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| 1 | Pancreatic cancer early detection:Expanding higher-risk group with clinical and metabolomics parameters显示文摘Pancreatic ductal adenocarcinoma(PDAC)is the fourth and fifth leading cause of cancer death for each gender in developed countries.With lack of effective treatment and screening scheme available for the general population,the mortality rate is expected to increase over the next several decades in contrast to the other major malignancies such as lung,breast,prostate and colorectal cancers.Endoscopic ultrasound,with itshighest level of detection capacity of smaller pancreatic lesions,is the commonly employed and preferred clinical imaging-based PDAC detection method.Various molecular biomarkers have been investigated for characterization of the disease,but none are shown to be useful or validated for clinical utilization for early detection.As seen from studies of a small subset of familial or genetically high-risk PDAC groups,the higher yield and utility of imaging-based screening methods are demonstrated for these groups.Multiple recent studies on the unique cancer metabolism including PDAC,demonstrate the potential for utility of the metabolites as the discriminant markers for this disease.In order to generate an early PDAC detection screening strategy available for a wider population,we propose to expand the population of higher risk PDAC group with combination clinical and metabolomics parameters. | Shiro Urayama | 2015 | World Journal of Gastroenterology2015，21，6： | 4 |
| 2 | Characterisation of a microwave induced plasma torch for glass surface modification显示文摘Microwave induced plasma torches find wide applications in material and chemical analysis.Investigation of a coaxial electrode microwave induced plasma(CE–MIP)torch is conducted in this study,making it available for glass surface modification and polishing.A dedicated nozzle is designed to inject secondary gases into the main plasma jet.This study details the adaptation of a characterisation process for CE–MIP technology.Microwave spectrum analysis is used to create a polar plot of the microwave energy being emitted from the coaxial electrode,where the microwave energy couples with the gas to generate the plasma jet.Optical emission spectroscopy analysis is also employed to create spatial maps of the photonic intensity distribution within the plasma jet when different additional gases are injected into it.The CE–MIP torch is experimentally tested for surface energy modification on glass where it creates a super-hydrophilic surface. | Adam BENNETT Nan YU Fengzhou FANG Marco CASTELLI Guoda CHEN Alessio BALLERI Takuya URAYAMA | 2021 | Frontiers of Mechanical Engineering2021，16，1： | 2 |
| 3 | Comprehensive mass spectrometry based metabolic profiling of blood plasma reveals potent discriminatory classifiers of pancreatic cancer 显示文摘 | Urayama S Zou W Brooks K Tolstikov V | 2010 | Rapid Commun Mass Spectrom2010，24，： | 1 |
| 4 | Mycoviruses re- lated to chrysovirus affect vegetative growth in the rice blast fungus Magnaporthe oryzae 显示文摘 | Urayama S Kato S Suzuki Y | 2010 | Journal of General Virology2010，91，： | 1 |
| 5 | Characteriza- tion of Magnaporthe oryzae Chrysovirus 1 structural proteins and their expression in Saccharomyces cerevi- siae 显示文摘 | Urayama S Ohta T Onozuka N | 2012 | Journal of Virology2012，86，15： | 1 |
| 6 | Transgenic myocardial overexpression of prokineticin receptor-2(GPR73b)induces hypertrophy and capillary vessel leakage显示文摘 | URAYAMA K DEDEOGLU D B GUILINI C | 2009 | Cardiovasc Res2009，81，1： | 1 |
| 7 | A dsRNA my- covirus, Magnaporthe oryzae chrysovirusl-B, suppres- ses vegetative growth and development of the rice blast fungus 显示文摘 | Urayama S Sakoda H Takai R | 2014 | Virology2014，448，： | 1 |
| 8 | Heat sensitivity of human parvovirus B19 显示文摘 | Yunoki M Tsujikawa M Urayama T | 2003 | Vox Sang2003，84，3： | 1 |
| 9 | Divergent roles of prokineticin receptors in the endothelial cells:angiogenesis and fenestration显示文摘 | GUILINI C URAYAMA K TURKERI G | 2010 | Am J Physiol Heart Circ Physiol2010，298，3： | 1 |
| 10 | Proper- ties and biodegradability of polymer blends of poly ( L- laetides) with different optical purity of the lactate u- nits 显示文摘 | URAYAMA H KANAMORI T KIMURA Y | 2002 | Macromoleeular Materials &Engineering2002，287，2： | 1 |
| 11 | Inactivation of parvovirus B19 by liquid heating incorporated in the manufacturing process of human intravenous immunoglobiu preparations 显示文摘 | Yunoki M Urayama T Tsujikawa M | 2005 | Br J Haematol2005，128，3： | 1 |
| 12 | Properties and biodegradability of polymer blends of poly(L lactide)s with different optical purity of the lactate units显示文摘 | Urayama H Kanamori T Kimura Y | 2002 | Macromol Mater Eng2002，287，2： | 1 |
| 13 | Flotation separation of SiC from wastes in the silicon wafer slicing process显示文摘 | Shibata J Urayama N Nagae K | | 0，，01： | 1 |
| 14 | Transgenic myocardial overexpression of prokineticin receptor-2(GPR73b)induces hypertrophy and capillary vessel leakage显示文摘 | Urayama K Dedeoglu DB Guilini C | 2009 | Cardiovasc Res2009，81，1： | 1 |
| 15 | Mechanical and thermal properli~~s ~f poly(L-lactide) inc~rporating various inorganic fillers with particle and whisker shapes显示文摘 | Urayama H Ma C Kimura Y | 2003 | Macromol Maler Eng2003，288，7： | 1 |
| 16 | The prokineticin receptor-1(GPR73)promotes cardiomyocyte survival and angiogenesis显示文摘 | Urayama K Guilini C Messaddeq N | 2007 | FASEB J2007，21，11： | 1 |
| 17 | Differential impact of fosa- prepitant on infusion site adverse events between cisplatin - and anthra- cycline- based chemotherapy regimens 显示文摘 | Fujii T Nishimura N Urayama KY | 2015 | Anticancer Res2015，35，1： | 1 |
| 18 | Probing substates in sperm whale myoglobin using high-pressure crystallography显示文摘 | Urayama P Phillips G N Gruner S M | 2002 | Structure2002，10，1： | 1 |
| 19 | Divergent roles of prokineticin receptors in the endothelial cells:angiogenesis and fenestration显示文摘 | Guilini C Urayama K Turkeri G | 2010 | Am J Physiol Heart Circ Physiol2010，298，3： | 1 |
| 20 | Controlled crystal nucleation in the melt- crystallization of poly(blactide) and poly(/-lactide)/poly (d-lactide) stereocomplex显示文摘 | URAYAMA Hiroshi KANAMORI Takeshi FUKUSH- IMA Kazuki | 2003 | Polymer2003，44，19： | 1 |
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