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| 1 | Diagnosis,treatment and prevention of type 2 diabetes mellitus in children and adolescents显示文摘During the last two decades,there have been several reports of an increasing incidence of type 2 diabetes mellitus(T2 DM) in children and adolescents,especially among those belonging to minority ethnic groups.This trend,which parallels the increases in prevalence and degree of pediatric obesity,has caused great concern,even though T2 DM remains a relatively rare disease in children.Youth T2 DM differs not only from type 1 diabetes in children,from which it is sometimes difficult to differentiate,but also from T2 DM in adults,since it appears to be an aggressive disease with rapidly progressive β-cell decline,high treatment failure rate,and accelerated development of complications.Despite the recent research,many aspects of youth T2 DM still remain unknown,regarding both its pathophysiology and risk factor contribution,and its optimal management and prevention.Current management approaches include lifestyle changes,such as improved diet and increased physical activity,together with pharmacological interventions,including metformin,insulin,and the recently approved glucagonlike peptide-1 analog liraglutide.What is more important for everyone to realize though,from patients,families and physicians to schools,health services and policy-makers alike,is that T2 DM is a largely preventable disease that will be addressed effectively only if its major contributor(i.e.,pediatric obesity) is confronted and prevented at every possible stage of life,from conception until adulthood.Therefore,relevant comprehensive,coordinated,and innovative strategies are urgently needed. | Anastasios Serbis Vasileios Giapros Eleni P Kotanidou Assimina Galli-Tsinopoulou Ekaterini Siomou | 2021 | World Journal of Diabetes2021，12，4： | 4 |
| 2 | Greenland temperature response to climate forcing during the last deglaciation显示文摘 | Christo B Vasileios G Jeffrey P S | 2014 | Science2014，345，： | 1 |
| 3 | Bidding strategies for electricity producers in a competitive electricity marketplace显示文摘 | Vasileios P G Anastasios G B | 2004 | IEEE Trans on Power Systems2004，19，1： | 1 |
| 4 | Effects of dietary probiotics on performance, egg quality and yolk/sermn cholesterol of laying hens显示文摘 | Sattar B Rasoul P Vasileios B | 2006 | J Anim Vet Adv2006，1，： | 1 |
| 5 | Psychrotrophic members of Leuconostoc gasicomitatum,Leuconostoc gelidum and Lactococcus piscium dominate at the end of shelf-life in packaged and chilled-stored food products in Belgium显示文摘 | VASILEIOS P CINDY S PAUL De Vos | 2014 | Food Microbiology2014，39，： | 1 |
| 6 | Metal-heptaiodide interactions in cyclomaltoheptaose (β- cyclodextrin) polyiodide complexes as detected via Raman spectroscopy显示文摘 | Vasileios G C John C P Glikeria K | 2008 | Carbohydrate Research2008，343，： | 1 |
| 7 | Artificial neural networks in spectrum fatigue life prediction of composite materials显示文摘 | Vassilopoulos Anastasios P Georgopoulos Efstratios F Dionysopoulos Vasileios | 2007 | International Journal of Fatigue2007，29，1： | 1 |
| 8 | Bidding strategies for electricity producers in a competitive marketplace 显示文摘 | Vasileios P G Anastasios G B | 2004 | IEEE Transactions on Power Systems2004，19，1： | 1 |
| 9 | Serum transferrin receptor,ferritin,and reticulocyte maturity indices during the fwst year of life in‘large'preterm infants显示文摘 | VASSILIKI S VASILEIOS G KONSTANTINA P | 2007 | Ear J Haem2007，79，： | 1 |
| 10 | A single-time survey method to predict the daily weed density for weed con- trol decision-making显示文摘 | Roherta M Vasileios P Vasileia D | 2011 | Weed Science2011，59，2： | 1 |
