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    题名 作者 年代 出处 被引量
1三白草的化学成分研究(Ⅰ)显示文摘目的 研究三白草 Saururus chinensis(L our.) Baill.的化学成分。方法 采用硅藻土柱层析和反复硅胶柱层析分离纯化 ,通过理化常数测定和光谱分析鉴定其化学结构。结果 从三白草中分得了 3个化合物 ,即三白脂素(saucernetin, )、三白脂素 - 8(saucernetin- 8, )和三白脂素 - 7(saucernetin- 7, )。马敏 阮金兰 Koppaka V.Rao 2001中草药2001,32,1:20
2How would preclinical Alzheimer’s disease (AD pathology) occur? An insight from a genomic instability mouse model显示文摘More than 95%of Alzheimer’s disease(AD)is late-onset,in which patients show clinical cognition/behavior symptoms after age 65.Unlike early-onset AD that comes with mutations in genes directly involved in amyloid metabolism(APP,PSEN),genetic predispositions associated with late-onset AD are harder to pinpoint,and their mechanistic links to AD development need further investigation.Although the development mechanism of late-onset AD remains controversial,amyloid-beta accumulation,initiated in middle age,is widely accepted as the triggering event for early AD pathology(Du Bois et al.,2010;Sterling et al.,2011).Chinthalapally V.Rao Hiroshi Y.Yamada 2021Neural Regeneration Research2021,16,10:1
3Improved Survival After Liver Transplantation in Patients with Hepatopulmonary Syndrome显示文摘S.Gupta H.Castel R. V.Rao M.Picard L.Lilly M. E.Faughnan G.Pomier‐Layrargues 2010American Journal of Transplantation2010,,2:1
4Clinical trial: oral feeding with a soft diet compared with clear liquid diet as initial meal in mild acute pancreatitis显示文摘E.SATHIARAJ S.MURTHY M. J.MANSARD G. V.RAO S.MAHUKAR D. N.REDDY 2008Alimentary Pharmacology & Therapeutics2008,,6:1
5The Current State of Transradial Access:A Perspective on Transradial Outcomes,Learning Curves,and Same-Day Discharge显示文摘The adoption of transradial access in the United States and internationally has been growing over the past few years.In the population of patients presenting with acute coronary syndromes,particularly ST-elevation myocardial infarction,transradial access has the benefit of fewer vascular and bleeding complications and lower mortality rates over transfemoral access.We will examine the current evidence supporting transradial access for several patient populations,including those patients presenting with acute coronary syndromes.We will review the literature regarding the learning curve for transradial access with new operators,as well as experienced transfemoral operators new to transradial access.Finally,we will investigate the role of transradial access in same-day discharge for stable patients undergoing percutaneous coronary intervention.Jennifer A.Rymer Sunil V.Rao 2018Cardiovascular Innovations and Applications2018,,B07:0
6Phytochemical investigation, antioxidant and wound healing activities of Citrullus colocynthis (bitter apple)显示文摘Objective: To undertake metabolite profiling of various plant parts of Citrullus colocynthis, and assess antioxidant and wound healing activities of fractions for therapeutical applications. Methods: Extracts from leaves, stem, root, fruit pulp and seeds were analyzed using gas chromatography-mass spectrometry and high performance liquid chromatography. Variation in antioxidant potential was assayed by 1,1-diphenyl-2-picrylhydrazyl(DPPH) free radical scavenging assay. The extract with highest antioxidant potential was subjected on in-vivo wound healing activity using excision wound model. Results: Metabolite profiling of Citrullus colocynthis identified 70 chemically diverse metabolites from different plant parts by using a combination of GC-MS and HPLC. Concentration of colocynthin, a principal active secondary metabolite, ranged from 3.15 mg/g dry weight to 242.00 mg/g dry weight, the lowest being in leaves and highest in fruit pulp. DPPH radical scavenging activity of free radical(IC50) ranged from 196.44 μg/mL in fruit pulp to 413.33 μg/mL in leaves tissues. Significant wound contraction and increase in hydroxyproline content of granulation tissue were observed with ointment formulated from methanolic extract of fruit pulp. Conclusions: The study indicates that the methanol extract of Citrullus colocynthis fruit pulp when applied topically may promote wound contraction in rat model attributable to the accumulation of colocynthin. The high quantity of colocynthin(242.00 mg/g dry weight) and substantial concentration of 2,4-di-tert butyl phenol(3.2%), squalene(4.2%) and δ-tocopherol(2.5%) make this plant to provide new opportunities for development of medicinal, nutraceutical and dietary supplements with optimized functionality.Sateesh Chandra Gupta Tusha Tripathi Shravan Kumar Paswan Annie G.Agarwal Chandana V.Rao Om P.Sidhu 2018Asian Pacific Journal of Tropical Biomedicine2018,8,8:0
7Deposition of In2-xFexO3 Films by Ultrafast Microwave Heating Technique显示文摘Syed B. Qadri Charbel Fahed Nadeemullah A. Mahadik Heungsoo Kim Michael Osofsky Mulpuri V.Rao 2011材料科学与工程(中英文A版)2011,1,6:0
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