flux based on monthly AVHRR and ISLSCP-Ⅱdata,validated at16 FLUXNET sites显示文摘 | Fisher J B Tu K P Baldocchi D D | 2008 | Remote Sensing of Environment2008，112，3： | 1 |
| 15 | Effect of intermetallic compounds on the shear fatigue of Cu/63Sn37Pb solder joint 显示文摘 | Chan Y C Tu P L So A C K | 1997 | Components Packaging and Manufacturing Technology1997，20，4： | 1 |
| 16 | Use of laser-scattering imaging to study tomato-fruit quality in relation to acoustic and compression measurements显示文摘 | Tu K Janesok P Nicolai B | 2000 | International Journal of Food Science and Technology2000，35，50： | 1 |
| 17 | Synthesis and frictional properties of array film of amorphous carbon nanofibers on anodic aluminum oxide显示文摘 | TU J P ZHU L P HOU K | 2003 | Carbon2003，41，： | 1 |
| 18 | Particle Size Effects of Carbon Sources on Electrochemical Properties of LiFePO4/C Composites 显示文摘 | FEY G T TU H J HUANG K P | 2012 | Journal of Solid State Elec- trochemistry2012，16，5： | 1 |
| 19 | Brain anatomical structure segmentation by hybrid discriminative/genera- tive models 显示文摘 | TU Z NARR K L DOLLAR P | 2008 | IEEE Transaction on Medical Imaging2008，27，4： | 1 |
| 20 | Effects of carbon nanotubes on the high-rate discharge properties of nickel/metal hydroxide batteries 显示文摘 | Lv J Tu J P Zhang W K Wu J B Wu H M Zhang B | 2004 | Journal of Power Sources2004，132，： | 1 |
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