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| 1 | 影响慢性阻塞性肺病急性加重患者生活质量的危险因素显示文摘目的测定和评价慢性阻塞性肺病(COPD)急性加重患者的生活质量和潜在危险因素的发生率及其影响。方法研究两家大型医院因COPD急性加重入院的196个中重度COPD患者。在患者出院时和出院后1月稳定状态,测量肺功能指标、精神状态及用圣乔治呼吸问卷测定生活质量,并收集了患者的临床性状、社会性状和照料因素。结果196例患者中,吸烟、抑郁及嗜用镇痛剂、安眠药相当普遍,而完成肺康复、接种流感病毒疫苗和肺炎球菌疫苗以及看护支持却很少。生活质量的症状域均值为55.9,活动域均值为65,影响域均值为32.9,总体均值为46.5。多变量分析显示慢性黏液高分泌症、男性、抑郁、前1年多次入院和治疗依顺性差与症状域值低下独立显著相关;前1年多次入院、抑郁、严重气促和72岁以上老年与活动域值低下独立显著相关;抑郁、前1年多次入院、严重气促、病程长和重度吸烟与影响域值低下独立显著相关;抑郁、前1年多次入院、严重气促和病程长与总体数值低下独立显著相关(P<0.05)。结论COPD急性加重患者的生活质量低下与COPD严重程度、患者精神抑郁状态及照料这些可改善因素有关。 | 曹振英 Tan Wan Cheng Ng Tze Pin | 2005 | 上海第二医科大学学报2005，25，7： | 10 |
| 2 | Molecular changes in hepatic metabolism and transport incirrhosis and their functional importance显示文摘Liver cirrhosis is the common endpoint of many hepatic diseases and represents a relevant risk for liver failure and hepatocellular carcinoma.The progress of liver fibrosis and cirrhosis is accompanied by deteriorating liver function.This review summarizes the regulatory and functional changes in phase Ⅰ and phaseⅡmetabolic enzymes as well as transport proteins and provides an overview regarding lipid and glucose metabolism in cirrhotic patients.Interestingly,phase Ⅰ enzymes are generally down regulated transcriptionally,while phaseⅡenzymes are mostly preserved transcriptionally but are reduced in their function.Transport proteins are regulated in a specific way that resembles the molecular changes observed in obstructive cholestasis.Lipid and glucose metabolism are characterized by insulin resistance and catabolism,leading to the disturbance of energy expenditure and wasting.Possible non-invasive tests,especially breath tests,for components of liver metabolism are discussed.The heterogeneity and complexity of changes in hepatic metabolism complicate the assessment of liver function in individual patients.Additionally,studies in humans are rare,and species differences preclude the transferability of data from rodents to humans.In clinical practice,some established global scores or criteria form the basis for the functional evaluation of patients with liver cirrhosis,but difficult treatment decisions such as selection for transplantation or resection require further research regarding the application of existing non-invasive tests and the development of more specific tests. | Christoph G Dietrich Oliver Götze Andreas Geier | 2016 | World Journal of Gastroenterology2016，22，1： | 10 |
| 3 | Outcome of 1355 consecutive transabdominal chorionic villus samplings in 1351 patients显示文摘Background The true risk of choronic villus sampling (C VS) is poorly defined. The objective of this study was to review the clinical o utcome of transabdominal CVS performed in a university teaching unit, with an em phasis on the complication rate. Methods A comprehensive audit database was maintained for 1351 pregnant women, including 17 sets of twin pregnancies, who had a CVS. Details a nd outcome of all CVSs made in the unit between May 1996 and May 2004 were revie wed. All CVSs were performed by one of 5 operators using the identical techniqu es. Results All procedures were performed transabdominally. A tota l of 1355 CVSs were performed because there were 4 dichorionic twin pregnancies which required 2 punctures. The mean gestation at CVS was (11.8±0.7) weeks, and 97.3% of the procedures were performed between 11 and 13 completed weeks. The majority (96.2%) required only 1 puncture to achieve correct needle placeme nt. The procedure failed to obtain an adequate sample in 4 subjects (0.30%). A