| 11 | COVID-19 and liver injury in individuals with obesity显示文摘Coronavirus disease 2019 is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 that manifests as a variety of clinical manifestations,including liver damage commonly detected by a hepatocellular pattern from liver function tests.Liver injury is associated with a worse prognosis overall.Conditions associated with the severity of the disease include obesity and cardiometabolic comorbidities,which are also associated with nonalcoholic fatty liver disease(NAFLD).The presence of NAFLD,similarly to obesity,is associated with an unfavourable impact on the coronavirus disease 2019 outcome.Individuals with these conditions could present with liver damage and elevated liver function tests due to direct viral cytotoxicity,systemic inflammation,ischemic or hypoxic liver damage or drug side effects.However,liver damage in the setting of NAFLD could also be attributed to a pre-existing chronic low-grade inflammation associated with surplus and dysfunctional adipose tissue in these individuals.Here we investigate the hypothesis that a pre-existing inflammatory status is exacerbated after severe acute respiratory syndrome coronavirus 2 infection,which embodies a second hit to the underestimated liver damage. | Ioannis G Lempesis Eleni Karlafti Petros Papalexis George Fotakopoulos Kyriakos Tarantinos Vasileios Lekakis Stavros P Papadakos Evangelos Cholongitas Vasiliki E Georgakopoulou | 2023 | World Journal of Gastroenterology2023，29，6： | 0 |
| 12 | Primary adrenal Ewing sarcoma:A systematic review of the literature显示文摘BACKGROUND Ewing sarcoma(ES)is a malignant neoplasm of neuroectodermal origin and is commonly observed in children and young adults.The musculoskeletal system is the main body system impacted and ES is rarely seen in the visceral organs particularly the adrenal gland.AIM To present a comprehensive review of primary adrenal ES,with emphasis on diagnosis,therapy and oncological outcomes.METHODS A systematic review of the literature was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020.PubMed/MEDLINE,EMBASE and Google Scholar bibliographic databases were searched to identify articles from 1989 to 2022 and included patients with ES/primitive neuroectodermal tumor(PNET)of the adrenal gland.PubMed,Google Scholar and EMBASE medical databases were searched,combining the terms“adrenal”,“ES”and“PNET”.Demographic,clinical,pathological and oncological data of patients were analyzed by SPSS version 29.0.RESULTS A total of 52 studies were included for review(47 case reports and 5 case series)with 66 patients reported to have primary adrenal ES.Mean age at diagnosis was 26.4±15.4 years(37.9%males,57.6%females,sex not reported in 3 cases).The most frequent complaint was abdominal/flank pain or discomfort(46.4%)followed by a palpable mass(25.0%),and the average duration of symptoms was 2.6±3.1 mo.The imaging modality of choice was computed tomography scan(81.5%),followed by magnetic resonance imaging(20.4%).Preoperative staging revealed that 17 tumors(27.9%)were metastatic and 14 patients had inferior vena cava or renal vein neoplastic thrombus at initial diagnosis.Open adrenalectomy was performed in the majority of cases(80.0%),of which 27.9%required more extensive resection.Minimally invasive surgery was attempted in 8.2%of tumors.Complete surgical resection was achieved in 89.4%of the patients.Adjuvant therapy was administered to 32 patients,in the form of chemotherapy(62.5%),radiotherapy(3.1%)or combination(34.4%).Median overall survival was 15 mo and 24-mo overall survival was 40.5%.Median disease-free survival was 10 mo and 24-mo disease-free survival was 33.3%.CONCLUSION The significant progress in molecular biology and genetics of ES does not reflect on patient outcomes.ES remains an aggressive tumor with a poor prognosis and high mortality. | Dimitrios K Manatakis Ioannis Tsouknidas Emmanouil Mylonakis Nikolaos Tasis Maria Ioanna Antonopoulou Vasileios Acheimastos Aikaterini Mastoropoulou Dimitrios P Korkolis | 2023 | World Journal of Clinical Cases2023，11，28： | 0 |
| 13 | Closing the gap: astrocytes and brain metastasis显示文摘 | Gino B Ferraro David P Kodack Vasileios Askoxylakis Rakesh K Jain | 2016 | Cell Research2016，26，9： | 0 |
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