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| 1 | Transforming growth factor-β and fibrosis显示文摘Transforming growth factor-β (TGF-β), a prototype of multifunctional cytokine, is a key regulator of extracellular matrix (ECM) assembly and remodeling. Specifically, TGF-β isoforms have the ability to induce the expression of ECM proteins in mesenchymal cells, and to stimulate the production of protease inhibitors that prevent enzymatic breakdown of the ECM. Elevated TGF-β expression in affected organs, and subsequent deregulation of TGF-β functions, correlates with the abnormal connective tissue deposition observed during the onset of fibrotic diseases. During the last few years, tremendous progress has been made in the understanding of the molecular aspects of intracellular signaling downstream of the TGF-β receptors. In particular, Smad proteins, TGF-β receptor kinase substrates that translocate into the cell nucleus to act as transcription factors, have been studied extensively. The role of Smad3 in the transcriptional regulation of typeⅠcollagen gene expression and in the development of fibrosis, demonstrated both in vitro and in animal models with a targeted deletion of Smad3, is of critical importance because it may lead to novel therapeutic strategies against these diseases. This review focuses on the mechanisms underlying Smad modulation of fi brillar collagen expression and how it relates to fi brotic processes. | Franck Verrecchia Alain Mauviel | 2007 | World Journal of Gastroenterology2007，13，22： | 113 |
| 2 | Discussion of an economic framework for conservative accounting and Bushman and Piotroski (2006)显示文摘 | Wayne Guay Robert Verrecchia | 2006 | Journal of Accounting and Economics2006，，1： | 2 |
| 3 | 不同声刺激颈前庭诱发肌源性电位诊断上半规管裂的有效性显示文摘目的:颈前庭诱发肌源性电位(cVEMP)测试在评估球囊和末梢前庭神经功能方面有重要的临床意义,也可评估上半规管裂综合征(SCD)患者对声音的前庭超敏性。cVEMP测试使用的常规刺激是高强度500Hz的短纯音。本研究的目的是比较高强度短纯音和低强度的click,诊断SCD的有效性。方法:研究38例单侧SCD患者对500Hz的短纯音和click响应的cVEMP振幅。结果:采用高强度500 Hz短纯音的cVEMP测试不能区分SCD患者。高强度500Hz的刺激可能饱和。使用90和80dB nHL clicks少有饱和度。用80和90dB nHL clicks测试与只用90dB nHL clicks相比,并没有明显的优势。结论:90dB nHL clicks和高强度500 Hz的短纯音cVEMP,都可用于筛查SCD。 | 张甦琳 孔维佳 KRISTER BRANTBERG LUCA VERRECCHIA | 2016 | 临床耳鼻咽喉头颈外科杂志2016，30，4： | 2 |
| 4 | Pre-announcement and event-period private information显示文摘 | Oliver Kim Robert E. Verrecchia | 1998 | Journal of Accounting and Economics1998，，3： | 2 |
| 5 | Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes显示文摘 | L. Vija D. Farge J.-F. Gautier P. Vexiau C. Dumitrache A. Bourgarit F. Verrecchia J. Larghero | 2009 | Diabetes and Metabolism2009，，2： | 2 |
| 6 | Essays on disclosure显示文摘 | VERRECCHIA R | 2001 | Journal of Accounting and Economics2001，32，13： | 1 |
| 7 | Disclosure,Liquidity and the Cost of Capital显示文摘 | Diamond D Verrecchia R E | | 0，，66： | 1 |
| 8 | Market Liquidity and Volume around Earnings Announcements 显示文摘 | Kim O Verrecchia R E | 1995 | Journal of Accounting and Economics1995，，1： | 1 |
| 9 | Evidence that Volume Sustains Stock Price Changes显示文摘 | STICKEL S E VERRECCHIA R E | 1994 | Financial Analyst Journal1994，50，6： | 1 |
| 10 | Expression of MAGE gene family in primary and metastatic human breast cancer: implications for tumor antigen specific immunotherapy显示文摘 | Russo V Traversari C Verrecchia A | | 0，，： | 1 |
| 11 | Excimer laserassisted lamellar keratoplasty for the surgical treatment of keratoconus 显示文摘 | Spadea L Giammaxia D Fiasca A Verrecchia V | 2009 | J Cataract Refract Surg2009，35，1： | 1 |
| 12 | The economic consequences of increased disclosure 显示文摘 | Leuz C Verrecchia R | 2000 | Journal of Accounting Research2000，38，： | 1 |
| 13 | Transforming growth factor-beta and fibrosis显示文摘 | Verrecchia F Mauviel A | | 0，，22： | 1 |
| 14 | The economic consequences of increased disclosure显示文摘 | Leuz C Verrecchia R E | 2000 | Journal of Accounting Research2000，，38： | 1 |
| 15 | Protective effect of melatonin in a model of traumatic brain injury in mice显示文摘 | Margaill I Verrecchia C | 1998 | J Pineal Res1998，25，1： | 1 |
| 16 | Transforming growth factor-beta and fibrosis 显示文摘 | Verrecchia F Mauviel A | 2007 | World J Gastroenterol2007，13，29： | 1 |
| 17 | Transforming growth factor2betasignaling through the Smad pathway:role in extracellularmatrix gene expression and regulation显示文摘 | Verrecchia F Mauviel A | 2002 | Invest Derma2tol2002，118，2： | 1 |
| 18 | Disclosure, Liquidity and the Cost of Capital显示文摘 | Diamond D C Verrecchia R E | 1991 | Journal of Finance1991，46，： | 1 |
| 19 | Trading volume and pricereactions to public announcements 显示文摘 | Kim 0 Verrecchia R | 1991 | Journal ofAccounting Research1991，29，30： | 1 |
| 20 | Testing vestib- ular-evoked myo-genic potentials with 90-dB clicks is effective in the diagnosis of superior canal dehiscence syndrome显示文摘 | BRANTBERG K VERRECCHIA L | 2009 | Audiol Neurootol2009，14，： | 1 |
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