total of 1351 chromosomal studies were requested and there was 1 case (0.07%) of culture failure. The results of chromosomal studies were available within 1 4 days in 36.7% of the cases and within 21 days in 94.0%. Overall, 77 chromos omal abnormalities (5.7%) and 5 cases of thalassemia major were detected. Preg nancy outcome was unknown in only 13 singleton subjects (0.96%). In the remain ing 1355 fetuses, there were 76 pregnancy terminations (5.56%), 10 fetal losses with obvious obstetric causes (0.73%), and 21 potentially procedure-relat ed fetal losses (1.54%). In the last group, the majority had one or more co-e xisting obstetric complications. The background fetal loss rate for pregnancies at similar gestational age in the unit was about 0.8%. Therefore, the procedu re-related fetal loss rate was estimated to be at the maximum of 0.74%. Conclusions In experienced hands, first trimester transabdomina l CVS is an accurate and safe invasive prenatal diagnostic procedure. It should be one of the treatment options available to pregnant women who require prenata l genetic diagnosis. | LAU Tze Kin LEUNG Tak Yeung FUNG Tak Yuen Daljit S SAHOTA LEUNG Tse Ngong | 2005 | Chinese Medical Journal2005，，20： | 8 |
| 4 | 电弧喷涂高性能防腐耐磨涂层显示文摘垃圾焚烧厂工件表面通常暴露在含HCl/KCl的高温气氛中,这些高腐蚀性高温气氛是造成焚烧厂高额维护费用的主要原因。使用热喷涂技术对部件表面进行涂层防护可明显提高传统钢材的表面耐腐蚀性能。电弧喷涂由于其易于操作性和低成本,已成为最为成熟的技术之一。要得到可观的腐蚀防护能力,涂层必须有很高的致密度。因此,电弧喷涂必须做出适当调整以适应垃圾焚烧厂的特殊需求。虽然镍基合金和钴基合金代表了当今腐蚀防护的技术水平,但是这些合金非常昂贵。属于同一系列的铁基合金将成为一种经济效益更为可观的防腐蚀材料。最近的研究表明,与铁铬基合金和镍铬基合金相比,铁基合金中加入硅后其耐腐蚀性能得到显著提高。鉴于这一原因,本文开展了对不同成分的铁-铬-硅系合金的研究,重点讨论了该合金的最新研究结果。 | J.Wilden S.Jahn S.Reich V.E.Drescher R.Durham M.Schütze 刘建明 | 2010 | 热喷涂技术2010，2，1： | 7 |
| 5 | A review on photo-thermal catalytic conversion of carbon dioxide显示文摘The conversion of carbon dioxide into value-added products is of great industrial and environmental interest. However, as carbon dioxide is relatively stable, the input energy required for this conversion is a significant limiting factor in the system's performance. By utilising energy from the sun, through a range of key routes, this limitation can be overcome. In this review, we present a comprehensive and critical overview of the potential routes to harvest the sun's energy, primarily through solar-thermal technologies and plasmonic resonance effects. Focusing on the localised heating approach, this review shortlists and compares viable catalysts for the photo-thermal catalytic conversion of carbon dioxide.Further, the pathways and potential products of different carbon dioxide conversion routes are outlined with the reverse water gas shift,methanation, and methanol synthesis being of key interest. Finally, the challenges in implementing such systems and the outlook to the future are detailed. | Ee Teng Kho Tze Hao Tan Emma Lovell Roong Jien Wong Jason Scott Rose Amal | 2017 | Green Energy & Environment2017，2，3： | 7 |
| 6 | 慢性阻塞性肺疾病急性加重患者频繁再入院与其危险因素显示文摘目的 评价慢性阻塞性肺疾病 (COPD)患者急性加重频繁入院的危险因素。方法 调查两家大型医院因COPD急性加重入院的 196名中重度COPD患者。在患者出院时和出院后一个月稳定状态 ,收集患者的临床性状、社会性状、日常护理因素和过去一年中急性加重入院的频率 ,测定肺功能指标及精神状态。结果 196例COPD患者中 ,72 %过去一年中有一次以上再入院 ,4 8%有 2次以上 ,8%有超过 10次再入院。单变量分析显示男性、病程长、嗜用镇痛剂和安眠药、第 1秒用力呼气容量占预计值的百分比 (FEV1% ) <4 5 %、缺乏肺康复训练和严重气促与频繁再入院有显著相关性 (P <0 .0 5 )。多变量分析显示病程长 (OR =2 .6 0 )、FEV1% <4 5 % (OR =2 .0 3)、严重气促 (OR =2 .5 0 )和男性 (OR =3.13)与COPD急性加重再入院有独立显著相关性 (P <0 .0 5 )。结论 COPD急性加重频繁再入院与COPD严重程度。 | 曹振英 Tan Wan Cheng Ng Tze Pin | 2005 | 中国临床保健杂志2005，8，1： | 5 |
