维普中文期刊产品整合服务
213篇 您的检索式:作者名="Unwin N"
    题名 作者 年代 出处 被引量
1糖耐量低减和空腹血糖受损:定义及干预的现状显示文摘由国际糖尿病联盟 (IDF)召集的本次研讨会是为了考察有关糖耐量低减 (IGT)和空腹血糖受损 (IFG)相关的糖尿病和心血管疾病 (CVD)风险的最新文献 ,力图回答三个问题 :(1 )目前的IGT和IFG的定义是否合适 ;(2 )IFG和IGT是危险因子 (riskfactor)、危险标志 (riskmarker)还是疾病 (disease) ;(3)对 :IFG和IGT人群应该采取怎样的干预措施 (如果有的话 ) ?①引起空腹血糖 (FPG)和口服葡萄糖耐量试验(OGTT) 2h血糖 (2hPG)升高的因素并不相同 ,肝脏葡萄糖输出增加和早期胰岛素释放缺陷是前者的特点 ,而外周胰岛素抵抗是后者的显著特征。因此 ,IFG和IGT之间的一致性是有限的。迄今所有的患病率调查发现 ,只有不到一半的IFG人群有IGT ,更少的IGT人群 (2 0 %~ 30 % )有IFG。②大多数的人群研究表明 ,IGT的患病率远高于IFG ,二者的临床表现和性别分布也有差异。IFG在男性更为常见 ,IGT在女性稍微增多。IFG的患病率倾向在中年达到高峰 ,而IGT的患病率逐渐增加直到老龄。③IFG和IGT都与发生糖尿病的风险显著增加有关 ,而最大的风险在于同时具有IFG和IGT的人群。由于在多数人群IGT比IFG更常见 ,所以对于筛查糖尿病高危人群 ,IGT的敏感性较高 (特异性稍差 )。在多数人群 ,60 %的糖尿病人大约 5年前已有IGT或IFG ,另外Unwin N Shaw J Zimmet P Alberti KGMM 金文胜 潘长玉 2003中华内分泌代谢杂志2003,19,1:92
2The N363S polymorphism of the glucocorticoid receptor:potential contribution to central obesity in men and lack of association with other risk factors for coronary heart disease and diabetes mellitus显示文摘Dobson MG Redfern CP Unwin N Clin Endocri0,,:2
3Multiphoton imaging reveals differences in mitochondrial function between nephron segments显示文摘Hall AM Unwin RJ Parker N 2009J Am Soc Nephrol2009,20,6:1
4Activation of the nicotinic acetylcholine receptor involves a switch in conformarion of the subunits显示文摘UNWIN N MIYAZAWA A LI J 2002J Mol Biol2002,319,:1
5Low levels of cardio vascular risk factors and coronary heart disease in a UK Chinese population显示文摘Harland JO Unwin N Bhopal RS 1997J Epidemiol Community Health1997,51,:1
6Standardisation of an European end-user nutrient database for nutritional epidemiology:what can we learn from the EPIC Nutrient Database(ENDB) Project显示文摘Slimani N Deharveng G Unwin I 2007Trends Food Sci Tech2007,18,8:1
7Mortality attributable to diabetes: estimates for the year 2010显示文摘R0glic G Unwin N 2010Diabetes Res Clin Pract2010,87,1:1
8The burden of mortality attributable to diabetes:realistic estimates for the year 2000显示文摘Roglic G Unwin N Bennett PH 0,,09:1
9Health of UK servicemen who served in Persian Gulf War 显示文摘Unwin C Blatehley N Coker W 1999Lancet1999,353,9148:1
10Impaired glucose tolerance and impaired fasting glycaemia: the current status on definition and intervention显示文摘Unwin N Shaw J Zimmet P 2002DiabetMed2002,19,70:1
11Impaired glucose tolerance and impaired fasting glycaemia: the current status on definition and intervention 显示文摘Unwin N Shaw J Zimmet P 2002Diabet Med2002,19,:1
12Impaired glucose tolerance and impaired fasting glycaemia:the current status on definition and intervention显示文摘Unwin N Shaw J Zimmet P 2002Diabet Med2002,19,9:1
13Structure of the Acetylcholine-gated Channel 显示文摘UNWIN N 2002The Roy Soc2002,355,:1
14Heavy metal poisoning:the effects of cadmium on the kidney显示文摘Johri N Jacquillet G Unwin R 2010Biometals2010,23,5:1
15The prevalence of Parkinson's disease in an area of North Tyneside in the North-East of England 显示文摘Porter B Macfarlane R Unwin N 2006Neuroepidemiology2006,26,3:1
16Impaired glucose tolerance and impaired fasting glycaemia:the current status on definition and intervention显示文摘Unwin N Shaw J Zimmet P 2002Diabet Med2002,19,6:1
17Impaired glucose tolerance and impaired fasting glycaemia: the current status on definition and intervention显示文摘Unwin N Shaw J Zimmet P 2002Diabet Med2002,19,9:1
18Structure and Gating Mechanism of the Acetylcholine Receptor Pore 显示文摘MIYAZAWA A FUJIYOSHI Y UNWIN N 2003Nature2003,423,:1
19Impaired glucose tolerance and impaired fasting glycaemia:the current status on definition and intervention 显示文摘Unwin N Shaw J Zimmet P 2002Diabet Med2002,19,9:1
20Diabetes and tubereulosis: the impact of the diabetes epidemic on tubereulosis ineidenee 显示文摘Stevenson CR Forouhi NG Roglie G Williams BG Lauer JA Dye C Unwin N 2007BMC Public Health2007,7,:1
返回顶部 每页显示:
共11页 首页 上一页 第1页 下一页 末页 /11 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费