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| 1 | Menopause and cognitive impairment:A narrative review of current knowledge显示文摘A severe impairment of cognitive function characterizes dementia.Mild cognitive impairment represents a transition between normal cognition and dementia.The frequency of cognitive changes is higher in women than in men.Based on this fact,hormonal factors likely contribute to cognitive decline.In this sense,cognitive complaints are more common near menopause,a phase marked by a decrease in hormone levels,especially estrogen.Additionally,a tendency toward worsened cognitive performance has been reported in women during menopause.Vasomotor symptoms(hot flashes,sweating,and dizziness),vaginal dryness,irritability and forgetfulness are common and associated with a progressive decrease in ovarian function and a subsequent reduction in the serum estrogen concentration.Hormone therapy(HT),based on estrogen with or without progestogen,is the treatment of choice to relieve menopausal symptoms.The studies conducted to date have reported conflicting results regarding the effects of HT on cognition.This article reviews the main aspects of menopause and cognition,including the neuroprotective role of estrogen and the relationship between menopausal symptoms and cognitive function.We present and discuss the findings of the central observational and interventional studies on HT and cognition. | Délio Marques Conde Roberto Carmignani Verdade Ana L R Valadares Lucas F B Mella Adriana OrcesiPedro Lucia Costa-Paiva | 2021 | World Journal of Psychiatry2021，11，8： | 3 |
| 2 | Preparation of nat- ural rubber-montmorillonite nanocomposite in aqueous medi- um: Evidence for polymer-platelet adhesion 显示文摘 | Valadares L F l eite C A P Galembeck F | 2006 | Polymer2006，47，2： | 1 |
| 3 | Preparation of natural rubber-montmorillonite nanocomposite in aqueous medium: evidence for polymer-platelet adhesion 显示文摘 | VALADARES L F LEITE C A P GALEMBECK F | 2006 | Polymer2006，47，： | 1 |
| 4 | Effect of replacing alfalfa silage with highmoisture com on ruminal protein synthesis estimatedfrom excretion of total purine derivatives 显示文摘 | VALADARES R F D BRODERICK G A FILHO SC V | 1999 | Journalof Dairy Science1999，82，12： | 1 |
| 5 | Intake and performance of confined bovine fed fresh or ensilaged sug-ar cane based diets and corn silage显示文摘 | Menezes G C D Valadares S D Magalhaes F A | | 0，，05： | 1 |
| 6 | Effect of replacing alfalfa si- lage with high moisture corn on mminal protein syn- thesis estimated from excretion of total purine deriva- tives显示文摘 | VALADARES R F D BRODERICK G A VALADA- RES FILHO S C | 1999 | Journal of Dairy Science1999，82，12： | 1 |
| 7 | Escherichia coli strains from edema disease: O serogroups, and genes for Shiga toxin, enterotoxins, and F18 fimbriae显示文摘 | da Silva A S Valadares G F Penatti M P | 2001 | Vet Microbiol2001，80，3： | 1 |
| 8 | Effect of replacing alfalfa silage with high moisture corn on ruminal protein synthesis estimated from excretion of total purine derivatives 显示文摘 | VALADARES R F D BRODERICK G A VALA- DARES S C | 1999 | Journal of Dairy Science1999，82，： | 1 |
| 9 | Determination of creatinine excretion and evaluation of spot urine sampling in Holstein cattle 显示文摘 | CHIZZOTTI M L FILHO S C V VALADARES R F D | 2008 | Livestock Science2008，113，： | 1 |
| 10 | 2D QSAR studies on thyroid hormone receptor ligands显示文摘 | VALADARES N F CASTILHO M S POLIKARPOVA I | 2007 | Bioorganic & Medicinal Chemistry2007，15，： | 1 |
| 11 | Chemoprotective effect of the tetrahydrofuran lignan grandisin in the in-vivo rodent micronucleus assay 显示文摘 | Valadares M C de Oliveira L M J R de Carvalho F S | 2011 | J Pharm Pharmacol2011，63，3： | 1 |
| 12 | Effect of Agarieus sylvaticus supplementation on nutritional status and adverse e- vents of chemotherapy of breast cancer: a randomized, placebo - controlled, double -blind clinical trial 显示文摘 | VALADARES F GARBI N M CANETE R | 2013 | Indian J Pharmacol2013，45，3： | 1 |
| 13 | Effect of replaeingalfalfa silage with high moisture corn on ruminalprotein synthesis estimated from excretion of total purine derivatives显示文摘 | Valadares R F D Broderick G A ValadresFilho S C | 1999 | J Dairy Sei1999，82，12： | 1 |
| 14 | Intake, apparent digestibility, milk composition and production of lactating cows fed four non protein nitrogen compounds levels显示文摘 | OLIVEIRA A S VALADARES R F D VALADARES F S C | 2001 | Braz J Anim Sci2001，30，13： | 1 |
| 15 | Effect of replacing alfalfa silage with high moisture corn on ruminal protein synthesis estimated from excretion of total purine derivatives显示文摘 | VALADARES R F D BRODERICK G A VALADARES FILHO S C | 1999 | Journal of Dairy Science1999，82，12： | 1 |
| 16 | Validation of NRC (2001) equations for estimation of energy value of feeds in Brazilian conditions显示文摘 | Costa M A L Valadares Filho S C Valadares R F D et el | 2005 | Braz J Anim Sci2005，34，： | 1 |
| 17 | Effect of replacing alfalfa si- lage with high moisture corn on ruminal protein syn- thesis estimated from excretion of total purine deriva- tives显示文摘 | VALADARES R F D BRODERICK G A VALADA- RES FILHO S C | 1999 | Joumal of Dairy Science1999，82，12： | 1 |
| 18 | Effect of replacing alfalfa silage with high moisture corn on ruminal protein synthesis estimated from excretion of total purine derivatives显示文摘 | Valadares R F D Broderick G Valadares F S C | 1999 | Journal of Dairy Science1999，82，： | 1 |
| 19 | The effects of dietary supplementation with Agaricales mushrooms and other medicinal fungi on breast cancer:Evidence-based medicine显示文摘 | Novaes MR Valadares F Reis MC | 2011 | Clinics(Sao Paulo)2011，66，12： | 1 |
| 20 | Effect of replacing alfalfa silage with high moisture corn on nutri- ent utilization and milk production显示文摘 | VALADARES S C BRODERICK G A VALADARES R F D | 2000 | J Dairy Sei2000，83，： | 1 |
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