| 7 | Enhancement of norfloxacin solubility via inclusion complexation with β-cyclodextrin and its derivative hydroxypropyl-β-cyclodextrin显示文摘The objectives of the study were to investigate the effects of β-cyclodextrin(βCD) and hydroxypropyl-β-cyclodextrin(HPβCD) on the solubility and dissolution rate of norfloxacin prepared using three different methods, at drug to cyclodextrin weight ratios of 1:1, 1:2, 1:4 and 1:8. All the methods increased the solubility and dissolution rate of norfloxacin via inclusion complexation with βCD and HPβCD. Norfloxacin was converted from crystalline to amorphous form through inclusion complexation. Solvent evaporation method was the most effective method in terms of norfloxacin solubilisation, while inclusion complex of HPβCD has higher solubility than βCD complex when prepared using the same procedure. | Gabriel Onn Kit Loh Yvonne Tze Fung Tan Kok-Khiang Peh | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，4： | 4 |
| 8 | Postoperative adjunctive bevacizumab versus placebo in primary trabeculectomy surgery for glaucoma显示文摘AIM: To compare the effectiveness of postoperative adjunctive use of subconjunctival bevacizumab in altering the outcome of primary trabeculectomy in terms of sustained lowering of intraocular pressure(IOP) and reduction of postoperative bleb vascularization and fibrosis.METHODS: A prospective, one center, randomized, placebo-control study. Fifty-nine patients(59 eyes) with uncontrolled IOP under maximal tolerated medical treatment(MTMT) were recruited. A primary trabeculectomy with mitomycin C(MMC) was done and the patients were randomized to either postoperative subconjunctival injection of bevacizumab(1.25 mg/0.05 mL) or balanced salt solution(BSS). Forty-seven patients(47 eyes) completed at least one year of follow up and were included in the study. The main outcome measure was the IOP, and secondary outcome measures include bleb morphology, vascularization, and fibrosis, as well as the need for glaucoma medications and 5-fluorouracil(5-FU) needling.RESULTS: At 1-year follow up, there was no significant difference between groups for IOP(P=0.65), bleb morphology(P=0.65), and the need for glaucoma medications(P=0.65) or 5-FU needling requirements(P=0.11). However, the bevacizumab group had a higher rate of success results, lower use of glaucoma medications after surgery, and optimal bleb aspect in more patients, but more 5-FU needling procedures required. CONCLUSION: A bigger sample size is needed in order to determine whether the differences found in the bevacizumab group are statistically significant. | Sana’Muhsen Javiera Compan Tze Lai Christoph Kranemann Catherine Birt | 2019 | International Journal of Ophthalmology(English edition)2019，12，10： | 4 |
| 9 | Set-theoretic detection of data corruption attacks on cyber physical power systems显示文摘This paper addresses a set-theoretic method for the detection of data corruption cyber-attacks on the load frequency control loop of a networked power system. The system consists of several interconnected control areas forming a power grid. Based on the overall discrete-time network dynamics, a convex and compact polyhedral robust invariant set is extracted and is used as a set-induced anomaly detector. If the state vector exits the invariant set,then an alarm will be activated, and the potential threat is considered disclosed. The attack scenario used to assess the efficiency of the proposed anomaly detector concerns corrupted frequency sensor measurements transmitted to the automatic generation control unit of a compromised control area. Simulation studies highlight the ability of a set-theoretic approach to disclose persistent and intermittent attack patterns even when they occur at the same time with changes in the power load demand. | Efstathios KONTOURAS Anthony TZES Leonidas DRITSAS | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，5： | 4 |
| 10 | 基于ASCP-CS算法的桥式吊车滑模控制器设计显示文摘针对桥式吊车滑模控制器参数设置繁琐以及布谷鸟搜索算法(Cuckoo Search,CS)全局搜索能力不足问题,提出了自适应选取交叉操作算子的布谷鸟搜索算法(Cuckoo Search Algorithm with Adaptively Selecting Crossover Points,ASCP-CS),并将该算法用于桥式吊车滑模控制器参数整定.该算法在CS算法的基础上改进自适应搜索步长,并在交叉操作过程中引入自适应选取染色体交叉点.通过对4种典型寻优函数进行测试的结果表明:ASCP-CS算法具有较好的寻优精度和搜索能力.对桥式吊车滑模控制器采用不同优化算法进行参数整定,仿真实验表明,基于该算法的控制器能更快地实现吊车负载定位,更有效抑制负载摆角,并具有较好的鲁棒性. | 王天雷 谭南林 张人丰 邱炯智 Kenneth Teo Tze Kin | 2020 | 湖南大学学报(自然科学版)2020，47，6： | 3 |
| 11 | Long-Range Balanced Electron- and Hole-Transport Lengths in Organic-Inorganic CH3NH3PbI3显示文摘 | Guichuan Xing Nripan Mathews Shuangyong Sun Swee Sien Lim Yeng Ming Lam Michael Gr?tzel Subodh Mhaisalkar Tze Chien Sum | 2013 | 2013 (6156)2013，，6156： | 3 |
| 12 | Origins of the long-range exciton diffusion in perovskite nanocrystal films: photon recycling vs exciton hopping显示文摘The outstanding optoelectronic performance of lead halide perovskites lies in their exceptional carrier diffusion properties.As the perovskite material dimensionality is reduced to exploit the quantum confinement effects,the disruption to the perovskite lattice,often with insulating organic ligands,raises new questions on the charge diffusion properties.Herein,we report direct imaging of>1μm exciton diffusion lengths in CH3NH3PbBr3 perovskite nanocrystal(PNC)films.Surprisingly,the resulting exciton mobilities in these PNC films can reach 10±2cm^(2)V^(-1) s^(-1),,which is counterintuitively several times higher than the carrier mobility in 3D perovskite films.We show that this ultralong exciton diffusion originates from both efficient inter-NC exciton hopping(via Forster energy transfer)and the photon recycling process with a smaller yet significant contribution.Importantly,our study not only sheds new light on the highly debated origins of the excellent exciton diffusion in PNC films but also highlights the potential of PNCs for optoelearonic applications. | David Giovanni Marcello Righetto Qiannan Zhang Jia Wei Melvin Lim Sankaran Ramesh Tze Chien Sum | 2021 | Light(Science & Applications)2021，10，1： | 3 |
| 13 | Treatment of Complicated Hepatolithiasis with Intrahepatic Biliary Stricture by Ductal Dilatation and Stenting: Long-term Results显示文摘 | Yu Fan Cheng Tze Yu Lee Shyr Ming Sheen-Chen Tung Liang Huang Tai Yi Chen | 2000 | World Journal of Surgery2000，，6： | 2 |
| 14 | Observations and modeling of flat subduction and its geological effects显示文摘Flat subduction refers to low-angle(<10°) or sub-horizontal subduction of oceanic slabs. Flat subduction is only recognized in ~10% of present-day subduction zones, but its impact on the behavior of the overriding plate is particularly strong.For example, flat subduction zones are typically associated with stronger earthquakes. The deformation caused by typical flat subduction will transfer from the trench to the overriding continental interior and form a broad magma belt. The formation mechanism of flat subduction has been linked to the relative buoyancy of subducted oceanic plateaus, overthrusting of the overriding plate, hydrodynamic suction, and trench retreat. However, these mechanisms remain debated. This paper systematically analyzes and summarizes previous studies on flat subduction, and outlines the possible geological effects of flat subduction, such as intracontinental orogeny and magmatism. Using examples from numerical modeling, we discuss the possible formation mechanisms. The most important factors that control the formation of flat subduction are associated with overthrusting of the overriding plate and the arrival of an oceanic plateau at the subduction zone. In addition, trench retreat is necessary to enable flat subduction. Hydrodynamic suction contributes to the reduction of the slab dip angle, but is insufficient to form flat subduction. Future numerical modeling of flat subduction should carry out three-dimensional high-resolution thermo-mechanical simulation, considering the influence of crustal eclogitization(negative buoyancy) and mantle serpentinization(positive buoyancy) of oceanic lithosphere, in combination with geological and geophysical data. | Zhiyong YAN Lin CHEN Xiong XIONG Kai WANG Renxian XIE Hou Tze HSU | 2020 | Science China Earth Sciences2020，63，8： | 2 |
| 15 | 精密微孔加工技术的应用显示文摘有些应用场合,专业领域需要在相对较厚的金属材料上加工出许许多多的精密小孔。想一想筛子和过滤器。如果想用传统的孔加工工艺来生产制造筛子般网格的零件时,它就显得无能为力。但有一种很好的替代解决方案——考虑一下激光加工,但这里用的是电子束钻孔。它几乎可以在所有导电的金属材料上精确、顺利且高效地加工出数量众多的微小孔系。 | Marlina Schütze | 2022 | 现代制造2022，，1： | 2 |
| 16 | Acaricidal activity of Cymbopogon citratus and Azadirachta indica against house dust mites显示文摘Objective:To examine the acaricidal effects of the essential oil of Cymbopogon citratits leaf extract(lemongrass)and ethanolic Azadirachta indica leaf extract(neem)against house dust mites Dermatophagoides farinae(D.farinae)and Dermalophagoides pteronyssinus(D.pteronyssinus).Methods:Twenty-five adults mites were placed onto treated filter paper that is soaked with plant extract and been tested at different concentrations(50.00%,25.00%,12.50%,6.25%and 3.13%)and exposure times(24hrs,48hrs,72hrs and 96 hrs).All treatments were replicated 7 times,and the experiment repeated once.The topical and contact activities of the two herbs were investigated.Results:Mortalities from lemongrass extract were higher than neem for both topical and contact activities.At 50%concentration,both 24 hrs topical and contact exposures to lemongrass resulted in more than 91%mortalities for both species of inites.At the same concentration and exposure time,neem resulted in topical mortalities of 40.3%and 15.7%against D.pteronyssinus and D.farinae respectively;contact mortalities were 8.0%and 8.9%against the 2 mites,respectively.There was no difference in topical mortalities of D.pteronyssinus from exposure to concentrations oflemongrass and neem up to 12.50%;lemongrass was more effective than neem at the higher concentrations.Conclusions:Generally,topical mortalities of D.farinae due to lemongrass are higher than that due to neem.Contact mortalities of lemongrass are always higher that neem against both species of mites. | Azima Laili Hanifah Siti Hazar Awang Ho Tze Ming Suhaili Zainal Abidin Maizatul Hashima Omar | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，5： | 2 |
| 17 | SPQD14120800011178显示文摘 | Kordes Claus Sawitza Iris G?tze Silke Herebian Diran H?ussinger Dieter | 2014 | Journal of Clinical Investigation2014，，12： | 2 |
| 18 | A sequential failure detection technique and its application 显示文摘 | Chen Tze Thong Adams M | 1976 | IEEE Transactions on Automatic Control1976，21，5： | 1 |
| 19 | Lattice point problems and values of quadratic forms显示文摘 | Friedrich G?tze | 2004 | Inventiones mathematicae2004，，1： | 1 |
| 20 | Mechanical aspects of the rare-earth effect显示文摘 | A. Rahmel M. Schütze | 1992 | Oxidation of Metals (-)1992，，3： | 1 |
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